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Gerald P Linette

from West Chester, PA
Age ~95
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Related to:
Linet N Gelpi, 29Elsa Thompson Rodriguez, 79John B Linette, 60Neil F Gallagher, 68Christine T Gallagher, 76Mary B LinetteJosephine S LinetteJoseph S LinetteEileen F GallagherEmily K Maisch, 64Mary GallagherMargaret L Gallagher, 62
Connected to:
Jason A Linetzky, 53John C Lineweaver, 74Eleanor J Liney, 92Grace K Liney, 82Patrick Liney, 49Rosemarie Linfante, 34Donna K Linfield, 64Lance W Linfoot, 75Christie R Linford, 37Earl J Linford, 78

Gerald Linette Phones & Addresses

  • 1591 Ulster Pl, West Chester, PA 19380 (610) 918-4912
  • Indialantic, FL
  • 265 Forrest Rd, Merion Station, PA 19066 (610) 667-4733
  • Philadelphia, PA

Emails

g***[email protected]

Professional Records

License Records

Gerald P. Linette

Address:
Philadelphia, PA 19104
License #:
MD458447 - Active
Category:
Medicine
Type:
Medical Physician and Surgeon

Medicine Doctors

Gerald Linette Photo 1

Gerald P. Linette

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Specialties:
Medical Oncology
Work:
Washington University PhysiciansSiteman Cancer Center
4921 Parkview Pl STE A, Saint Louis, MO 63110
(314) 362-7578 (phone), (314) 362-7086 (fax)
Education:
Medical School
Georgetown University School of Medicine
Graduated: 1990
Procedures:
Bone Marrow Biopsy
Chemotherapy
Conditions:
Anemia
Breast Neoplasm, Malignant
Gastric Cancer
Hodgkin's Lymphoma
Iron Deficiency Anemia
Languages:
Chinese
English
Spanish
Description:
Dr. Linette graduated from the Georgetown University School of Medicine in 1990. He works in Saint Louis, MO and specializes in Medical Oncology. Dr. Linette is affiliated with Barnes Jewish Hospital and Barnes Jewish West County Hospital.

Publications

Us Patents

Personalized Cancer Vaccines And Methods Therefor

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US Patent:
20170202939, Jul 20, 2017
Filed:
Mar 14, 2017
Appl. No.:
15/458149
Inventors:
- Saint Louis MO, US
Gerald LINETTE - Philadelphia PA, US
Elaine MARDIS - Troy IL, US
Vincent MAGRINI - Saint Louis MO, US
International Classification:
A61K 39/00
G01N 33/569
C12N 5/0784
C12Q 1/68
Abstract:
Methods of cane r treatment based, on personalized vaccines are disclosed. Individual amino acid substitutions from tumors are revealed using whole genome sequencing, and identified as neoantigens silico. Peptide sequences are then tested in vitro for ability to bind HLA molecules and to be presented to CD8+ T-cells. A vaccine is formed using neoantigen peptides and an adjuvant or dendritic cells (DC) autologous to a subject. In the latter, autologous DC are matured and contacted with the neoantigen peptides. The DC are then administered to the subject. PBMC are then obtained from the subject, and CD8+ T cells specific to the neoantigens are cultured and enriched. Enriched T-cells are then administered to the subject to treat cancer. Treatment resulted in tumor regression in mice bearing human melanomas, and complete or partial responses were observed in human patients.
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Gerald P Linette from West Chester, PA, age ~95 Get Report