Gaddam N Goud

18400 Polynesian Ln, Boyds, MD 20841

Biotechnology

Lmi
Senior Consultant, Science and Technology
Noblis Esi Llc/The Tauri Group May 2014 - Feb 2019
Process Advisor
Vaccine and Biotherapeutics Process Development Technology Transfer and Cgmp Manufacturing 2012 - 2014
Consultant and Contractor
Yisheng Us Biopharma 2010 - 2011
Director, Downstream Process Development
Sabin Vaccine Institute 2002 - 2010
Director, Process Development and Technology Transfer and Research Professor

University of Maryland Baltimore County 1996 - 1997
Postdoctoral Research, Protein engineering (Phage display), expression, purification & characterization University of Pittsburgh 1994 - 1996
Postdoctoral Research, Protein engineering (Phage Display), expression & purification University of Arizona 1993 - 1993
Postdoctoral Research, Protein Purification Universite de technologie de Compiegne, France 1990 - 1990
Visiting Scientist, Protein Purification Osmania University, India.
Ph.D, Chemistry (Bioinorganic) Osmania University, India.
Master of Science (M.Sc.), Chemistry (Bioinorganic) Osmania University, India.
Bachelor of Science (B.Sc.), Chemistry & Biology

Protein Purification
Technology Transfer
Vaccines
Protein Expression
Biotechnology
Downstream Processing
Biopharmaceuticals
Phage Display
Product Development
Chromatography
Molecular Biology
Ind
Gmp
Fermentation Technology
Cell Culture
Process Development
Protein Engineering
Team Building
Team Leadership
Hplc
Sds Page
Western Blotting
Elisa
Biochemistry
Sop
Glp
Fermentation
Good Laboratory Practice
High Performance Liquid Chromatography
Monoclonal Antibodies
Standard Operating Procedure
Process Simulation
Viral Vaccines
Bioinorganic Chemistry
Cgmp
Design of Experiments
Enzyme Kinetics
Enzyme Assays
Bpr
Cmc
Document Review
Literature Reviews
Sbir Grant Review

Photograph
Cooking
Exercise
Electronics
Traveling
Outdoors
Home Improvement
International Traavel
Reading
Music
Sports
Travel
Movies
Home Decoration

English

Yisheng US Biopharma, Inc.
Gaithersburg, MD
Mar 2010 to Jul 2011
Director, Downstream Process Development
Albert B. Sabin Vaccine Institute/Human Hookworm Vaccine Initiative/GWU
Washington, DC
Nov 2002 to Feb 2010
Director, Downstream Process Development & Research Professor, Departments of Microbiology, Immunology, Tropical Medicine & Biochemistry and Molecular Biology
EntreMed, Inc.
Rockville, MD
Apr 2002 to Aug 2002
Research Scientist
University of Maryland Baltimore County
Baltimore, MD
Aug 1997 to Feb 2001
Assistant Research Professor
Osmania University
Hyderabad, Andhra Pradesh
Mar 1984 to Jan 1998
Assistant/Associate Professor of Chemistry
University of Maryland Baltimore County
Baltimore, MD
Aug 1996 to Jul 1997
Postdoctoral Research Associate
University of Pittsburgh
Pittsburgh, PA
Jan 1994 to Jul 1996
Postdoctoral Research Associate
University of Arizona
Tucson, AZ
Jan 1993 to Dec 1993
Postdoctoral Research Associate
Universite de Technologie de Compiegne
Compigne (60)
Jun 1990 to Aug 1990
Visiting Scientist

University of Arizona (Tucson), University of Pittsburgh (Pittsburgh) and University of Maryland Baltimore County (Baltimore)
USA
1993 to 1997
Postdoctoral Research in Protein Engineering (Phage Display), Expression, Purification and Characterization
Osmania University
Hyderabad, Andhra Pradesh
1976 to 1983
Ph.D & M.Sc in Chemistry (Bioinorganic)
Osmania University
Hyderabad, Andhra Pradesh
Jan 1973 to Jan 1976
B.Sc in Biology & Chemistry

