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Guy L Cavet

from Hillsborough, CA
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Also known as:
Guy L Chapman
Phone and address:
2820 Adeline Dr, Burlingame, CA 94010
Connected to:
Tess A Cavet, 47Amanda B Cavett, 33Chad D Cavett, 52Ella Cavett, 67Heather M Cavett, 37Janet I Cavett, 62Kendall N Cavett, 30Scott A Cavett, 40Steven R Cavett, 58Terry E Cavett, 49

Guy Cavet Phones & Addresses

  • 2820 Adeline Dr, Burlingame, CA 94010
  • Hillsborough, CA
  • San Mateo, CA
  • San Francisco, CA
  • Kenmore, WA
  • Redwood City, CA
  • Seattle, WA
  • 981 Baileyana Rd, Hillsborough, CA 94010

Resumes

Resumes

Guy Cavet Photo 1

Entrepreneur And Consultant

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Location:
981 Baileyana Rd, Hillsborough, CA 94010
Industry:
Biotechnology
Work:
Nodality Inc. since Mar 2013
CIO, Head of Computational Sciences
Kaggle Jun 2012 - Feb 2013
Vice President Life Sciences
Crescendo Bioscience Mar 2008 - May 2012
Vice President, Informatics
Genentech Feb 2005 - Mar 2008
Senior Scientist, Bioinformatics
Rosetta Inpharmatics Dec 1999 - Feb 2005
Group Leader
Education:
Stanford University 1999 - 1999
University of Cambridge 1994 - 1999
University of Cambridge 1991 - 1994
Skills:
Bioinformatics
Genomics
Molecular Biology
Data Analysis
Lifesciences
Biomarker Discovery
Biochemistry
Biotechnology
Drug Discovery
Biostatistics
Life Sciences
Computational Biology
Data Mining
Sequencing
Biomarkers
Genetics
Microarray
Oncology
Personalized Medicine
Immunology
Sequence Analysis
Clinical Development
Laboratory
Dna Sequencing
Informatics
Algorithm Design
Science
Protein Chemistry
Systems Biology
Research
R
Microarray Analysis
Scientific Computing
Data Visualization
Leadership
Molecular Diagnostics
Cancer
Translational Medicine
Microarrays
Diagnostics
Target Identification
Gene Expression Profiling
Software Engineering
User Interface Design
Scientific Writing
Strategic Planning
Database Design
Research Strategy
Organizational Leadership
Software Design
Languages:
English
Guy Cavet Photo 2

Cio, Head Of Computational Sciences At Nodality Inc.

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Position:
CIO, Head of Computational Sciences at Nodality Inc.
Location:
San Francisco Bay Area
Industry:
Biotechnology
Work:
Nodality Inc. since Mar 2013
CIO, Head of Computational Sciences
Kaggle Jun 2012 - Feb 2013
Vice President Life Sciences
Crescendo Bioscience Mar 2008 - May 2012
Vice President, Informatics
Genentech Feb 2005 - Mar 2008
Senior Scientist, Bioinformatics
Rosetta Inpharmatics Dec 1999 - Feb 2005
Group Leader
Education:
Stanford University 1999 - 1999
University of Cambridge 1994 - 1999
University of Cambridge 1991 - 1994
Skills:
Bioinformatics
Biostatistics
Biomarker Discovery
Genomics
Microarrays
Biochemistry
Life Sciences
Informatics
Personalized Medicine
Drug Discovery
Molecular Biology
Immunology
Oncology
Biotechnology
Biomarkers
Diagnostics
Target Identification
Gene Expression Profiling
Systems Biology
Computational Biology
Genetics
Sequence Analysis
Software Engineering
User Interface Design
Scientific Writing
Strategic Planning
Data Mining
Database Design
Research Strategy
Scientific Computing
Algorithm Design
Organizational Leadership
Data Visualization
Data Analysis
Software Design
Lifesciences
Leadership
Research
Molecular Diagnostics
Microarray

