Search

Howard Federoff Phones & Addresses

  • 36 Dowling Cir, Parkville, MD 21234 (410) 823-6173 (410) 823-7763
  • 36 Dowling Cir APT T1, Parkville, MD 21234 (410) 823-6173
  • Baltimore, MD

Publications

Isbn (Books And Publications)

Parkinson's Disease: The Life Cycle of the Dopamine Neuron

View page
Author

Howard Federoff

ISBN #

0801879973

Us Patents

Plasma Microrna Markers Of Upper Limb Recovery Following Human Stroke

View page
US Patent:
20200239959, Jul 30, 2020
Filed:
Jan 24, 2020
Appl. No.:
16/751700
Inventors:
- Washington DC, US
Xiaogang Zhong - College Park MD, US
Massimo S. Fiandaca - Millersville MD, US
Howard J. Federoff - Irvine CA, US
Amrita K. Cheema - Potomac MD, US
Alexander W. Dromerick - Washington DC, US
Assignee:
Georgetown University - Washington DC
International Classification:
C12Q 1/6883
Abstract:
Methods of determining if a subject has an increased risk of poor recovery after suffering a stroke and methods of treating a subject recovering from a stroke. The methods comprise analyzing at least one plasma sample taken from the subject to assess a microRNA (miRNA) profile of the subject and comparing the subject's miRNA profile with a normal miRNA profile, to determine if the subject's miRNA profile is altered compared to a normal miRNA profile. An alteration of the subject's miRNA profile is indicative that the subject has an increased risk of poor recovery after suffering a stroke.

Lrrk-2-Mediated Neuronal Toxicity

View page
US Patent:
20150018301, Jan 15, 2015
Filed:
Nov 8, 2010
Appl. No.:
13/508180
Inventors:
Byoung Dae Lee - Cockeysville MD, US
Ted M. Dawson - Baltimore MD, US
Valina L. Dawson - Baltimore MD, US
Andrew B. West - Birmingham AL, US
Howard Federoff - Bethesda MD, US
Assignee:
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
International Classification:
A61K 31/553
A61K 31/404
A61K 31/7064
A61K 31/122
A61K 31/416
US Classification:
514 49, 435184, 514410, 514680, 514406, 514414, 514418
Abstract:
Leucine-rich repeat kinase-2 (LRRK2) mutations are a common cause of Parkinson's disease. Inhibitors of LRRK2 kinase that are protective in in vitro and in vivo models of LRRK2-induced neurodegeneration were identified. The presently disclosed subject matter establishes that LRRK2-induced degeneration of neurons in vivo is kinase dependent and that LRRK2 kinase inhibition provides a potential new neuroprotective paradigm for treating Parkinson's disease.

Amazon

Parkinson's Disease: The Life Cycle Of The Dopamine Neuron (Annals Of The New York Academy Of Sciences)

Parkinson's Disease: The Life Cycle of the Dopamine Neuron (Annals of the New York Academy of Sciences)

View page

Parkinson's Disease (PD), a progressive neurological disorder arising from degeneration of dopaminergic neurons in the substantia nigra region of the brain, is characterized by impairment of movement control. It progresses from symptoms such as tremor and muscular rigidity to total disability and de...

Binding

Paperback

Pages

370

Publisher

New York Academy of Sciences

ISBN #

0801879973

EAN Code

9780801879975

ISBN #

3

Imaging And The Aging Brain, Volume 1097 (Annals Of The New York Academy Of Sciences)

Imaging and the Aging Brain, Volume 1097 (Annals of the New York Academy of Sciences)

View page

Advances in imaging are occurring at a brisk pace, and imaging techniques have great potential to act as pre-symptomatic predictors of disease as well as to chart the course of a disease. Neuroimaging has greatly advanced the understanding of brain function and its relationship to the anatomical sub...

Binding

Paperback

Pages

252

Publisher

Wiley-Blackwell

ISBN #

1573316598

EAN Code

9781573316590

ISBN #

2

Parkinson's Disease: The Life Cycle Of The Dopamine Neuron (Annals Of The New York Academy Of Sciences)

Parkinson's Disease: The Life Cycle of the Dopamine Neuron (Annals of the New York Academy of Sciences)

View page

Book by

Binding

Hardcover

Pages

360

Publisher

New York Academy of Sciences

ISBN #

157331448X

EAN Code

9781573314480

ISBN #

1

Parkinson's disease; the life cycle of the dopamine neuron. (Annals of the New Y

View page
Author

Ed. by Howard J. Federoff et al.

Binding

Paperback

Publisher

N.Y. Academy of Sciences.

ISBN #

5

Howard Federoff from Baltimore, MD Get Report