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Guchen Yang

from Princeton, NJ
Age ~68
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Related to:
Jinrong Lin, 52Maryellen Hokanson, 64Andrew W Wu, 75Bing L LiangKitwah Chen, 71David Yang, 54Jie F Weng, 96Xun Y YangXunyi Yang
Connected to:
Abby Yang, 32Addison Yang, 43Aileen C Yang, 51Alexandria L Yang, 33Allerina Yang, 33Alyssa J Yang, 36Amee Yang, 31Amy Yang, 57Andrew Yang, 34Anna Yang, 40

Guchen Yang Phones & Addresses

  • 616 Princeton Kingston Rd, Princeton, NJ 08540 (609) 497-6439
  • 616 Princeton Kingston Rd #R, Princeton, NJ 08540 (609) 497-6439
  • 1 Makefield Rd, Morrisville, PA 19067 (215) 428-0533
  • Seattle, WA
  • Philadelphia, PA
  • Pullman, WA

Work

Position: Clerical/White Collar

Education

Degree: Associate degree or higher

Publications

Us Patents

Bsl3 Polypeptides

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US Patent:
7723479, May 25, 2010
Filed:
Sep 6, 2007
Appl. No.:
11/900026
Inventors:
Glen Eugene Mikesell - Pacifica CA, US
Han Chang - Princeton Junction NJ, US
Joshua N. Finger - Spring City PA, US
Guchen Yang - Princeton NJ, US
Robert James Peach - San Diego CA, US
Henry Shen - Princeton NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07K 14/705
US Classification:
530350
Abstract:
The present invention provides nucleic acids encoding B7-related factors that modulate the activation of immune or inflammatory response cells, such as T-cells. Also provided are expression vectors and fusion constructs comprising nucleic acids encoding B7-related polypeptides, including BSL1, BSL2, and BSL3. The present invention further provides isolated B7-related polypeptides, isolated fusion proteins comprising B7-related polypeptides, and antibodies that are specifically reactive with B7-related polypeptides, or portions thereof. In addition, the present invention provides assays utilizing B7-related nucleic acids, polypeptides, or peptides. The present invention further provides compositions of B7-related nucleic acids, polypeptides, fusion proteins, or antibodies that are useful for the immunomodulation of a human or animal subject.

High Throughput Assay For N-Sulfotransferase Activity Of Glucosaminyl N-Deacetylase/N-Sulfotransferases

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US Patent:
20030109501, Jun 12, 2003
Filed:
Oct 3, 2002
Appl. No.:
10/263970
Inventors:
Guchen Yang - Morrisville PA, US
Peter Kiener - Doylestown PA, US
Henry Shen - Princeton NJ, US
International Classification:
A61K031/66
C12Q001/34
US Classification:
514/102000, 435/018000
Abstract:
Assays for N-sulfotransferase activity of glucosaminyl N-deacetylase/N-sulfotransferases (NDSTs) include transferring a radiolabeled sulfate from a sulfate donor to a polysaccharide acceptor in the presence of an NDST enzyme to form a radiolabeled sulfated polysaccharide, the radiolabeled sulfated polysaccharide which when bound to a potentially scintillating particulate within an activating distance emits a detectable signal indicative of N-sulfotransferase activity. The assay provides high throughput assays for screening inhibitors that block N-sulfotransferase activity of an NDST. Specific compounds that inhibit N-sulfotransferase activity of an NDST and therapeutic uses of these compounds are disclosed.