Publications

Us Patents

Method Of Designing Sirnas For Gene Silencing

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US Patent:
7962316, Jun 14, 2011
Filed:
Oct 27, 2004
Appl. No.:
10/577696
Inventors:
Aimee L. Jackson - Seattle WA, US
Steven R. Bartz - Seattle WA, US
Julja Burchard - Mount Vernon WA, US
Peter S. Linsley - Seattle WA, US
Wei Ge - Redmond WA, US
Guy L. Cavet - Burlingame CA, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
G06F 17/10
G06F 7/60
US Classification:
703 2, 702 19, 703 11, 707723, 707748, 536 231
Abstract:
The present invention provides a method for identifying siRNA target motifs in a transcript using a position-specific score matrix approach. The invention also provides a method for identifying off-target genes of an siRNA using a position-specific score matrix approach. The invention further provides a method for designing siRNAs with higher silencing efficacy and specificity. The invention also provides a library of siRNAs comprising siRNAs with high silencing efficacy and specificity.

Method For Selecting Sirnas From A Plurality Of Sirnas For Gene Silencing

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US Patent:
8457902, Jun 4, 2013
Filed:
May 4, 2011
Appl. No.:
13/100836
Inventors:
Aimee L. Jackson - Seattle WA, US
Steven R. Bartz - Seattle WA, US
Julja Burchard - Mount Vernon WA, US
Peter S. Linsley - Seattle WA, US
Ge Wei - Redmond WA, US
Guy L. Cavet - Burlingame CA, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
G06F 7/00
US Classification:
702 19, 702 20, 703 11, 707700
Abstract:
The present invention provides a method for identifying siRNA target motifs in a transcript using a position-specific score matrix approach. The invention also provides a method for identifying off-target genes of an siRNA using a position-specific score matrix approach. The invention further provides a method for designing siRNAs with higher silencing efficacy and specificity. The invention also provides a library of siRNAs comprising siRNAs with high silencing efficacy and specificity.

Method And/Or Apparatus For Determining Codons

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US Patent:
8457903, Jun 4, 2013
Filed:
Sep 9, 2011
Appl. No.:
13/229228
Inventors:
Robin A. Emig - Redwood City CA, US
Richard John Fox - Kirkwood MO, US
Claes Gustafsson - Belmont CA, US
Sridhar Govindarajan - Redwood City CA, US
Jeremy S. Minshull - Los Altos CA, US
Guy Cavet - Seattle WA, US
Assignee:
Codexis Mayflower Holdings, LLC - Redwood City CA
International Classification:
G06F 19/00
C40B 50/00
C40B 50/02
US Classification:
702 19, 702 20, 506 23, 506 24
Abstract:
Computer processing methods and/or systems for minimizing and/or optimizing data strings in accordance with rules and options. Minimized data strings can represent data sequences important in certain biologic analyses and/or syntheses. In specific embodiments, a request is generated by a user at a client system and received by a server system. The server system accesses initial data indicated or provided by the client system. The server system then performs an analysis to minimize the data needed for further reactions. In specific embodiments, a server can use proprietary methods or data at the server side while protecting those proprietary methods and data from access by the client system.

Biomarkers And Methods For Measuring And Monitoring Inflammatory Disease Activity

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US Patent:
20110137851, Jun 9, 2011
Filed:
Oct 15, 2010
Appl. No.:
12/905984
Inventors:
Guy L. Cavet - Burlingame CA, US
Yijing Shen - San Mateo CA, US
Nicholas Knowlton - Choctaw OK, US
Michael Centola - Oklahoma City OK, US
Assignee:
CRESCENDO BIOSCIENCE - South San Francisco CA
OKLAHOMA MEDICAL RESEARCH FOUNDATION - Oklahoma City OK
International Classification:
G06N 5/02
G06F 17/10
US Classification:
706 54, 703 2
Abstract:
Biomarkers useful for diagnosing and assessing inflammatory disease are provided, along with kits for measuring their expression. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. The biomarkers include at least two biomarkers selected from the DAIMRK group and the score is a disease activity index (DAI).

