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Giorgio N Gaudiano

from Boulder, CO
Age ~94
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Also known as:
Giorgio P Gaudiano, Giorgio M Gaudiano
Phone and address:
1965 Kohler Dr, Boulder, CO 80305
(303) 499-6104
Related to:
Anthony G Limuti, 49
Connected to:
Brandon A Gaudiano, 47Christina M Gaudiana, 50Christie Gaudiano, 38Doreen J Gaudiana, 54Russell A Gaudiana, 80Jessica L Gaudiello, 34Josephine M Gaudiello, 84Mary A Gaudiello, 91Brice Gaudilliere, 47Alan K Gaudin, 63

Giorgio Gaudiano Phones & Addresses

  • 1965 Kohler Dr, Boulder, CO 80305 (303) 499-6104
  • Livingston Manor, NY
  • Essex, MA
  • New York, NY

Publications

Us Patents

Glutathione Derivatives Of Anthracyclines

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US Patent:
56461771, Jul 8, 1997
Filed:
May 2, 1995
Appl. No.:
8/432836
Inventors:
Tad H. Koch - Boulder CO
Giorgio Gaudiano - Boulder CO
Assignee:
Board of Regents of The University of Colorado - Boulder CO
Consiglio Nazionale Delle Richerche - Rome
International Classification:
C07D31904
C07D31908
C07D 5022
US Classification:
514452
Abstract:
Disclosed herein are new anthracyclines which are derived from conjugation with glutathione, for example from conjugation of adriamycin, daunomycin and menogaril with glutathione: compounds 7 I, 7 II, 8 I, 8 II, 9 I and 9II, are obtained by reduction of the anthracycline followed by reaction of the reduced product with glutathione in aqueous (H. sub. 2 O or D. sub. 2 O) or organic solvent. The invention also provides salts of these glutathione derivatives, particularly salts formed from anthracycline glutathione anions with anthracycline cations. These anthracycline derivatives are useful as antibiotics, as antitumor agents, and in the treatment of AIDS. These derivatives are particularly useful in the treatment of cancer when multiple drug resistance is present.

Oxomorpholinyl Dimer And Rescue Of Anthracycline And Mitomycin C Damage

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US Patent:
46329226, Dec 30, 1986
Filed:
Oct 24, 1985
Appl. No.:
6/791120
Inventors:
Steven D. Averbuch - Rockville MD
Nicholas R. Bachur - Towson MD
Giorgio Gaudiano - Boulder CO
Tad H. Koch - Boulder CO
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
University of Colorado Foundation, Inc. - CO
International Classification:
A61K 31535
C07D26532
US Classification:
514236
Abstract:
The present invention discloses a bi(3,5-dimethyl-5-hydroxymethyl-2-oxomorpholin-3-yl) compound and its efficacy as a rescue agent against anthracycline and mitomycin C induced tissue damage. A method of synthesizing said compound has also been described.
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Giorgio N Gaudiano from Boulder, CO, age ~94 Get Report