Inventors:
- Murfreesboro TN, US
Zachary E. TAYLOR - Nashville TN, US
Scott HANDY - Murfreesboro TN, US
Mary FARONE - Murfreesboro TN, US
Erin MCCLELLAND - Murfreesboro TN, US
Caleb SUTTON - Nashville TN, US
Anthony FARONE - Murfreesboro TN, US
Hyo PARK - Shelbyville TN, US
Danielle ARAUJO - Murfreesboro TN, US
Anthony NEWSOME - Murfreesboro TN, US
Assignee:
MIDDLE TENNESSEE STATE UNIVERSITY - Murfreesboro TN
International Classification:
C07D 307/88
A61P 33/02
A61P 31/10
C07D 405/06
C07D 403/06
C07D 409/06
C07F 17/02
Abstract:
Substituted aurones were found to have antitrypanosomal, antifungal and immunomodulatory activity. The invention provides novel aurone compounds, pharmaceutical compositions, and methods encompassing medical and veterinary applications.