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Gaylen M Zentner

from Salt Lake City, UT
Age ~73
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Related to:
Nellie M ZentnerYork N Zentner, 59Michelle Zentner, 38Dean ZentnerBrooke Zentner, 45J Dean ZentnerSteven J Zentner, 37Annalisa Havens, 42Emily B Zentner, 41Darryl Marsh, 45Elizabeth S Zentner, 69
Connected to:
Brandon Zentner, 35Diane K Zentner, 68Jeremy M Zentner, 47Karl A Zentner, 92Lacey M Zentner, 42Alison M Zentz, 40Andrea K Zentz, 37Anthony Zentz, 37Kevin B Zentz, 71Lisa A Zentz, 64

Gaylen Zentner Phones & Addresses

  • 6312 Colleton Cir, Salt Lake Cty, UT 84121 (801) 277-5524
  • Salt Lake City, UT
  • Brooklyn, NY
  • Sandy, UT
  • Lawrence, KS
  • Kew Gardens, NY

Professional Records

License Records

Gaylen M Zentner

Address:
Salt Lake City, UT
License #:
142658-1701 - Active
Category:
Pharmacy
Issued Date:
Jan 1, 1911
Expiration Date:
Sep 30, 2017
Type:
Pharmacist

Gaylen M Zentner

Address:
Salt Lake City, UT
License #:
142658-8911 - Active
Category:
Pharmacy
Issued Date:
Jan 1, 1911
Expiration Date:
Sep 30, 2017
Type:
Pharmacist Controlled Substance

Resumes

Resumes

Gaylen Zentner Photo 1

Vp Cmc R&D Myrexis, Inc. (Formerly Myriad Pharmaceuticals, Inc.)

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Position:
VP Chemistry, Manufacturing, and Controls Research and Development at Myrexis, Inc.
Location:
Greater Salt Lake City Area
Industry:
Pharmaceuticals
Work:
Myrexis, Inc. since Apr 2002
VP Chemistry, Manufacturing, and Controls Research and Development
MacroMed, Inc. Aug 1997 - Apr 2002
Executive Vice President, Pharmaceutical Research and Development
Sarcos Feb 1995 - Aug 1997
Director, Drug Delivery
Merck & Co. Jun 1987 - Feb 1995
Director, Controlled Release (INTERx Division)
Education:
University of Utah 1975 - 1979
PhD, Pharmaceutics
Gaylen Zentner Photo 2

Vice President At Myriad Pharmaceuticals, Inc

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Location:
Greater Salt Lake City Area
Industry:
Pharmaceuticals

Business Records

Name / Title
Company / Classification
Phones & Addresses
Gaylen M. Zentner
Principal
COMPREHENSIVE CMC OUTSOURCING, LLC
Business Services at Non-Commercial Site · Nonclassifiable Establishments
6312 S Colleton Cir, Salt Lake City, UT 84121

Publications

Us Patents

Polymer Blends That Swell In An Acidic Environment And Deswell In A Basic Environment

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US Patent:
6537584, Mar 25, 2003
Filed:
Nov 9, 2000
Appl. No.:
09/710403
Inventors:
Gaylen M. Zentner - Salt Lake City UT
Jong-Seok Bark - Salt Lake City UT
Feng Liu - Salt Lake City UT
Assignee:
MacroMed, Inc. - Sandy UT
International Classification:
A61K 950
US Classification:
424499, 424484, 424486, 424488, 424489, 424502, 514772, 5147721, 5147722, 5147723, 5147726
Abstract:
A polymer blend is prepared by dissolving chitosan and a second polymer in an acidic aqueous solution to form an aqueous polymer blend, dehydrating said aqueous polymer blend, and recovering said polymer blend. The second polymer may be selected from the group consisting of polyether glycols including polyethylene glycols; cellulose esters including cellulose acetate; poloxamers; polysaccharides including dextran and guar; polyvinylpyrrolidones; polyvinyl alcohols; and mixtures or copolymers thereof. These polymer blends swell in an acidic environment and deswell in a more neutral or basic environment. This technology is valuable for the dispensing of biologically active material or drugs into a surrounding environment, especially the environment as is found in the gastrointestinal tract. Since the various polymer blends of the present invention are not covalently or ionically crosslinked, but are physically combined, each polymer in the physical blend maintains its original chemical structure, and therefore, is safe for oral administration.

