US Patent:
20220298166, Sep 22, 2022
Inventors:
- North Chicago IL, US
Henrique D. Teixeira - Green Oaks IL, US
Ahmed A. Othman - Libertyville IL, US
Ben Klünder - Ludwigshafen, DE
International Classification:
C07D 487/14
A61K 47/38
A61K 47/12
A61K 31/4985
A61K 9/00
A61K 9/20
Abstract:
The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3Himidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis and atopic dermatitis), kits, methods of synthesis, and products-by-process.