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Hongji J Ren

from San Diego, CA
Age ~61

Hongji Ren Phones & Addresses

  • 9150 Meadowrun Ct, San Diego, CA 92129
  • 9505 Genesee Ave, San Diego, CA 92121 (858) 458-9022
  • 524 Maude Ave, Sunnyvale, CA 94085 (408) 732-7361
  • 9150 Meadowrun Ct, San Diego, CA 92129 (858) 484-9590

Work

Company: Molecular dynamics (israel) ltd 1999 to 2002 Position: Senior scientist

Education

Degree: Doctorates, Doctor of Philosophy School / High School: University of Alberta 1989 to 1994 Specialities: Philosophy

Skills

Capillary Electrophoresis • Dna Sequencing • Sequencing • Analytical Chemistry • Electrophoresis • Genotyping • Assay Development • Microfabrication • Fluorescence • Genomics • Bioinformatics • Biotechnology • Flow Cell Fabrication • Image Analysis • Bead Array • Dna • Life Sciences • Solid Particle Kitting/Distribution • Protein Chemistry • R

Languages

Mandarin • English • Japanese

Industries

Biotechnology

Resumes

Resumes

Hongji Ren Photo 1

Staff Scientist At Illumina Inc

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Location:
San Diego, CA
Industry:
Biotechnology
Work:
Molecular Dynamics (Israel) Ltd 1999 - 2002
Senior Scientist

Illumina 1999 - 2002
Staff Scientist at Illumina Inc

University of Ottawa 1997 - 1999
Postdoctoral Fellow

University of Alberta 1995 - 1997
Postdoctoral Fellow
Education:
University of Alberta 1989 - 1994
Doctorates, Doctor of Philosophy, Philosophy
Nankai University 1980 - 1987
Master of Science, Masters, Chemistry
Skills:
Capillary Electrophoresis
Dna Sequencing
Sequencing
Analytical Chemistry
Electrophoresis
Genotyping
Assay Development
Microfabrication
Fluorescence
Genomics
Bioinformatics
Biotechnology
Flow Cell Fabrication
Image Analysis
Bead Array
Dna
Life Sciences
Solid Particle Kitting/Distribution
Protein Chemistry
R
Languages:
Mandarin
English
Japanese

Publications

Us Patents

Systems And Methods For Automated Quality Control Of Polymer Synthesis

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US Patent:
20070003941, Jan 4, 2007
Filed:
Jul 1, 2005
Appl. No.:
11/173952
Inventors:
Nels Olson - San Diego CA, US
Bahram Kermani - San Diego CA, US
Hongji Ren - San Diego CA, US
Theo Kotseroglou - San Diego CA, US
Assignee:
Illumina, Inc. - San Diego CA
International Classification:
C12Q 1/68
G06F 19/00
US Classification:
435006000, 702019000, 702020000
Abstract:
The invention provides systems and methods for evaluating synthetic reactions such as polymer synthesis reactions. Evaluation of a synthetic reaction product can be based on a quantitative measure of synthesis such as coupling efficiency or yield, and various parameters determined from a separation record obtained for the synthetic reaction product. The invention further provides methods for evaluating a separation method based on various parameters determined from a separation record. The invention can be used to select an appropriate treatment for a synthetic reaction product such as a separation treatment or treatments related to further processing for the desired product. The methods are particularly useful for automated selection of treatments for synthetic reaction products.

Dynamic Autofocus Method And System For Assay Imager

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US Patent:
20100157086, Jun 24, 2010
Filed:
Dec 15, 2009
Appl. No.:
12/638770
Inventors:
DARREN R. SEGALE - SAN DIEGO CA, US
JOHN A. MOON - SAN DIEGO CA, US
HONGJI REN - SAN DIEGO CA, US
Assignee:
ILLUMINA, INC - SAN DIEGO CA
International Classification:
H04N 5/225
G06K 9/40
US Classification:
3482221, 382255, 348E05024
Abstract:
A method and system are provided for controlling focus dynamically of a sample imager. The method comprises scanning a sample with an optical assembly that apportions the sample into regions based on a scan pattern. The optical assembly has a focal setting with respect to the sample. The method further comprises shifting the focal setting of the optical assembly during scanning of the sample, and detecting one or more images representative of one of the regions from the sample. The one or more images have associated degrees of focus corresponding to the focal setting of the optical assembly. The method analyzes the image(s) to obtain a focus score or scores corresponding thereto, where the focus scores represent a degree to which the optical assembly was in focus when detecting the images. The method adjusts the focus setting based on the focus score(s).

Compositions And Methods For Providing Substances To And From An Array

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US Patent:
20110105356, May 5, 2011
Filed:
May 5, 2009
Appl. No.:
12/991121
Inventors:
Chad F. DeRosier - San Diego CA, US
John A. Moon - San Diego CA, US
Fiona E. Black - San Diego CA, US
Robert Yang - San Diego CA, US
Hongji Ren - San Diego CA, US
David L. Heiner - San Diego CA, US
International Classification:
C40B 30/04
C40B 50/00
C40B 50/06
C40B 40/00
US Classification:
506 9, 506 27, 506 26, 506 13
Abstract:
Methods, kits, systems, and multilayer transfer media for transferring a substance to and from an array are disclosed herein. Also disclosed herein are methods of detecting a substance that has been transferred to an array.

