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Gargey B Yagnik

from Hopkinton, MA
Age ~43
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Related to:
James R Walker, 48Christina Y Vansickle, 52James A Walker, 58
Connected to:
Anant M Yagnik, 48Gunjan Yagnik, 31Khyati B Yagnik, 40Manisha D Yagnik, 55Rekha P Yagnik, 79Evelyn L Yagnow, 48Michael R Yago, 38Paul C Yago, 56Ruth A Yago, 85Tracy M Yago, 52

Gargey Yagnik Phones & Addresses

  • Hopkinton, MA
  • Framingham, MA
  • Ames, IA
  • North Hollywood, CA

Resumes

Resumes

Gargey Yagnik Photo 1

Senior Scientist And Director Of Mass Spectrometry

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Location:
Ames, IA
Industry:
Biotechnology
Work:
Ambergen
Senior Scientist and Director of Mass Spectrometry
Ambergen Jan 2017 - Sep 2019
Scientist, Maldi-Imaging Mass Spectrometry, Proteomics and Drug Discovery
Sanofi Genzyme Sep 2015 - Jan 2017
Postdoctoral Researcher, Maldi- Imaging Mass Spectrometry, Dmpk
Iowa State University Aug 2011 - Aug 2015
Graduate Researcher and Teaching Assistant
California State University, Los Angeles Dec 2008 - Jul 2011
Graduate Research and Teaching Assistant
Education:
Iowa State University 2011 - 2015
Doctorates, Doctor of Philosophy, Philosophy, Chemistry California State University, Los Angeles 2008 - 2011
Master of Science, Masters, Chemistry Gujarat University 2002 - 2004
Master of Science, Masters, Organic Chemistry
Skills:
Hplc
Chemistry
Mass Spectrometry
Analytical Chemistry
Lc Ms
Spectroscopy
Gas Chromatography
Uv/Vis
Laboratory
Chromatography
Organic Chemistry
Gc Ms
R&D
Biochemistry
Pharmaceutical Industry
Validation
Maldi Msi
Maldi Ms
Nanoparticles
Uv/Vis Spectroscopy
Method Development
Fluorescence Spectroscopy
High Performance Liquid Chromatography
Lesa Ms
Laboratory Skills
Ir Spectroscopy
Liquid Chromatography Mass Spectrometry
Scanning Electron Microscopy
Interests:
Children
Economic Empowerment
Environment
Education
Poverty Alleviation
Science and Technology
Disaster and Humanitarian Relief
Human Rights
Animal Welfare
Health
Languages:
English
Hindi
Gujarati
Gargey Yagnik Photo 2

Gargey Yagnik

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Location:
United States

Publications

Us Patents

Novel Photocleavable Mass-Tags For Multiplexed Mass Spectrometric Imaging Of Tissues Using Biomolecular Probes

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US Patent:
20220365097, Nov 17, 2022
Filed:
Jul 12, 2022
Appl. No.:
17/862990
Inventors:
- Watertown MA, US
Gargey Yagnik - Hopkinton MA, US
Kenneth J. Rothschild - Newton MA, US
International Classification:
G01N 33/68
C07C 271/20
C12Q 1/6841
Abstract:
The field of this invention relates to immunohistochemistry (IHC) and in situ hybridization (ISH) for the targeted detection and mapping of biomolecules (e.g., proteins and miRNAs) in tissues or cells for example, for research use and for clinical use such by pathologists (e.g., biomarker analyses of a resected tumor or tumor biopsy). In particular, the use of mass spectrometric imaging (MSI) as a mode to detect and map the biomolecules in tissues or cells for example. More specifically, the field of this invention relates to photocleavable mass-tag reagents which are attached to probes such as antibodies and nucleic acids and used to achieve multiplex immunohistochemistry and in situ hybridization, with MSI as the mode of detection/readout. Probe types other than antibodies and nucleic acids are also covered in the field of invention, including but not limited to carbohydrate-binding proteins (e.g., lectins), receptors and ligands. Finally, the field of the invention also encompasses multi-omic MSI procedures, where MSI of photocleavable mass-tag probes is combined with other modes of MSI, such as direct label-free MSI of endogenous biomolecules from the biospecimen (e.g., tissue), whereby said biomolecules can be intact or digested (e.g., chemically digested or by enzyme).

Novel Photocleavable Mass-Tags For Multiplexed Mass Spectrometric Imaging Of Tissues Using Biomolecular Probes

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US Patent:
20220365098, Nov 17, 2022
Filed:
Jul 13, 2022
Appl. No.:
17/863928
Inventors:
- Watertown MA, US
Gargey Yagnik - Hopkinton MA, US
Kenneth J. Rothschild - Newton MA, US
International Classification:
G01N 33/68
C07C 271/20
C12Q 1/6841
Abstract:
The field of this invention relates to immunohistochemistry (IHC) and in situ hybridization (ISH) for the targeted detection and mapping of biomolecules (e.g., proteins and miRNAs) in tissues or cells for example, for research use and for clinical use such by pathologists (e.g., biomarker analyses of a resected tumor or tumor biopsy). In particular, the use of mass spectrometric imaging (MSI) as a mode to detect and map the biomolecules in tissues or cells for example. More specifically, the field of this invention relates to photocleavable mass-tag reagents which are attached to probes such as antibodies and nucleic acids and used to achieve multiplex immunohistochemistry and in situ hybridization, with MSI as the mode of detection/readout. Probe types other than antibodies and nucleic acids are also covered in the field of invention, including but not limited to carbohydrate-binding proteins (e.g., lectins), receptors and ligands. Finally, the field of the invention also encompasses multi-omic MSI procedures, where MSI of photocleavable mass-tag probes is combined with other modes of MSI, such as direct label-free MSI of endogenous biomolecules from the biospecimen (e.g., tissue), whereby said biomolecules can be intact or digested (e.g., chemically digested or by enzyme).
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Gargey B Yagnik from Hopkinton, MA, age ~43 Get Report