Resumes
Resumes
Hartmut Schroeder Phones & Addresses
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44 Jackson Cir, Franklin, MA 02038 (508) 528-3612
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13003 Hunters Ridge St, San Antonio, TX 78230
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Elkhart, IN
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44 Jackson Cir, Franklin, MA 02038 (508) 577-4527
Work
Position:
Farmer
Education
Degree:
High school graduate or higher
Emails
Publications
Us Patents
Oligonucleotide Probes Bearing Quenchable Fluorescent Labels, And Methods Of Use Thereof
View pageUS Patent:
6465175, Oct 15, 2002
Filed:
Sep 3, 1998
Appl. No.:
09/146157
Inventors:
Thomas Horn - Berkeley CA
Hartmut R. Schroeder - Franklin MA
Brian D. Warner - Martinez CA
Ellen Fiss - Albany CA
Todd Sells - Bellingham MA
Say-Jong Law - Westwood MA
Hartmut R. Schroeder - Franklin MA
Brian D. Warner - Martinez CA
Ellen Fiss - Albany CA
Todd Sells - Bellingham MA
Say-Jong Law - Westwood MA
Assignee:
Bayer Corporation - Tarrytown NY
International Classification:
C12Q 168
US Classification:
435 6, 536 221, 536 253, 436501
Abstract:
Methods are provided for reducing background signals encountered in nucleic acid hybridization assays and other assays that involve hybridization of a labeled oligomer to its complement. The method is premised on the significant reduction of signal generation that occurs when a quenchable dye-labeled oligomer forms a hybrid complex. In addition, a method is provided for enhancing the detectable signal emitted from an amplification multimer hybridized to an oligomer probe to which a quenchable dye has been conjugated through a linker such that the emission from the dye is not quenched upon hybrid complex formation. Novel oligonucleotide probes are also provided that comprise an oligomer to which has been directly or indirectly through a linker a quenchable dye.
Applications Of Acridinium Compounds And Derivatives In Homogeneous Assays
View pageUS Patent:
7319041, Jan 15, 2008
Filed:
Sep 27, 2002
Appl. No.:
10/260504
Inventors:
Anand Natrajan - Manchester NH, US
Todd Sells - Bellingham MA, US
Hartmut Schroeder - Franklin MA, US
Guohan Yang - Mansfield MA, US
David Sharpe - Foxboro MA, US
Qingping Jiang - Northborough MA, US
Hana Lukinsky - Cambridge MA, US
Say-Jong Law - Westwood MA, US
Todd Sells - Bellingham MA, US
Hartmut Schroeder - Franklin MA, US
Guohan Yang - Mansfield MA, US
David Sharpe - Foxboro MA, US
Qingping Jiang - Northborough MA, US
Hana Lukinsky - Cambridge MA, US
Say-Jong Law - Westwood MA, US
Assignee:
Siemens Medical Solutions Diagnostic - Tarrytown NY
International Classification:
G01N 33/533
G01N 33/536
G01N 33/53
C07D 219/00
G01N 33/536
G01N 33/53
C07D 219/00
US Classification:
436546, 436536, 436800, 435 71, 435 793, 435968, 546102
Abstract:
Chemiluminescent acridinium compounds are used in homogeneous assays to determine the concentration of an analyte in a sample without strong acid or strong base treatment. The chemiluminescent acridinium compounds include acridinium esters with electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus to inhibit pseudo-base formation, or acridinium sulfonamides with or without electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus.
Immunoassay Probe
View pageUS Patent:
7514270, Apr 7, 2009
Filed:
Apr 10, 2003
Appl. No.:
10/411441
Inventors:
Eugene K. Achter - Lexington MA, US
Hartmut Richard Schroeder - Franklin MA, US
Stephen S. Trotta - Woburn MA, US
Hartmut Richard Schroeder - Franklin MA, US
Stephen S. Trotta - Woburn MA, US
Assignee:
Instrumentation Laboratory Company - Lexington MA
International Classification:
G01N 33/553
G01N 21/00
G01N 21/00
US Classification:
436526, 436 47, 436807, 422 65, 422 681, 209214, 210222, 210695
Abstract:
An analytical instrument for the immobilization of antigens to be detected in an immunoassay using mangetizable beads. The instrument includes a probe containing magnetizable particles and a plurality of magnetic devices for applying a magnetic field gradient to the particles in the probe reservoir. The probe is movable between the plurality of magnetic devices and at least one of the probe positions may be used to immobilize the magnetic particles in the fluid medium and at least another position may be used to resuspend the particles in a fluid medium.
Applications Of Acridinium Compounds And Derivatives In Homogeneous Assays
View pageUS Patent:
7875467, Jan 25, 2011
Filed:
Nov 21, 2007
Appl. No.:
11/944131
Inventors:
Anand A. Natrajan - Manchester NH, US
Todd Sells - Bellingham MA, US
Hartmut Schroeder - Franklin MA, US
Guohan Yang - Mansfield MA, US
David Sharpe - Foxborough MA, US
Qingping Jiang - East Walpole MA, US
Hana Lukinsky - Portland OR, US
Say-Jong Law - Westwood MA, US
Todd Sells - Bellingham MA, US
Hartmut Schroeder - Franklin MA, US
Guohan Yang - Mansfield MA, US
David Sharpe - Foxborough MA, US
Qingping Jiang - East Walpole MA, US
Hana Lukinsky - Portland OR, US
Say-Jong Law - Westwood MA, US
Assignee:
Siemens Healthcare Diagnostics Inc. - Tarrytown NY
International Classification:
G01N 33/533
G01N 33/536
G01N 33/53
C07D 219/08
G01N 33/536
G01N 33/53
C07D 219/08
US Classification:
436546, 436536, 436800, 435 71, 435 793, 435968, 546104
Abstract:
Chemiluminescent acridinium compounds are used in homogeneous assays to determine the concentration of an analyte in a sample without strong acid or strong base treatment. The chemiluminescent acridinium compounds include acridinium esters with electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus to inhibit pseudo-base formation, or acridinium sulfonamides with or without electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus.