Dynamic Autofocus Method And System For Assay Imager

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US Patent:
20130235388, Sep 12, 2013
Filed:
Mar 29, 2013
Appl. No.:
13/853492
Inventors:
John A. Moon - San Diego CA, US
Hongji Ren - San Diego CA, US
Assignee:
ILLUMINA, INC. - SAN DIEGO CA
International Classification:
G01B 11/24
US Classification:
356609
Abstract:
Method of detecting surface features of a microarray. The method includes providing a microarray to an optical scanner, wherein the microarray includes a surface having features. The method also includes carrying out a scanning process using the optical scanner, wherein the scanning process includes: (i) acquiring images of sequential regions on the surface, wherein a defocus spread is applied to the optical scanner during the acquiring, (ii) determining a focus score for the images, (iii) adjusting the optical scanner to a different defocus spread based on the focus score, and (iv) repeating (i) through (iii) at the different defocus spread, thereby acquiring images of further sequential regions on the surface. The method also includes analyzing the images to distinguish different target molecules at the features of the microarray. The images that are analyzed were acquired at the defocus spread and at the different defocus spread during the scanning process.

Polymer Coatings

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US Patent:
20140079923, Mar 20, 2014
Filed:
Mar 4, 2013
Appl. No.:
13/784368
Inventors:
Wayne N. George - Essex, GB
Andrew A. Brown - Essex, GB
Daniel Bratton - Essex, GB
Hongji Ren - San Diego CA, US
Ryan C. Smith - San Diego CA, US
International Classification:
C09D 135/00
US Classification:
428209, 524555, 4281951, 428210
Abstract:
The present disclosure relates to polymer coatings covalently attached to the surface of a substrate and the preparation of the polymer coatings, such as poly(N-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (PAZAM), in the formation and manipulation of substrates, such as molecular arrays and flow cells. The present disclosure also relates to methods of preparing a substrate surface by using beads coated with a covalently attached polymer, such as PAZAM, and the method of determining a nucleotide sequence of a polynucleotide attached to a substrate surface described herein.

Predicting Structured Illumination Parameters

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US Patent:
20210364773, Nov 25, 2021
Filed:
Aug 6, 2021
Appl. No.:
17/396478
Inventors:
- San Diego CA, US
Stanley S. Hong - Palo Alto CA, US
Robert Langlois - San Diego CA, US
Hongji Ren - San Diego CA, US
Kevin Wayne Bartig - San Diego CA, US
Rico Otto - San Diego CA, US
Olga Andreevna Souverneva - San Diego CA, US
International Classification:
G02B 21/36
G02B 21/06
G06T 7/11
G02B 21/26
Abstract:
Implementations of the disclosure are directed to predicting structured illumination parameters for a particular point in time, space, and/or temperature using estimates of structured illumination parameters obtained from structured illumination images captured by a structured illumination system. Particular implementations are directed to predicting structured illumination frequency, phase, orientation, and/or modulation order parameters.

Dynamic Autofocus Method And System For Assay Imager

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US Patent:
20210271074, Sep 2, 2021
Filed:
May 3, 2021
Appl. No.:
17/302418
Inventors:
- San Diego CA, US
John Moon - Rancho Santa Fe CA, US
Hongji Ren - San Diego CA, US
International Classification:
G02B 26/12
G01N 21/64
G02B 21/24
H04N 5/232
G02B 26/10
G01B 11/24
C12Q 1/6874
Abstract:
A method for scanning a microarray, including (a) providing a microarray to an optical scanner, wherein the microarray includes a surface having features having different target molecules; (b) scanning the surface in the x or y direction to acquire optical signals from the features at sequential regions of the surface, wherein the focus setting between the optical scanner and the surface is dynamically controlled in real time by repeatedly (i) adding a predetermined focal offset, thereby introducing an error in the focus setting, and (ii) adjusting the focus setting to reduce the error in the focus setting, thereby acquiring the optical signals from different regions at different degrees of focus such that a subset of the regions that are scanned have an introduced focus error; and (c) analyzing the optical signals that are obtained at the different degrees of focus to identify the different target molecules.

Polymer Coatings

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US Patent:
20210254151, Aug 19, 2021
Filed:
Mar 1, 2021
Appl. No.:
17/188109
Inventors:
- San Diego CA, US
Andrew A. Brown - Cambridge, GB
Daniel Bratton - Cambridge, GB
Hongji Ren - San Diego CA, US
Ryan Christopher Smith - San Diego CA, US
International Classification:
C12Q 1/6874
B05D 3/06
C09D 133/26
C09D 135/00
C12Q 1/6806
Abstract:
The present disclosure relates to polymer coatings covalently attached to the surface of a substrate and the preparation of the polymer coatings, such as poly(N-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (PAZAM), in the formation and manipulation of substrates, such as molecular arrays and flow cells. The present disclosure also relates to methods of preparing a substrate surface by using beads coated with a covalently attached polymer, such as PAZAM, and the method of determining a nucleotide sequence of a polynucleotide attached to a substrate surface described herein.
Hongji J Ren from San Diego, CA, age ~61 Get Report