Fred Henrik Co

6511458, Jan 28, 2003

Jan 19, 2001

09/765777

Charles F. Milo - Union City CA
Matthew R. Selmon - Woodside CA
Richard E. Hill - Berkeley CA
Fred H. Co - Santa Clara CA
Ronald G. French - Palo Alto CA

LuMend, Inc. - Redwood City CA

A61M 5178

60416413, 604272, 600585

Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other interventional and diagnostic catheters.

6514217, Feb 4, 2003

Apr 25, 2000

09/557379

Matthew R. Selmon - Atherton CA
Charles F. Milo - San Mateo CA
Fred Co - Santa Clara CA
Mark Campello - Millbrae CA
Ronald French - Palo Alto CA
Amiel Aguilar - Palo Alto CA

LuMend, Inc. - Redwood City CA

A61B 500

600585, 604523

Methods and apparatus for crossing totally to substantially occluded blood vessels by passing a redirectable wire such as a guidewire from a relatively proximal point past the occlusion within a subintimal space formed between the intimal layer and the adventitial layer of a blood vessel wall. The wire may be advanced to a point distal to the occlusion, and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. The deflecting catheter may include a flapper valve assembly or preformed actuator wire for redirecting the guidewire. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn, and the guidewire may be available for introduction of other interventional and diagnostic catheters for performing procedures such as stenting.

6596010, Jul 22, 2003

Aug 27, 1999

09/385125

George D. Hermann - Portola Valley CA
Fred H. Co - Santa Clara CA
Douglas S. Sutton - Pacifica CA

General Surgical Innovations, Inc. - Norwalk CT

A61M 2900

606192, 606190

Balloon loaded dissection devices with elongate balloons and a pushing member are disclosed for creating a tunnel alongside an elongate vessel in the body. The devices may utilize an elongate balloon of any suitable length which may be formed of an elastic or non-elastic material. The balloon may be of double walled construction and may be provided with a central lumen which may receive a guide rod, scope or other surgical instrument. The device may have a support tube secured to the inner wall of the balloon to provide columnar support for the apparatus. In a further aspect, the support tube may have a spoon-shaped shroud attached to a distal end of the support tube. The support tube receives the guide rod, to scope or other surgical instrument and may have a stop member to translate pushing force applied to the guide rod or scope to pushing force on the apparatus. By using the guide rod or scope as a pushing member the apparatus may be advanced alongside the vessel it is desired to dissect free from attached tissue. A balloon cover which may be elastic or resilient is provided to surround the balloon and facilitate compression of the balloon after it is deflated.

6626901, Sep 30, 2003

Aug 13, 1999

09/374563

Michael R. Treat - New York NY
Fred H. Co - Santa Clara CA
George D. Hermann - Portola Valley CA
Thomas A. Howell - Palo Alto CA
Theodore R. Kucklick - Los Gatos CA
Michelle Y. Monfort - Los Gatos CA
Kenneth H. Mollenauer - Saratoga CA

The Trustees of Columbia University in the City of New York - New York NY

A61B 1808

606 29, 606 30, 606 31

An instrument and method are provided for sealing and joining or hemostatically dividing tissue, which is particularly suitable for laparoscopic and endoscopic surgery. The instrument makes use of the controlled application of a combination of heat and pressure to seal adjacent tissues, to join adjacent tissues, or to anastomose tissues, whereby tissue is heated for an optimal time and at an optimal temperature under optimal pressure to maximize tissue seal strength while minimizing collateral tissue damage. The instrument of the present invention is lightweight and therefore portable, and is particularly useful in field conditions where a source of external power may not be readily available.

6719725, Apr 13, 2004

Dec 3, 2002

10/308568

Charles F. Milo - Union City CA
Matthew R. Selmon - Woodside CA
Richard E. Hill - Berkeley CA
Fred H. Co - Santa Clara CA
Ronald G. French - Palo Alto CA

LuMend, Inc. - Redwood City CA

A61M 5178

60416401, 60416411, 600585

Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other interventional and diagnostic catheters.

6860880, Mar 1, 2005

Nov 12, 2002

10/292727

Michael R. Treat - New York NY, US
Fred H. Co - Santa Clara CA, US
George D. Hermann - Portola Valley CA, US
Thomas A. Howell - Palo Alto CA, US
Theodore R. Kucklick - Los Gatos CA, US
Michelle Y. Monfort - Los Gatos CA, US
Kenneth H. Mollenauer - Saratoga CA, US

The Trustees of Columbia University in the City of New York - New York NY

A61B018/08
A61B018/10

606 29, 606 30, 606 31, 219233, 219236, 219240

An instrument and method are provided for sealing and joining or hemostatically dividing tissue, which is particularly suitable for laparoscopic and endoscopic surgery. The instrument makes use of the controlled application of a combination of heat and pressure to seal adjacent tissues, to join adjacent tissues, or to anastomose tissues, whereby tissue is heated for an optimal time and at an optimal temperature under optimal pressure to maximize tissue seal strength while minimizing collateral tissue damage. The instrument of the present invention is lightweight and therefore portable, and is particularly useful in field conditions where a source of external power may not be readily available.

6908463, Jun 21, 2005

Apr 20, 2001

09/839988

Michael R. Treat - New York NY, US
Fred H. Co - Santa Clara CA, US
George D. Hermann - Portola Valley CA, US
Thomas A. Howell - Palo Alto CA, US
Theodore R. Kucklick - Los Gatos CA, US
Michelle Y. Monfort - Los Gatos CA, US
Kenneth H. Mollenauer - Saratoga CA, US

The Trustees of Columbia University in the City of New York - New York NY

A61B018/08
A61B018/10

606 29, 606 30, 606 31

An instrument and method are provided for sealing and joining or hemostatically dividing tissue, which is particularly suitable for laparoscopic and endoscopic surgery. The instrument makes use of the controlled application of a combination of heat and pressure to seal adjacent tissues, to join adjacent tissues, or to anastomose tissues, whereby tissue is heated for an optimal time and at an optimal temperature under optimal pressure to maximize tissue seal strength while minimizing collateral tissue damage. The instrument of the present invention is lightweight and therefore portable, and is particularly useful in field conditions where a source of external power may not be readily available.

7037317, May 2, 2006

May 30, 2003

10/448937

George D. Hermann - Portola Valley CA, US
Fred H. Co - Santa Clara CA, US
Douglas S. Sutton - Pacifica CA, US

United States Surgical Corporation - Norwalk CT

A61B 29/00

606190

Balloon loaded dissection devices and methods for using such devices are disclosed. The devices include an elongate balloon and may be provided with a central lumen. The device may have a guide tube to provide columnar support. In a further aspect, the guide tube may have a spoon-shaped shroud attached to a distal end. The guide tube receives the guide rod, scope or other surgical instrument and may have a stop member. By using the guide rod or scope as a pushing member, the device may be advanced alongside the vessel it is desired to dissect free from attached tissue. A balloon cover may be provided to surround the balloon and facilitate compression of the balloon after it is deflated. In an additional feature, the guide rod and/or tubular member are plastically bendable into a curved shape such that the balloon dissector may be adjusted into a curved shape.