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Hermann Theodora Oppermann

from Dover, MA
Age ~77
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Also known as:
Hermann A Oppermann, Herman Oppermann, Herman Opperman, Oppermann Hermann, Opermann Hermann
Phone and address:
14 Wakeland Rd, Dover, MA 02030
(508) 785-1170
Connected to:
Aaron E Opperman, 62Astrid M Oppermann, 30Benjamin A Opperman, 45Bill V Opperman, 65Cassandra N Opperman, 46Christine M Opperman, 38Debbie A Opperman, 69Dennis E Opperman, 71Derek E Opperman, 38Diane Opperman, 72

Hermann Oppermann Phones & Addresses

  • 14 Wakeland Rd, Dover, MA 02030 (508) 785-1170 (508) 785-2325
  • 25 Summer Hill Rd, Medway, MA 02053 (508) 533-1349
  • San Francisco, CA
  • Hopkinton, MA
  • 14 Wakeland Rd, Dover, MA 02030

Work

Position: Executive, Administrative, and Managerial Occupations

Education

Degree: High school graduate or higher

Emails

d***[email protected]

Business Records

Name / Title
Company / Classification
Phones & Addresses
Hermann Oppermann
Vice-President
Brookline T A B
Newspapers-Publishing/Printing
254 2 Ave, Needham, MA 02494

Publications

Us Patents

Soluble Morphogenic Protein Complex Compositions Of Matter

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US Patent:
6395883, May 28, 2002
Filed:
Mar 13, 1995
Appl. No.:
08/402542
Inventors:
William K. Jones - Brookline MA
Ronald F. Tucker - Holliston MA
David C. Rueger - Hopkinton MA
Hermann Oppermann - Medway MA
Engin Ozkaynak - Milford MA
Assignee:
Curis, Inc. - Cambridge MA
International Classification:
C07K 14475
US Classification:
530399, 530397, 530350, 514 2
Abstract:
Disclosed are novel compositions of morphogenic proteins constituting soluble forms of these proteins, antibodies that distinguish between soluble and mature forms, and method for producing these morphogenic proteins and antibodies.

Morphogen Treatments For Limiting Proliferation Of Epithelial Cells

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US Patent:
6399569, Jun 4, 2002
Filed:
Jun 5, 1995
Appl. No.:
08/461113
Inventors:
Charles M. Cohen - Medway MA
Marc F. Charette - Needham MA
David C. Rueger - Hopkinton MA
Hermann Oppermann - Medway MA
Roy H. L. Pang - Etna NH
Engin Ozkaynak - Milford MA
John E. Smart - Weston MA
Assignee:
Curis, Inc. - Cambridge MA
International Classification:
A61K 3818
US Classification:
514 12, 530350
Abstract:
Disclosed are methods and compositions for maintaining the integrity of the gastrointestinal tract luminal lining in a mammal, including (1) limiting epithelial cell proliferation, (2) inhibiting ulcerative lesion formation, (3) inhibiting inflammation normally associated with ulcerative diseases, and (4) stimulating the repair of ulcerative lesions and the regeneration of the luminal tissue. The methods and compositions include a therapeutically effective amount of a morphogen as defined herein.

Morphogen-Enhanced Survival And Repair Of Neural Cells

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US Patent:
6495513, Dec 17, 2002
Filed:
May 31, 1995
Appl. No.:
08/456033
Inventors:
David C. Rueger - Hopkinton MA
Hermann Oppermann - Medway MA
Engin Ozkaynak - Milford MA
Roy H. L. Pang - Etna NH
Charles M. Cohen - Medway MA
Assignee:
Curis, Inc. - Cambridge MA
International Classification:
A61K 3800
US Classification:
514 2, 514 12
Abstract:
Disclosed are therapeutic treatment methods, compositions and devices for maintaining neural pathways in a mammal, including enhancing survival of neurons at risk of dying, inducing cellular repair of damaged neurons and neural pathways, and stimulating neurons to maintain their differentiated phenotype. In one embodiment, the invention provides means for stimulating CAM expression in neurons. The invention also provides means for evaluating the status of nerve tissue, including means for detecting and monitoring neuropathies in a mammal. The methods, devices and compositions include a morphogen or morphogen-stimulating agent provided to the mammal in a therapeutically effective concentration.

Protein-Induced Tissue Morphogenesis

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US Patent:
6565843, May 20, 2003
Filed:
Mar 14, 1995
Appl. No.:
08/404113
Inventors:
Charles M. Cohen - Medway MA
Roy H. L. Pang - Medway MA
Hermann Oppermann - Medway MA
David C. Rueger - West Roxbury MA
Assignee:
Curis, Inc. - Cambridge MA
International Classification:
A61K 3512
US Classification:
424 931, 435325, 435363, 435366, 435370, 435372, 514 2, 514 12
Abstract:
The invention provides methods, compositions and devices for inducing tissue-specific regeneration in a mammal, or for stimulating proliferation of mammalian progenitor cells. The present methods, compositions and devices make use of osteogenic protein (OP- ), which is appreciated herein as a tissue morphogen, i. e. , a substance competent to induce tissue-specific morphogenesis of mammalian body tissues in addition to bone and/or cartilage. Alternatively, the present methods, compositions and devices make use of other naturally-occurring or biosynthetic proteins sharing a defined structural and functional relationship with OP- and thus appreciated herein also to function as tissue morphogens. Optionally, OP- or a related protein can be used alone or when adsorbed on a support matrix which provides an anchoring substratum for proliferation and/or differentiation of progenitor cells during tissue-specific morphogenesis. In another embodiment, OP- or a related protein is used to stimulate mammalian progenitor cells ex vivo, such that the stimulated cells, when disposed in vivo in a mammal, undergo tissue-specific morphogenesis to produce replacement tissue at a nonskeletal tissue locus in need thereof (i. e.