* Extensive experience in the development and optimization of scalable and robust fermentation processes (using Bioflo 3000 and fermentors with Biocommand software). Extensive experience in using micro, ultra and crossflow filtration systems under GLP and GMP guidelines. * Experienced in the development and optimization of scalable and robust purification processes of recombinant antigens using various chromatographic Techniques and AKTA purification systems (AKTA purifier, AKTA Explorer; etc.) with UNICORN software, under cGMP and GLP guidelines. * Knowledge of using statistical approach-Design of Experiments (DoE) for process development (to screen chromatographic media/ conditions for optimum binding, wash, elution, and cleaning-in-place and determine adsorption isotherms). * Knowledge of the concepts of the design space, QbD (for process characterization and validation) and Risk assessment/mitigation, in biopharmaceutical development. * Extensive experience in analytical characterization of recombinant antigens using various Techniques including- HPLC, IEF, SDS-PAGE, Western blots, etc. * Experienced in Technology transfer of fermentation and purification processes to pilot scale cGMP manufacturing facilities. * Experienced working in a cGMP environment and cGMP documentation practices. * Experienced in supervising, motivating and mentoring junior staff-scientists and engineers. * Experienced in writing Standard Operating Procedures (SOPs) and Batch Production Records (BPRs). Preparation of Technical reports and contributing to CMC sections of INDs. * Experienced in developing and implementing improvements to clinical manufacturing processes. * Published the results of scientific research studies in peer reviewed journals and presented at national and international scientific meetings. * Reviewed SBIR and STIR grant proposals for NSF, USA. Reviewed grant application for National Medical Research Council, Singapore. * Evaluated Ph. D and Master level research theses. * Taught Bioinorganic, Advanced Inorganic, Bioanalytical, Analytical and Organo-metallic Chemistry courses to graduate and undergraduate students. * Taught MICR210 Lecture to Graduate (IBS) Students, GWU. Lecture Topic: Bacteria as Expression Vectors.

Yisheng US Biopharma, Inc.
Gaithersburg, MD
Mar 2010 to Jul 2011
Director, Downstream Process Development
Human Hookworm vaccine Initiative (HHVI), Sabin Vaccine Institute (SVI), GWU
Washington, DC
Nov 2002 to Feb 2010
Director Process Development & Technology Transfer
EntreMed Inc
Rockville, MD
Apr 2002 to Aug 2002
Research Scientist
University of Maryland Baltimore County (UMBC)
Baltimore, MD
Aug 1997 to Feb 2001
Assistant Research Professor

University of Maryland Baltimore County(UMBC)
Baltimore, MD
Jan 1996 to Jan 1997
Postdoctoral Research in the areas of protein engineering, expression, purification and chracterization: Selected affinity ligands from a phage sisplayed antibody library, that have applications in purification of homologus proteins like Protein C,Factor IX and Factor X. Managed Protein Engineering Laboratory.
University of Pittsburgh
Pittsburgh, PA
Jan 1994 to Jan 1996
Postdoctoral Research in ihe areas of protein engineering, expression, purification and charcterization: Identified specific peptide ligands for immobilized metal ions Cu(II) and Ni(II) using peptide library displayed on bacteriophage that have applications in host cell contaminant free protein purification by IMAC.
University of Arizona
Tucson, AZ
Jan 1994 to Jan 1994
Postdoctoral Research in the areas of protein purification and charcterization: Purified proteins involved in the detoxification of Arsenic, using Immobilized Metal ion Affinity, Arsenical Affinity and Covalent chromatographic and other bioanalytical techniques.
Universite de Technologie de Compigne
Compigne (60)
Jan 1990 to Jan 1990
Postdoctoral Research in ine area of protein purification: Studied the Immobilized Metal ion Affinity Chromatography of Lectins.
Osmania University
Hyderabad, Andhra Pradesh
Jan 1976 to Jan 1983
Ph.D in Chemistry (Bioinorganic)
Osmania University
Hyderabad, Andhra Pradesh
Jan 1976 to Jan 1978
M.Sc in Chemistry (Bioinorganic)
Osmania University
Hyderabad, Andhra Pradesh
Jan 1973 to Jan 1976
B.Sc in Biology & Chemistry

*Extensive experience in the development and optimization of scalable and robust fermentation processes (using Bioflo 3000 and fermentors with Biocommand software, micro, ultra and crossflow filtration systems) under GLP and cGMP guidelines. *Highly Experienced in the development and optimization of scalable and robust purification processes of recombinant antigens using various chromatographic Techniques and AKTA purification systems (AKTA purifier, AKTA Explorer; etc.) with UNICORN software. *Highly Experienced in Technology transfer of fermentation and purification processes to pilot scale cGMP manufacturing facilities. *Experienced working in a cGMP environment and cGMP documentation practices. *Experienced in writing Standard Operating Procedures (SOPs) and Batch Production Records (BPRs). *Experienced in Preparation of Technical reports and contributing to CMC sections of INDs. *Extensive experience in analytical characterization of recombinant antigens using various Techniques including- HPLC, IEF, SDS-PAGE Western blots, etc. *Experienced in developing and implementing improvements to clinical manufacturing processes. *Knowledge of using statistical approach-Design of Experiments (DoE) for process development (to screen chromatographic media/conditions for optimum binding, wash, elution, and cleaning-in-place and determine adsorption isotherms). *Experienced in supervising, motivating and mentoring junior staff- scientists and engineers.