Polynucleotide Encoding A Novel Pleckstrin Homology Domain And Proline Rich Domain Containing Adapter Protein, Pmn29

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US Patent:
20030157514, Aug 21, 2003
Filed:
Sep 4, 2002
Appl. No.:
10/234816
Inventors:
Joshua Finger - San Marcos CA, US
Juan Perez-Villar - Mercerville NJ, US
Reddy Rajashekar - Langhorne PA, US
Guchen Yang - Morrisville PA, US
Peter Kiener - Doylestown PA, US
International Classification:
C12Q001/68
G01N033/53
G01N033/567
C07H021/04
C12P021/02
C12N005/06
C07K014/47
US Classification:
435/006000, 435/069100, 435/320100, 435/325000, 530/350000, 536/023500, 435/007200
Abstract:
The present invention provides novel polynucleotides encoding PMN29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel PMN29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Polynucleotides Encoding B7-Related Nucleic Acid, Bsl2Vcvc-Ig

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US Patent:
20050208525, Sep 22, 2005
Filed:
Nov 22, 2004
Appl. No.:
10/994824
Inventors:
Glen Mikesell - Pacifica CA, US
Han Chang - Priceton Junction NJ, US
Joshua Finger - San Marcos CA, US
Guchen Yang - Morrisville PA, US
Robert Peach - San Diego CA, US
International Classification:
C12Q001/68
C07H021/04
C12N015/09
C07K014/74
US Classification:
435006000, 435069100, 435320100, 435325000, 530350000, 536023500
Abstract:
The present invention provides nucleic acids encoding B7-related factors that modulate the activation of immune or inflammatory response cells, such as T-cells. Also provided are expression vectors and fusion constructs comprising nucleic acids encoding B7-related polypeptides, including BSL1, BSL2, and BSL3. The present invention further provides isolated B7-related polypeptides, isolated fusion proteins comprising B7-related polypeptides, and antibodies that are specifically reactive with B7-related polypeptides, or portions thereof. In addition, the present invention provides assays utilizing B7-related nucleic acids, polypeptides, or peptides. The present invention further provides compositions of B7-related nucleic acids, polypeptides, fusion proteins, or antibodies that are useful for the immunomodulation of a human or animal subject.

B7-Related Nucleic Acids And Polypeptides Useful For Immunomodulation

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US Patent:
20060140937, Jun 29, 2006
Filed:
Feb 16, 2006
Appl. No.:
11/355735
Inventors:
Glen Mikesell - Pacifica CA, US
Han Chang - Princeton Junction NJ, US
Joshua Finger - San Marcos CA, US
Guchen Yang - Morrisville PA, US
Robert Peach - San Diego CA, US
International Classification:
C12Q 1/70
C12Q 1/68
C07H 21/02
A61K 39/395
A61K 39/42
C07K 14/16
C07K 14/705
US Classification:
424133100, 424160100, 435005000, 435006000, 435069300, 435320100, 435325000, 530350000, 530388300, 530387300, 536023100
Abstract:
The present invention provides nucleic acids encoding B7-related factors that modulate the activation of immune or inflammatory response cells, such as T-cells. Also provided are expression vectors and fusion constructs comprising nucleic acids encoding B7-related polypeptides, including BSL1, BSL2, and BSL3. The present invention further provides isolated B7-related polypeptides, isolated fusion proteins comprising B7-related polypeptides, and antibodies that are specifically reactive with B7-related polypeptides, or portions thereof. In addition, the present invention provides assays utilizing B7-related nucleic acids, polypeptides, or peptides. The present invention further provides compositions of B7-related nucleic acids, polypeptides, fusion proteins, or antibodies that are useful for the immunomodulation of a human or animal subject.

