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Fred Christopher Zusi

from Hamden, CT
Age ~74

Fred Zusi Phones & Addresses

  • 20 Nolan Rd, Hamden, CT 06514 (203) 287-0725
  • Lima, NY
  • Three Mile Bay, NY
  • Webster, NY
  • Tonawanda, NY
  • Newton Falls, OH
  • Jefferson, NY

Publications

Us Patents

Trifluoromethyl Ketone Analogs As Selective Cpla2 Inhibitors

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US Patent:
6350892, Feb 26, 2002
Filed:
Feb 18, 2000
Appl. No.:
09/507782
Inventors:
Jacques Banville - St-Hubert, CA
Yonghua Gai - Killingworth CT
Graham Johnson - Madison CT
Fred Christopher Zusi - Hamden CT
James R. Burke - Upper Holland PA
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07F 704
US Classification:
556436, 514 63, 514648, 514676, 514709, 556440, 564316, 568 31, 568 43
Abstract:
Selective inhibitors of the cPLA enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula where (Râ), p, D, Y, Z, R , R and A are as defined in the specification.

Compounds Having Retinoid-Like Activity

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US Patent:
6825233, Nov 30, 2004
Filed:
Feb 13, 2002
Appl. No.:
10/075845
Inventors:
Anna Ericsson - Shrewsbury MA
Anne Marinier - Kirkland, CA
Fred C. Zusi - Hamden CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31235
US Classification:
514544, 514569, 560 56, 562466
Abstract:
There are provided compounds represented by the formula I or a nontoxic pharmaceutically acceptable salt, physiologically hydrolyzable ester or solvate thereof, wherein the various substituents are as defined. Also included are methods for preventing and/or treating tumors, arthritis, and non-malignant skin disorders comprising administering a compound of formula I to a mammal. Further provided are pharmaceutical formulations comprising a compound of formula I in admixture with one or more pharmaceutically acceptable excipients.

Methods Of Treating Inflammatory And Immune Diseases Using Inhibitors Of Iκb Kinase (Ikk)

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US Patent:
6869956, Mar 22, 2005
Filed:
Feb 1, 2002
Appl. No.:
10/062847
Inventors:
James R. Burke - Holland PA, US
Robert M. Townsend - Boothwyn PA, US
Yuping Qiu - Windsor CT, US
Fred Christopher Zusi - Hamden CT, US
Steven G. Nadler - Boothwyn PA, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61P001/00
A61P011/06
A61P019/02
A61P037/06
C07D487/04
US Classification:
514250
Abstract:
The present invention describes methods of preventing and treating inflammatory and immune-related diseases or disorders using inhibitors of IκB kinase (IKK). Also described are IKK inhibitors effective for the prevention and treatment of inflammatory and immune-related diseases or disorders, as demonstrated in vivo. Further embodiments of the present invention relate to a specific IKK inhibitors, 4(2′-aminoethyl)amino-1,8-dimethylimidazo(1,2-a) quinoxaline and compounds of formula (I), salts thereof, and pharmaceutical compositions.

Amino-Substituted Tetracyclic Compounds Useful As Anti-Inflammatory Agents And Pharmaceutical Compositions Comprising Same

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US Patent:
6960585, Nov 1, 2005
Filed:
Sep 27, 2001
Appl. No.:
09/965977
Inventors:
Francis Beaulieu - Laprairie, CA
Carl Quellet - Boucherville, CA
Makonen Belema - New Haven CT, US
Yuping Qiu - Windsor CT, US
Xuejie Yang - Middletown CT, US
Fred C. Zusi - Hamden CT, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K031/519
A61K031/4985
C07D487/04
US Classification:
514248, 514257, 514285, 514287, 544247, 544343, 546 64
Abstract:
Compounds of formula (I), or pharmaceutically-acceptable salts thereof, are useful in treating inflammatory and immune diseases and disorders,.

Triazolopurine-Based Tricyclic Compounds And Pharmaceutical Compositions Comprising Same

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US Patent:
7071333, Jul 4, 2006
Filed:
Jul 29, 2004
Appl. No.:
10/901677
Inventors:
Donald Combs - Neptune City NJ, US
Charles M. Langevine - Brooklyn NY, US
Yuping Qiu - Glastonbury CT, US
Fred Christopher Zusi - Hamden CT, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D 487/14
A61K 31/519
A61P 11/06
A61P 19/02
US Classification:
544251, 514267
Abstract:
The present invention provides for triazolopurine-based tricyclic compounds having the formula (I),.

Imidazo-Fused Oxazolo[4,5-Β]Pyridine And Imidazo-Fused Thiazolo[4,5-Β]Pyridine Based Tricyclic Compounds And Pharmaceutical Compositions Comprising Same

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US Patent:
7176214, Feb 13, 2007
Filed:
May 18, 2004
Appl. No.:
10/848412
Inventors:
William J. Pitts - Newtown PA, US
Makonen Belema - North Haven CT, US
Patrice Gill - Chateauguay, CA
James Kempson - Princeton NJ, US
Yuping Qiu - Glastonbury CT, US
Claude A. Quesnelle - Brossard, CA
Steven H. Spergel - Warrington PA, US
Fred Christopher Zusi - Hamden CT, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31/4353
C07D 498/12
US Classification:
514293, 546 83, 544 60, 544126, 544361, 540575, 540599, 514218, 5142285, 514212, 5142328, 514253, 514254
Abstract:
The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I),.

Pyrazolopurine-Based Tricyclic Compounds And Pharmaceutical Compositions Comprising Same

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US Patent:
7329668, Feb 12, 2008
Filed:
Feb 24, 2004
Appl. No.:
10/785612
Inventors:
Yuping Qiu - Glastonbury CT, US
Makonen Belema - North Haven CT, US
Xuejie Yang - Wallingford CT, US
Fred Christopher Zusi - Hamden CT, US
William J. Pitts - Newtown PA, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A01N 43/54
A61K 31/505
C07D 239/00
C07D 471/00
C07D 487/00
C07D 491/00
US Classification:
514267, 544251
Abstract:
The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I),.

Synergist Combinations Of Retinoid Receptor Ligands And Selected Cytotoxic Agents For Treatment Of Cancer

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US Patent:
20040122080, Jun 24, 2004
Filed:
Feb 19, 2004
Appl. No.:
10/472690
Inventors:
Valerie Vivat-Hannah - Andlau, FR
Matthew Lorenzi - Philadelphia PA, US
Marco Gottardis - Princeton NJ, US
Fred Zusi - Hamden CT, US
International Classification:
A61K031/337
A61K031/19
US Classification:
514/449000, 514/568000
Abstract:
Chemotherapeutic combinations of selected cytotoxic agents and RAR/ selective agonists or RAR pan antagonists for use in treating cancer and lowering the effective cytotoxic dose of the selected cytotoxic agent are provided.
Fred Christopher Zusi from Hamden, CT, age ~74 Get Report