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Haiou Yang Phones & Addresses

  • 2133 Meadow Lakes Dr, Watkinsville, GA 30677
  • Cary, NC
  • Atlanta, GA
  • 2816 Avent Ferry Rd, Raleigh, NC 27606 (919) 854-1164
  • 3000 Kings Ct, Raleigh, NC 27606 (919) 854-1164

Resumes

Resumes

Haiou Yang Photo 1

Haiou Yang

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Haiou Yang Photo 2

Scientist Ii/Project Lead At Kbi Biopharma

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Position:
Scientist/Project Lead at KBI Biopharma
Location:
Raleigh-Durham, North Carolina Area
Industry:
Biotechnology
Work:
KBI Biopharma - Durham since Sep 2012
Scientist/Project Lead

Grifols, Inc Jun 2011 - Sep 2012
Process Development Scientist

Talecris Biotherapeutics Dec 2008 - Sep 2012
Process Development Scientist

North Carolina State University Aug 2002 - Nov 2008
Research Assistant
Education:
North Carolina State University 2002 - 2008
PhD, Chemical Engineering
Tsinghua University 1999 - 2002
MS, Chemical Engineering
Sichuan University
BS, Chemistry
Skills:
Purification
Chromatography
Protein Purification
Protein Chemistry
SDS-PAGE
ELISA
Cell Culture
UV/Vis
Analytical Chemistry
Western Blotting
Filtration
High Throughput Screening
Process Simulation
Aseptic Processing
Design of Experiments
Mammalian Cell Culture
Centrifugation
Ultrafiltration
Biotechnology
HPLC
Languages:
Chinese

Publications

Us Patents

Purification Of Immunoglobulins Using Affinity Chromatography And Peptide Ligands

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US Patent:
20060153834, Jul 13, 2006
Filed:
Jan 13, 2005
Appl. No.:
11/035016
Inventors:
Ruben Carbonell - Raleigh NC, US
Haiou Yang - Raleigh NC, US
Guangquan Wang - Raleigh NC, US
Patrick Gurgel - Cary NC, US
International Classification:
G01N 33/53
A61K 39/395
C07K 7/06
C40B 40/10
US Classification:
424133100, 435007100, 530329000, 530330000
Abstract:
An immunoglobulin binding peptide having the general formula, from amino terminus to carboxy terminus, of Z-R—R—R—R—R—R—X, is described, wherein: Ris H or Y; Ris a hydrophobic, preferentially aromatic, amino acid (for example W, F, Y, V); Ris a positively charged or aromatic amino acid (for example R, H, F, W); Ris a hydrophobic or positively charged amino acid (for example G, Y, R, K, L); Ris a positively charged or aromatic amino acid (for example W, F, R, H, Y); Ra random amino acid but preferably hydrophobic or negatively charged (for example V, W, L, D, H); X is present or absent and when present is a linking group; and Z is present or absent and when present is a capping group bonded to the N terminus of R; and wherein the amino acids of said peptide are in D form, L form, or a combination thereof. Methods of using such peptides for the purification of Immunoglobulins are also described

Purification Of Immunoglobulins Using Affinity Chromatography And Peptide Ligands

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US Patent:
20090005261, Jan 1, 2009
Filed:
Jul 23, 2008
Appl. No.:
12/178004
Inventors:
Ruben Carbonell - Raleigh NC, US
Haiou Yang - Raleigh NC, US
Guangquan Wang - Raleigh NC, US
Patrick Gurgel - Cary NC, US
Assignee:
North Carolina State University - Raleigh NC
International Classification:
C40B 30/04
C07K 16/00
G01N 33/544
G01N 33/545
G01N 33/53
US Classification:
506 9, 5303871, 436529, 436532, 435 71
Abstract:
An immunoglobulin binding peptide having the general formula, from amino terminus to carboxy terminus, of Z-R—R—R—R—R—R—X, is described, wherein: Ris H or Y; Ris a hydrophobic, preferentially aromatic, amino acid (for example W, F, Y, V); Ris a positively charged or aromatic amino acid (for example R, H, F, W); Ris a hydrophobic or positively charged amino acid (for example G, Y, R, K, L); Ris a positively charged or aromatic amino acid (for example W, F, R, H, Y); Ra random amino acid but preferably hydrophobic or negatively charged (for example V, W, L, D, H); X is present or absent and when present is a linking group; and Z is present or absent and when present is a capping group bonded to the N terminus of R; and wherein the amino acids of said peptide are in D form, L form, or a combination thereof. Methods of using such peptides for the purification of Immunoglobulins are also described

Non-Chromatographic Separation Of Polypeptides Using The Combination Of A Steric Exclusion Agent And A Charge Neutralization Agent

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US Patent:
20190002495, Jan 3, 2019
Filed:
Aug 12, 2016
Appl. No.:
15/752397
Inventors:
- Durham NC, US
Haiou Yang - Watkinsville GA, US
Carnley Norman - Cary NC, US
Eric Suda - Apex NC, US
Assignee:
KBI Biopharma, Inc. - Durham NC
International Classification:
C07K 1/30
C12N 9/00
C07K 16/00
Abstract:
The present invention relates to methods of separating polypeptides of interest from contaminants, including DNA and undesired polypeptides, in a common fluid by precipitation of the polypeptides of interest or, alternatively, the contaminants using the combination of steric exclusion agents and charge neutralization agents.

Purification Of Immunoglobulins Using Affinity Chromatography And Peptide Ligands

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US Patent:
20140243210, Aug 28, 2014
Filed:
May 2, 2012
Appl. No.:
13/462373
Inventors:
Ruben Carbonell - Raleigh NC, US
Haiou Yang - Raleigh NC, US
Patrick Gurgel - Cary NC, US
International Classification:
C07K 1/22
G01N 33/68
US Classification:
506 2, 530329, 525 541, 5303871, 5303905, 5303881, 5303891, 5303873, 506 9
Abstract:
An immunoglobulin binding peptide having the general formula, from amino terminus to carboxy terminus, of Z—R—R—R—R—R—R—X, is described, wherein: Ris H or Y; Ris a hydrophobic, preferentially aromatic, amino acid (for example W, F, Y, V); Ris a positively charged or aromatic amino acid (for example R, H, F, W); Ris a hydrophobic or positively charged amino acid (for example G, Y, R, K, L); Ris a positively charged or aromatic amino acid (for example W, F, R, H, Y); Ra random amino acid but preferably hydrophobic or negatively charged (for example V, W, L, D, H); X is present or absent and when present is a linking group; and Z is present or absent and when present is a capping group bonded to the N terminus of R; and wherein the amino acids of said peptide are in D form, L form, or a combination thereof. Methods of using such peptides for the purification of Immunoglobulins are also described
Haiou Yang from Watkinsville, GA Get Report