B7-Related Nucleic Acids And Polypeptides Useful For Immunomodulation

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US Patent:
20100125127, May 20, 2010
Filed:
Feb 7, 2008
Appl. No.:
12/069064
Inventors:
Glen E. Mikesell - Pacifica CA, US
Henry Shen - Princeton NJ, US
Han Chang - Princeton Junction NJ, US
Joshua N. Finger - Spring City PA, US
Guchen Yang - Princeton NJ, US
Robert James Peach - San Diego CA, US
International Classification:
C07K 7/06
C07K 7/08
C07K 5/06
C07K 5/08
C07K 5/10
C07K 14/00
C07K 16/00
C07C 211/00
US Classification:
530324, 530300, 530331, 530330, 530329, 530328, 530327, 530326, 530325, 5303871, 562553
Abstract:
The present invention provides nucleic acids encoding B7-related factors that modulate the activation of immune or inflammatory response cells, such as T-cells. Also provided are expression vectors and fusion constructs comprising nucleic acids encoding B7-related polypeptides, including BSL1, BSL2, and BSL3. The present invention further provides isolated B7-related polypeptides, isolated fusion proteins comprising B7-related polypeptides, and antibodies that are specifically reactive with B7-related polypeptides, or portions thereof. In addition, the present invention provides assays utilizing B7-related nucleic acids, polypeptides, or peptides. The present invention further provides compositions of B7-related nucleic acids, polypeptides, fusion proteins, or antibodies that are useful for the immunomodulation of a human or animal subject.

B7-Related Nucleic Acids And Polypeptides Useful For Immunomodulation

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US Patent:
20100136575, Jun 3, 2010
Filed:
Feb 5, 2010
Appl. No.:
12/701119
Inventors:
Glen Eugene Mikesell - Pacifica CA, US
Han Chang - Princeton Junction NJ, US
Joshua N. Finger - Spring City PA, US
Guchen Yang - Princeton NJ, US
Robert James Peach - San Deigo CA, US
Henry Shen - Princeton NJ, US
International Classification:
G01N 33/53
C07K 16/00
C12N 5/16
US Classification:
435 71, 5303879, 5303873, 435326
Abstract:
The present invention provides nucleic acids encoding B7-related factors that modulate the activation of immune or inflammatory response cells, such as T-cells. Also provided are expression vectors and fusion constructs comprising nucleic acids encoding B7-related polypeptides, including BSL1, BSL2, and BSL3. The present invention further provides isolated B7-related polypeptides, isolated fusion proteins comprising B7-related polypeptides, and antibodies that are specifically reactive with B7-related polypeptides, or portions thereof. In addition, the present invention provides assays utilizing B7-related nucleic acids, polypeptides, or peptides. The present invention further provides compositions of B7-related nucleic acids, polypeptides, fusion proteins, or antibodies that are useful for the immunomodulation of a human or animal subject.

B-7 Related Nucleic Acids And Polypeptides Useful For Immunomodulation

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US Patent:
20110294162, Dec 1, 2011
Filed:
May 20, 2010
Appl. No.:
12/783968
Inventors:
Glen E. Mikesell - Pacifica CA, US
Henry Shen - Princeton NJ, US
Han Chang - Princeton Junction NJ, US
Joshua N. Finger - Spring City PA, US
Guchen Yang - Princeton NJ, US
Robert James Peach - San Diego CA, US
International Classification:
C12P 21/00
C12N 1/19
C12N 1/21
C12N 1/15
C12N 15/62
C12N 5/10
US Classification:
435 696, 536 234, 4353201, 435 697, 435326, 435325, 435348, 435419, 4352523, 43525411, 4352542, 435366, 43525233, 43525231, 43525421, 435365, 435367, 435358, 4352544, 435357
Abstract:
The present invention provides nucleic acids encoding B7-related factors that modulate the activation of immune or inflammatory response cells, such as T-cells. Also provided are expression vectors and fusion constructs comprising nucleic acids encoding B7-related polypeptides, including BSL1, BSL2, and BSL3. The present invention further provides isolated B7-related polypeptides, isolated fusion proteins comprising B7-related polypeptides, and antibodies that are specifically reactive with B7-related polypeptides, or portions thereof. In addition, the present invention provides assays utilizing B7-related nucleic acids, polypeptides, or peptides. The present invention further provides compositions of B7-related nucleic acids, polypeptides, fusion proteins, or antibodies that are useful for the immunomodulation of a human or animal subject.
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Guchen Yang from Princeton, NJ, age ~68 Get Report