Resuspension Of Magnetizable Particles
View pageUS Patent:
20060133954, Jun 22, 2006
Filed:
Dec 15, 2005
Appl. No.:
11/300956
Inventors:
Hartmut Schroeder - Franklin MA, US
Eugene Achter - Lexington MA, US
Eugene Achter - Lexington MA, US
Assignee:
Instrumentation Laboratory Company - Lexington MA
International Classification:
B01L 3/00
US Classification:
422061000, 366273000, 422082050, 422099000
Abstract:
A kit for clinical analysis, including a vessel containing magnetizable particles and a magnetic stirring element. A device for distributing magnetizable particles in a fluid including a platform for supporting a vessel containing a fluid, magnetizable particles, and a magnetic stirring element, where the magnetic stirring element moves in a horizontal plane within the vessel. A method for distributing magnetizable particles in a fluid including the steps of providing a vessel containing a magnetic stirring element and a fluid containing magnetizable particles, moving the magnetic stirring element in the vessel, and distributing the magnetizable particles in the fluid.
Novel Applications Of Acridinium Compounds And Derivatives In Homogeneous Assays
View pageUS Patent:
20090029349, Jan 29, 2009
Filed:
Nov 21, 2007
Appl. No.:
11/944112
Inventors:
Anand A. Natrajan - Manchester NH, US
Todd Sells - Bellingham MA, US
Hartmut Schroeder - Franklin MA, US
Guohan Yang - Mansfield MA, US
David Sharpe - Foxborough MA, US
Qingping Jiang - East Walpole MA, US
Hana Lukinsky - Portland OR, US
Say-Jong Law - Westwood MA, US
Todd Sells - Bellingham MA, US
Hartmut Schroeder - Franklin MA, US
Guohan Yang - Mansfield MA, US
David Sharpe - Foxborough MA, US
Qingping Jiang - East Walpole MA, US
Hana Lukinsky - Portland OR, US
Say-Jong Law - Westwood MA, US
Assignee:
Siemens Medical Solutions Diagnostics - Tarrytown NY
International Classification:
C12Q 1/70
G01N 33/53
C12Q 1/68
G01N 33/53
C12Q 1/68
US Classification:
435 5, 435 794, 435 6, 435 72
Abstract:
Chemiluminescent acridinium compounds are used in homogeneous assays to determine the concentration of an analyte in a sample without strong acid or strong base treatment. The chemiluminescent acridinium compounds include acridinium esters with electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus to inhibit pseudo-base formation, or acridinium sulfonamides with or without electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus.
Chemiluminescent Phthalhydrazide-Labeled Protein And Polypeptide Conjugates
View pageUS Patent:
42972736, Oct 27, 1981
Filed:
Jan 14, 1980
Appl. No.:
6/111809
Inventors:
Robert T. Buckler - Edwardsburg MI
Hartmut R. Schroeder - Elkhart IN
Hartmut R. Schroeder - Elkhart IN
Assignee:
Miles Laboratories, Inc. - Elkhart IN
International Classification:
C07G 700
US Classification:
260112B
Abstract:
Chemiluminescent-labeled conjugates of the formula: ##STR1## wherein one of R. sup. 1 and R. sup. 2 is hydrogen and the other is --NR. sup. 3 R. sup. 4 ; R. sup. 3 is hydrogen or straight chain alkyl containing 1-4 carbon atoms and R. sup. 4 is L(CO)--HN--(CH. sub. 2). sub. n wherein n=2-8 and L(CO)-- is an antigenic protein or polypeptide bound through an amide bond. The labeled conjugates are useful as reagents in specific binding assays for determining antigenic proteins or polypeptides, or their binding partners, in liquid media.
Bis-Phthalimides
View pageUS Patent:
42128056, Jul 15, 1980
Filed:
Apr 30, 1979
Appl. No.:
6/034249
Inventors:
Robert T. Buckler - Edwardsburg MI
Hartmut R. Schroeder - Elkhart IN
Hartmut R. Schroeder - Elkhart IN
Assignee:
Miles Laboratories, Inc. - Elkhart IN
International Classification:
C07D20948
C07D23730
C07D23730
US Classification:
260326N
Abstract:
Bis-phthalimides of the formula: ##STR1## wherein one of R. sup. 9 and R. sup. 10 is hydrogen and the other is--NR. sup. 11 R. sup. 12 ; R. sup. 11 is hydrogen or straight chain alkyl containing 1-4 carbon atoms and R. sup. 12 is ##STR2## wherein n=2-8. The compounds are intermediates in the synthesis of chemiluminescent phthalhydrazide-labeled conjugates which are useful as reagents in specific binding assays for determining ligands or their specific binding partners in liquid media.