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George Axford Phones & Addresses

  • Wishram, WA
  • Belmont, CA
  • 1167 Cervantes Way, Pacifica, CA 94044 (650) 355-4961 (650) 341-9520
  • 447 Norfolk Dr, Pacifica, CA 94044 (650) 355-4961
  • 2727 Edison St, San Mateo, CA 94403 (650) 341-9520
  • 2727 Edison St #116, San Mateo, CA 94403 (650) 341-9520
  • 1178 Portola Meadows Rd #154, Livermore, CA 94551 (510) 881-0868
  • 1192 Portola Meadows Rd, Livermore, CA 94551
  • Palo Alto, CA
  • San Carlos, CA
  • 1167 Cervantes Way, Pacifica, CA 94044

Work

Position: Craftsman/Blue Collar

Education

Degree: High school graduate or higher

Resumes

Resumes

George Axford Photo 1

George Axford

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George Axford Photo 2

Staff Engineer

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Location:
San Francisco Bay Area
Industry:
Biotechnology

Publications

Us Patents

Apparatus And Methods For Dispersing Dry Powder Medicaments

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US Patent:
6543448, Apr 8, 2003
Filed:
May 30, 2000
Appl. No.:
09/583300
Inventors:
Adrian E. Smith - Belmont CA
John D. Burr - Redwood City CA
Jeffrey W. Etter - Castro Valley CA
George S. Axford - Menlo Park CA
Jack M. Anthony - Palo Alto CA
Assignee:
Inhale Therapeutic Systems, Inc. - San Carlos CA
International Classification:
A61M 1500
US Classification:
12820315, 12820321
Abstract:
A method for aerosolizing a powdered medicament comprises coupling a powder inlet end of a feed tube with a penetration in a receptacle containing the powder. Powder is drawn upward through the tube and dispersed in a high pressure gas stream flowing past a portion of the feed tube. Apparatus comprise the feed tube mounted within a base enclosure proximate a holder for one or more receptacles, which may be in the form of a cartridge containing a plurality of receptacles formed in a continuous web. The cartridge may be reciprocated relative to the feed tube and a separate piercing mechanism in order to sequentially piercing the receptacle and thereafter couple the feed tube through the resulting penetration for extracting the powder. Alternatively, penetration(s) through the receptacle may be formed as the feed tube is coupled, or some penetrations formed prior to coupling with other penetrations formed at the time of coupling.

Dry Powder Dispersing Apparatus And Methods For Their Use

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US Patent:
6546929, Apr 15, 2003
Filed:
Jun 4, 2001
Appl. No.:
09/873946
Inventors:
John D. Burr - Redwood City CA
Adrian E. Smith - Belmont CA
Randy K. Hall - Mountain View CA
Herman Snyder - Belmont CA
Carlos Schuler - Cupertino CA
George S. Axford - San Mateo CA
Charles Ray - Foster City CA
Assignee:
Inhale Therapeutic Systems, Inc. - San Carlos CA
International Classification:
A61M 1500
US Classification:
12820315, 12820321
Abstract:
The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position. The second interlock remains engaged if the receptacle is only partially inserted into the carriage assembly.

Dry Powder Dispersing Apparatus And Methods For Their Use

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US Patent:
6901929, Jun 7, 2005
Filed:
Dec 19, 2002
Appl. No.:
10/327633
Inventors:
John D. Burr - Redwood City CA, US
Adrian E. Smith - Belmont CA, US
Randy K. Hall - Dublin GA, US
Herman Snyder - Pacifica CA, US
Carlos Schuler - Cupertino CA, US
George S. Axford - Pacifica CA, US
Charles Ray - Brentwood CA, US
Assignee:
Nektar Therapeutics - San Carlos CA
International Classification:
A61M015/00
US Classification:
12820315, 12820321
Abstract:
The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position. The second interlock remains engaged if the receptacle is only partially inserted into the carriage assembly.

Dry Powder Dispersing Apparatus And Methods For Their Use

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US Patent:
7422013, Sep 9, 2008
Filed:
Mar 9, 2005
Appl. No.:
11/076418
Inventors:
John D. Burr - Redwood City CA, US
Adrian E. Smith - Emerald Hills CA, US
George S. Axford - Pacifica CA, US
Assignee:
Nektar Therapeutics - San Carlos CA
International Classification:
A61M 11/00
A61M 15/00
US Classification:
12820023, 12820321
Abstract:
The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position. The second interlock remains engaged if the receptacle is only partially inserted into the carriage assembly.

