US Patent:
20090136559, May 28, 2009
Inventors:
Kyriacos A. Athanasiou - Houston TX, US
Gwendolyn Hoben - Houston TX, US
Eugene Koay - Houston TX, US
Jerry Hu - Houston TX, US
International Classification:
A61F 2/00
C12N 5/08
A61K 35/12
US Classification:
424423, 435366, 435377, 435347, 424 937
Abstract:
Methods for inducing differentiation of human embryonic stem cells into chondrocytes for use in tissue engineering applications are provided. One example of a method is a method for inducing differentiation of human embryonic stem cells into chondrocytes comprising aggregating undifferentiated human embryonic stem cells to form embryoid bodies; and culturing the embryoid bodies in culture medium in the presence of growth factors that induce chondrogenic differentiation of the embryoid bodies.