Genetic Variations Associated With Drug Resistance

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US Patent:
20110177099, Jul 21, 2011
Filed:
Mar 12, 2009
Appl. No.:
12/922420
Inventors:
Mark Lackner - South San Francisco CA, US
Lukas C. Amler - Foster City CA, US
Guy Cavet - Burlingame CA, US
Carol O'Brien - Pacifica CA, US
Ajay Pandita - Redwood City CA, US
International Classification:
A61K 39/395
C12Q 1/68
C40B 30/04
G01N 33/574
A61K 31/713
A61P 35/00
US Classification:
4241741, 435 611, 506 9, 435 71, 514 44 A, 4241781
Abstract:
Methods and compositions are provided to determine if a cancer is resistant to treatment with anti-mitotic agents, including treatment with T-DM1. The methods relate to determining if the ABCC3 gene is amplified and/or overexpressed in the cancer.

Method And Apparatus For Codon Determining

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US Patent:
7702464, Apr 20, 2010
Filed:
Aug 30, 2002
Appl. No.:
10/232770
Inventors:
Robin A. Emig - Oakland CA, US
Richard John Fox - Redwood City CA, US
Claes Gustafsson - Belmont CA, US
Sridhar Govindarajan - Redwood City CA, US
Jeremy S. Minshull - Los Altos CA, US
Guy Cavet - Seattle WA, US
Assignee:
Maxygen, Inc. - Redwood City CA
International Classification:
G06F 19/00
C40B 50/00
C40B 50/02
US Classification:
702 19, 702 20, 506 23, 506 24
Abstract:
Computer processing methods and/or systems for minimizing and/or optimizing data strings in accordance with rules and options. Minimized data strings can represent data sequences important in certain biologic analyses and/or syntheses. In specific embodiments, a request is generated by a user at a client system and received by a server system. The server system accesses initial data indicated or provided by the client system. The server system then performs an analysis to minimize the data needed for further reactions. In specific embodiments, a server can use proprietary methods or data at the server side while protecting those proprietary methods and data from access by the client system.

Broadly Neutralizing Antibodies Against Hiv

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US Patent:
20230002480, Jan 5, 2023
Filed:
Feb 22, 2022
Appl. No.:
17/677757
Inventors:
Dongkyoon Kim - Palo Alto CA, US
Guy Cavet - Hillsborough CA, US
- Baltimore MD, US
- Washington DC, US
International Classification:
C07K 16/10
A61P 31/18
A61K 39/42
A61K 45/06
Abstract:
The present invention provides broadly neutralizing antibodies against HIV, compositions comprising the same and methods of use thereof.

Broadly Neutralizing Antibodies Against Hiv

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US Patent:
20200172601, Jun 4, 2020
Filed:
Jun 22, 2018
Appl. No.:
16/626163
Inventors:
Dongkyoon Kim - Palo Alto CA, US
Guy Cavet - Hillsborough CA, US
- Baltimore MD, US
- Washington DC, US
Marzena E. Pazgier - Mt. Airy MD, US
William David Tolbert - Baltimore MD, US
International Classification:
C07K 16/10
A61K 39/42
A61P 31/18
Abstract:
The present invention provides broadly neutralizing antibodies against HIV, compositions comprising the same and methods of use thereof. Specifically, the invention provides isolated anti-HIV antibodies that are capable of neutralizing at least 95% of the HIV pseudoviruses listed in Table 1 and neutralizing 100% of the HIV clade B, G and D viruses listed in Table 1 with an IC50 value of less than 50 ug/mL. Further provides are the sequences especially complementarity-determining region (CDR) sequences of antibodies disclosed.
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Guy L Cavet from Hillsborough, CA Get Report