Dry Powder Dispersing Apparatus And Methods For Their Use

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US Patent:
8161969, Apr 24, 2012
Filed:
Mar 21, 2008
Appl. No.:
12/077877
Inventors:
John D. Burr - Redwood City CA, US
Adrian E. Smith - Emerald Hills CA, US
Randy K. Hall - Dublin GA, US
Herm Snyder - Pacifica CA, US
Carlos A. Schuler - Cupertino CA, US
George S. Axford - Pacifica CA, US
Charles Ray - Brentwood CA, US
Assignee:
Novartis AG - Basel
International Classification:
A61M 15/00
A61M 16/00
US Classification:
12820321, 12820315, 12820312
Abstract:
The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position. The second interlock remains engaged if the receptacle is only partially inserted into the carriage assembly.

Powder Dispersion Apparatus, Method Of Making And Using The Apparatus, And Components That Can Be Used On The Apparatus And Other Devices

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US Patent:
8573197, Nov 5, 2013
Filed:
Oct 25, 2007
Appl. No.:
12/447045
Inventors:
George S Axford - Pacifica CA, US
Mark Glusker - San Mateo CA, US
William W Alston - San Jose CA, US
John Palmer-Felgate - Horsham, GB
Jonathan Wilkins - Cambridge, GB
Willard R Foss - Thousand Oaks CA, US
Nagaraja Rao - San Leandro CA, US
Mark Postich - Menlo Park CA, US
Neeraj R Pakala - Cupertino CA, US
David S Maltz - San Francisco CA, US
Keith Ung - Belmont CA, US
Assignee:
Novartis AG - Basel
International Classification:
A61M 11/00
US Classification:
12820014, 12820315, 12820321
Abstract:
Methods and apparatuses for the pulmonary delivery of a composition, such as methods and apparatuses for dispersing dry powder medicaments for inhalation by a patient. Elements or aspects of the apparatuses, including receptacle puncturing mechanisms, deoccluding devices, receptacle impacting devices, and receptacle lock devices or systems.

Apparatus And Method For Dispersing Dry Powder Medicaments

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US Patent:
20030183229, Oct 2, 2003
Filed:
Feb 6, 2003
Appl. No.:
10/360599
Inventors:
Adrian Smith - Belmont CA, US
John Burr - Redwood City CA, US
Jeffrey Etter - Castro Valley CA, US
George Axford - Pacifica CA, US
Jack Anthony - Palo Alto CA, US
Assignee:
INHALE THERAPEUTIC SYSTEMS, a corporation of the State of California - Palo Alto CA
International Classification:
A61M015/00
A61M016/10
US Classification:
128/203120, 128/203210
Abstract:
A method for aerosolizing a powdered medicament comprises coupling a powder inlet end of a feed tube with a penetration in a receptacle containing the powder. Powder is drawn upward through the tube and dispersed in a high pressure gas stream flowing past a portion of the feed tube. Apparatus comprise the feed tube mounted within a base enclosure proximate a holder for one or more receptacles, which may be in the form of a cartridge containing a plurality of receptacles formed in a continuous web. The cartridge may be reciprocated relative to the feed tube and a separate piercing mechanism in order to sequentially piercing the receptacle and thereafter couple the feed tube through the resulting penetration for extracting the powder. Alternatively, penetration(s) through the receptacle may be formed as the feed tube is coupled, or some penetrations formed prior to coupling with other penetrations formed at the time of coupling.

Powder Dispersion Apparatus, Method Of Making And Using The Apparatus, And Components That Can Be Used On The Apparatus And Other Devices

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US Patent:
20140034052, Feb 6, 2014
Filed:
Oct 15, 2013
Appl. No.:
14/053946
Inventors:
Mark GLUSKER - San Mateo CA, US
George S AXFORD - Pacifica CA, US
William W Alston - San Jose CA, US
John PALMER-FELGATE - Horsham, GB
Jonathan WILKINS - Cambridge, GB
Willard R FOSS - Thousand Oaks CA, US
Nagaraja Rao - San Leandro CA, US
Mark POSTICH - Menlo CA, US
Nagaraja RAO - San Leandro CA, US
Neeraj PAKALA - Cupertino CA, US
David S MALTZ - San Francisco CA, US
Keith UNG - Belmont CA, US
Assignee:
NOVARTIS AG - Basel
International Classification:
A61M 15/00
US Classification:
12820315
Abstract:
Methods and apparatuses for the pulmonary delivery of a composition, such as methods and apparatuses for dispersing dry powder medicaments for inhalation by a patient. Elements or aspects of the apparatuses, including receptacle puncturing, mechanisms, deoccluding devices, receptacle impacting devices, and receptacle lock devices or systems.
George S Axford from Wishram, WA, age ~63 Get Report