Methods And Compositions For The Treatment And Prevention Of Parkinsons Disease

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US Patent:
6506729, Jan 14, 2003
Filed:
Sep 25, 1997
Appl. No.:
08/938622
Inventors:
David C. Rueger - Southborough MA
Kuber T. Sampath - Holliston MA
Charles M. Cohen - Weston MA
Hermann Oppermann - Medway MA
Roy H. L. Pang - Etna NH
Assignee:
Curis, Inc. - Cambridge MA
International Classification:
A61K 3818
US Classification:
514 12, 514 2, 530350, 530402
Abstract:
Disclosed are therapeutic treatment methods, compositions and devices for maintaining neural pathways in a mammal, including enhancing survival of neurons at risk of dying, inducing cellular repair of damaged neurons and neural pathways, and stimulating neurons to maintain their differentiated phenotype. In one embodiment, the invention provides means for stimulating CAM expression in neurons. The invention also provides means for evaluating the status of nerve tissue, including means for detecting and monitoring neuropathies in a mammal. The methods, devices and compositions include a morphogen or morphogen-stimulating agent provided to the mammal in a therapeutically effective concentration.

Protein-Induced Morphogenesis In Liver Tissue

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US Patent:
6531445, Mar 11, 2003
Filed:
Dec 15, 1999
Appl. No.:
09/464206
Inventors:
Charles M. Cohen - Medway MA
Roy H. L. Pang - Medway MA
Hermann Oppermann - Medway MA
David C. Rueger - Hopkinton MA
Assignee:
Curis, Inc. - Cambridge MA
International Classification:
A61K 3816
US Classification:
514 2, 514 12, 424 851
Abstract:
Disclosed are 1) amino acid sequence data, structural features, homologies and various other data characterizing morphogenic proteins, 2) methods of producing these proteins from natural and recombinant sources and from synthetic constructs, 3) morphogenic devices comprising these morphogenic proteins and a suitably modified tissue-specific matrix, and 4) methods of inducing non-chondrogenic tissue growth in a mammal.

Osteogenic Devices

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US Patent:
6551995, Apr 22, 2003
Filed:
Sep 4, 1998
Appl. No.:
09/148925
Inventors:
Hermann Oppermann - Medway MA
Engin Ozkaynak - Milford MA
David C. Rueger - Hopkinton MA
Roy H. L. Pang - Medway MA
Assignee:
Stryker Corporation - Kalamazoo MI
International Classification:
A61K 3816
US Classification:
514 12, 514 2, 424423, 424426, 623 16, 623 11, 435 691
Abstract:
Disclosed are (1) osteogenic devices comprising a matrix containing substantially pure natural-sourced mammalian osteogenic protein; (2) DNA and amino acid sequences for novel polypeptide chains useful as subunits of dimeric osteogenic proteins; (3) vectors carrying sequences encoding these novel polypeptide chains and host cells transfected with these vectors; (4) methods of producing these polypeptide chains using recombinant DNA technology; (5) antibodies specific for these novel polypeptide chains; (6) osteogenic devices comprising these recombinantly produced proteins in association with an appropriate carrier matrix; and (7) methods of using the osteogenic devices to mimic the natural course of endochondral bone formation in mammals.

Method Of Using Recombinant Osteogenic Protein To Repair Bone Or Cartilage Defects

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US Patent:
6586388, Jul 1, 2003
Filed:
Oct 24, 1997
Appl. No.:
08/957425
Inventors:
Hermann Oppermann - Medway MA
Engin Ozkaynak - Milford MA
David C. Rueger - Hopkinton MA
Roy H. L. Pang - Medway MA
Assignee:
Stryker Corporation - Kalamazoo MI
International Classification:
A61K 3816
US Classification:
514 2, 514 12, 530350
Abstract:
Disclosed are (1) osteogenic devices comprising a matrix containing substantially pure natural-sourced mammalian osteogenic protein; (2) DNA and amino acid sequences for novel polypeptide chains useful as subunits of dimeric osteogenic proteins; (3) vectors carrying sequences encoding these novel polypeptide chains and host cells transfected with these vectors; (4) methods of producing these polypeptide chains using recombinant DNA technology; (5) antibodies specific for these novel polypeptide chains; (6) osteogenic devices comprising these recombinantly produced proteins in association with an appropriate carrier matrix; and (7) methods of using the osteogenic devices to mimic the natural course of endochondral bone formation in mammals.
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Hermann Theodora Oppermann from Dover, MA, age ~77 Get Report