Francesco S Facchini

20010007868, Jul 12, 2001

Jun 4, 1999

09/326735

FRANCESCO FACCHINI - SAN FRANCISCO CA, US

A61K031/7004
A61K033/26
A61K031/663

514/185000, 514/189000, 514/023000, 424/675000, 424/678000, 424/686000

Methods and compositions of matter are provided that enable a phased reduction of body iron stores to near a iron deficiency level, and thereafter maintain the body iron stores at that level by reducing further iron accumulation. In a first phase, a patient's body iron stores are reduced to a level of near iron deficiency by regular periodic phlebotomy or use of pharmacological agents, such as iron chelators, for example, over a period of six to twelve months. In a second phase, ingested iron absorption is controlled using an oral dose, taken at mealtimes, of any of various compounds that inhibit intestinal iron absorption, or by continuing, less frequent phlebotomy.

61470708, Nov 14, 2000

Jun 5, 1998

9/092521

Francesco Facchini - San Francisco CA

A01N 5504

514189

Methods and compositions of matter are provided that enable a phased reduction of body iron stores to near a iron deficiency level, and thereafter maintain the body iron stores at that level by reducing further iron accumulation. In a first phase, a patient's body iron stores are reduced to a level of near iron deficiency by regular periodic phlebotomy or use of pharmacological agents, such as iron chelators, for example, over a period of six to twelve months. In a second phase, ingested iron absorption is controlled using an oral dose, taken at mealtimes, of compound comprising a calcium salt and salts of phytic acid, without or without zinc, or by continuing, less frequent phlebotomy.