US Patent:
20090208944, Aug 20, 2009
Inventors:
Matthew P. Goetz - Rochester MN, US
James N. Ingle - Rochester MN, US
Richard M. Weinshilboum - Rochester MN, US
Fergus J. Couch - Rochester MN, US
Matthew M. Ames - Rochester MN, US
International Classification:
C12Q 1/68
Abstract:
This document provides methods and materials related to assessing the likely outcome for mammals (e.g., humans) with cancer (e.g., breast cancer). For example, methods and materials that involve assessing a breast cancer patient's cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) genotype to determine the likelihood of the beast cancer patient to experience breast cancer relapse or death are provided. Methods and materials that involve assessing the likelihood that a breast cancer patient being treated with tamoxifen will experience side effects such as hot flashes also are provided.