Bioactive Agent Delivering System Comprised Of Microparticles Within A Biodegradable To Improve Release Profiles

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US Patent:
6589549, Jul 8, 2003
Filed:
Jul 13, 2001
Appl. No.:
09/906041
Inventors:
Chung Shih - Salt Lake City UT
Gaylen Zentner - Salt Lake City UT
Assignee:
Macromed, Incorporated - Sandy UT
International Classification:
A61F 200
US Classification:
424426, 424486, 424489, 424501, 5147723
Abstract:
A composition and method for releasing a bio-active agent or a drug within a biological environment in a controlled manner is disclosed. The composition is a dual phase polymeric agentâdelivery composition comprising a continuous biocompatible gel phase, a discontinuous particulate phase comprising defined microparticles and an agent to be delivered. A microparticle containing a bio-active agent is releasably entrained within a biocompatible polymeric gel matrix. The bioactive agent release may be contained in the microparticle phase alone or in both the microparticles and the gel matrix. The release of the agent is prolonged over a period of time, and the delivery may be modulated and/or controlled. In addition, a second agent may be loaded in some of the microparticles and/or the gel matrix.

Pla/Plga Oligomers Combined With Block Copolymers For Enhancing Solubility Of A Drug In Water

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US Patent:
6592899, Jul 15, 2003
Filed:
Oct 3, 2001
Appl. No.:
09/971082
Inventors:
Kirk Dee Fowers - Layton UT
Gaylen M. Zentner - Salt Lake City UT
Chung Shih - Sandy UT
Assignee:
Macromed Incorporated - Sandy UT
International Classification:
A61K 914
US Classification:
424486, 424426, 424444, 424430, 424434, 424449, 424484, 525411, 525413, 525415
Abstract:
Polymeric compositions having improved capability of solubilizing a drug in a hydrophilic environment to form a solution, comprising: a biodegradable polyester oligomer; and biodegradable AB-type, ABA-type, or BAB-type block copolymers are disclosed. The copolymers are comprised of about 50. 1 to 65% by weight of a biodegradable, hydrophobic A polymer block comprising a biodegradable polyester, and about 35 to 49. 9% by weight of a hydrophilic B polymer block comprising a polyethylene glycol (PEG), and wherein the block copolymer has a weight averaged molecular weight of between 2400 to 4999. The biodegradable polyester oligomer of said composition is within a range of 0. 01% to 30% by weight of the total polymer mixture, and the content of the biodegradable AB-type, ABA-type, or BAB-type block copolymer is within a range of 70% to 99. 99% by weight of the total polymer mixture.

Polymer Blends That Swell In An Acidic Environment And Deswell In A Basic Environment

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US Patent:
6730327, May 4, 2004
Filed:
Dec 20, 2002
Appl. No.:
10/327457
Inventors:
Gaylen M. Zentner - Salt Lake City UT
Jong-Seok Bark - Salt Lake City UT
Feng Liu - Salt Lake City UT
Assignee:
MacroMed, Inc. - Sandy UT
International Classification:
A61K 914
US Classification:
424489, 424484, 424486, 424488, 424499, 424501, 514772, 5147721, 5147722, 5147723
Abstract:
A polymer blend is prepared by dissolving chitosan and a second polymer in an acidic aqueous solution to form an aqueous polymer blend, dehydrating said aqueous polymer blend, and recovering said polymer blend. The second polymer may be selected from the group consisting of polyether glycols including polyethylene glycols; cellulose esters including cellulose acetate; poloxamers; polysaccharides including dextran and guar; polyvinylpyrrolidones; polyvinyl alcohols; and mixtures or copolymers thereof. These polymer blends swell in an acidic environment and deswell in a more neutral or basic environment. This technology is valuable for the dispensing of biologically active material or drugs into a surrounding environment, especially the environment as is found in the gastrointestinal tract. Since the various polymer blends of the present invention are not covalently or ionically crosslinked, but are physically combined, each polymer in the physical blend maintains its original chemical structure, and therefore, is safe for oral administration.

