Inventors:
Roy A. Jensen - Gardner KS, US
Frank J. Schoenen - Lawrence KS, US
Jeffrey Aube - Lawrence KS, US
Gerald H. Lushington - Lawrence KS, US
Assignee:
University of Kansas - Lawrence KS
International Classification:
A61K 31/5375
A61K 31/423
A61K 31/426
A61K 31/4245
A61K 31/505
A61K 31/381
A61K 31/164
A61K 31/41
A61K 31/4709
A61K 31/343
A61K 31/415
A61K 31/34
A61K 31/13
A61K 31/44
A61K 31/4035
C07D 235/04
A61K 31/4184
C12N 5/00
A61P 35/00
US Classification:
5142312, 514375, 514616, 514370, 514364, 514274, 514438, 514617, 514395, 514381, 514357, 514314, 514468, 514404, 514350, 514471, 514638, 514352, 514416, 5483047, 514394, 435325
Abstract:
A pharmaceutical composition for use in treating, inhibiting, and/or preventing breast and/or ovarian cancer can include: a molecule having a structure of one of Compounds 1-38, pharmaceutically acceptable salt thereof, or analog thereof, and a pharmaceutically acceptable carrier containing the compound. The pharmaceutically acceptable carrier can be configured for oral, systemic, transdermal, intranasal, suppository, parenteral, intramuscular, intravenous, or subcutaneous administration. The compound can be present in the composition in a therapeutically effective amount for treating, inhibiting, and/or preventing breast and/or ovarian cancer. Also, the compound can be present in a therapeutically effective amount for enhancing production of BRCA1.