Proteins Deposited Onto Sparingly Soluble Biocompatible Particles For Controlled Protein Release Into A Biological Environment From A Polymer Matrix

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US Patent:
6998137, Feb 14, 2006
Filed:
Apr 5, 2001
Appl. No.:
09/827100
Inventors:
Chung Shih - Sandy UT, US
Gaylen Zentner - Salt Lake City UT, US
Assignee:
MacroMed, Inc. - Sandy UT
International Classification:
A61F 2/00
A61F 9/14
A61F 9/50
A61F 47/30
A61K 31/74
A61K 38/00
US Classification:
424426, 424 7808, 424423, 424486, 424489, 424501, 514 2
Abstract:
The present invention relates to compositions and methods for the modulated release of one or more proteins or peptides. The composition is comprised of a biocompatible polymeric matrix, a protein and/or peptide, and a sparingly water-soluble or essentially insoluble particle. The protein is deposited by adsorption or some other mechanism onto the sparingly water-soluble biocompatible particle wherein the protein-particle combination is dispersed within the polymeric matrix. The deposition of the protein onto the particle acts to modulate the release of the protein or peptide from dosage forms including long-acting dosage systems.

Polymer Blends That Swell In An Acidic Environment And Deswell In A Basic Environment

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US Patent:
7182957, Feb 27, 2007
Filed:
Dec 20, 2002
Appl. No.:
10/327814
Inventors:
Gaylen M. Zentner - Salt Lake City UT, US
Jong-Seok Bark - Salt Lake City UT, US
Feng Liu - Salt Lake City UT, US
Assignee:
Macromed, Inc. - West Valley City UT
International Classification:
A61K 9/48
US Classification:
424451, 424485, 424486, 424488, 424499, 424500, 424501
Abstract:
A polymer blend is prepared by dissolving chitosan and a second polymer in an acidic aqueous solution to form an aqueous polymer blend, dehydrating said aqueous polymer blend, and recovering said polymer blend. The second polymer may be selected from the group consisting of polyether glycols including polyethylene glycols; cellulose esters including cellulose acetate; poloxamers; polysaccharides including dextran and guar; polyvinylpyrrolidones; polyvinyl alcohols; and mixtures or copolymers thereof. These polymer blends swell in an acidic environment and deswell in a more neutral or basic environment. This technology is valuable for the dispensing of biologically active material or drugs into a surrounding environment, especially the environment as is found in the gastrointestinal tract. Since the various polymer blends of the present invention are not covalently or ionically crosslinked, but are physically combined, each polymer in the physical blend maintains its original chemical structure, and therefore, is safe for oral administration.

Biodegradable Block Copolymeric Compositions For Drug Delivery

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US Patent:
7649023, Jan 19, 2010
Filed:
Jun 28, 2002
Appl. No.:
10/186462
Inventors:
Chung Shih - Sandy UT, US
Gaylen M. Zentner - Salt Lake City UT, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 47/00
A61K 31/335
C07D 305/00
A61F 2/00
A01N 25/00
A01N 43/02
US Classification:
5147721, 424424, 424425, 424426, 514449, 514785, 549511
Abstract:
An improved drug delivery composition and method of use is disclosed. The composition comprises one or more biodegradable block copolymer drug carriers; and a reconstitution enhancing and enabling agent comprising polyethylene glycol (PEG), a PEG derivative or a mixture of PEG and a PEG derivative. The composition can be administered as is or after being be dissolved or rapidly reconstituted in an aqueous vehicle to afford a homogeneous solution or uniform colloidal systems.

Biodegradable Block Copolymeric Compositions For Drug Delivery

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US Patent:
8642666, Feb 4, 2014
Filed:
Jun 24, 2009
Appl. No.:
12/490968
Inventors:
Chung Shih - Sandy UT, US
Gaylen M. Zentner - Salt Lake City UT, US
Assignee:
Protherics Salt Lake City, Inc. - West Valley City UT
International Classification:
A61K 47/14
A61K 31/335
C07D 305/00
A61F 2/00
A01N 25/00
A01N 43/02
US Classification:
5147721, 424424, 424425, 424426, 424486, 514449, 514511, 514785
Abstract:
An improved drug delivery composition and method of use is disclosed. The composition comprises one or more biodegradable block copolymer drug carriers; and a reconstitution enhancing and enabling agent comprising polyethylene glycol (PEG), a PEG derivative or a mixture of PEG and a PEG derivative. The composition can be administered as is or after being be dissolved or rapidly reconstituted in an aqueous vehicle to afford a homogeneous solution or uniform colloidal systems.
Control profile
Gaylen M Zentner from Salt Lake City, UT, age ~73 Get Report