Elliot R Mcveigh

6549800, Apr 15, 2003

Apr 14, 2000

09/549921

Ergin Atalar - Columbia MD
Paul A. Bottomley - Columbia MD
Henry Halperin - Baltimore MD
Elliot McVeigh - Potomac MD
Albert C. Lardo - Lutherville MD

Johns Hopkins Unversity School of Medicine - Baltimore MD

A61B 505

600423, 600407, 600410, 600415, 600417, 600424, 606130, 324301, 324244, 324256, 324257, 324260

The systems and methods of the present invention provide for MRI probes adapted for insertion into a plurality of body orifices, in order to evaluate the anatomy of proximate anatomic structures, to diagnose abnormalities thereof and to treat the diagnosed abnormalities. MRI probes are described that are suitable for use in the mediastinum, in the pancreaticohepaticobiliary system, in the tracheobronchopulmonary system, in the head and neck, in the genitourinary system, the gastrointestinal system, the vascular system, and in the evaluation, diagnosis and treatment of internal fluid collections.

6556009, Apr 29, 2003

Dec 11, 2000

09/735263

Peter Kellman - Bethesda MD
Elliot McVeigh - Phoenix MD

The United States of America as represented by the Department of Health and Human Services - Washington DC

G01V 300

324309, 324307, 324318, 324322, 382260

An apparatus and method for accelerating magnetic resonance imaging by decreasing the number of sequential phase encodes (undersampling). Image reconstruction of undersampled k-space data can cause ghost artifacts to be produced in the resulting sequence of images. A combination of temporal and spatial filters are used to substantially suppress the ghost artifacts. Additionally, the spatial filter receives spatial filter coefficients used in the filtering process. The spatial filter coefficients are adaptively or dynamically generated so that the coefficients are provided to the spatial filter while generating the sequence of images.

6701176, Mar 2, 2004

Oct 29, 1999

09/428990

Henry R. Halperin - Baltimore MD
Ronald D. Berger - Baltimore MD
Ergin Atalar - Columbia MD
Elliot R. McVeigh - Potomac MD
Albert Lardo - Baldwin MD
Hugh Calkins - Balt MD
Joao Lima - Timonium MD

Johns Hopkins University School of Medicine - Baltimore MD

A61B 5055

600411, 600422, 324307

A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention is particularly applicable to catheter ablation, e. g. , ablation of atrial fibrillation. In embodiments which are useful for catheter ablation, the combined electrophysiology and imaging antenna catheter may further include an ablation tip, and such embodiment may be used as an intracardiac device to both deliver energy to selected areas of tissue and visualize the resulting ablation lesions, thereby greatly simplifying production of continuous linear lesions. The invention further includes embodiments useful for guiding electrophysiologic diagnostic and therapeutic procedures other than ablation.

6771067, Aug 3, 2004

Apr 3, 2001

09/825617

Peter Kellman - Bethesda MD
Elliot McVeigh - Phoenix MD

The United States of America as represented by the Department of Health and Human Services - Washington DC

G01V 300

324307, 324309

A ghost artifact cancellation technique is disclosed. Phased array combining is used to cancel ghosts caused by a variety of distortion mechanisms, including space-variant distortions, such as local flow or off-resonance. The technique uses a constrained optimization that optimizes signal-to-noise ratio (SNR) subject to the constraint of nulling ghost artifacts at known locations. In one aspect multi-coil, k-space data is passed through a converter to convert the k-space data to image domain. After the conversion, the images contain ghost artifacts. The images are then passed through one or more phased array combiners. Each phased array combiner separates the superimposed ghosts to produce an image without ghosts. These images may then be aligned by means of shifting and combined by a variety of means to improve the final image quality. In another aspect, the phase encode order is varied in time to produce ghosts with time varying phase.

7154268, Dec 26, 2006

Oct 17, 2002

10/492897

Peter Kellman - Bethesda MD, US
Elliot McVeigh - Phoenix MD, US

The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC

G01V 3/00

324309, 324318

An MRI imaging system includes at least one processor and a plurality of coils to acquire a plurality of k-space samples of a target to image. The system includes a machine-readable media comprising instructions which, when executed by the processor, result in determining a plurality of different regularization matrices for a plurality of different regions of an image of the target. The regularization matrices are applied in the determination of a plurality of unmixing matrices for the regions. The unmixing matrices are applied to produce the image without ghost artifacts, from a plurality of MRI images produced from the plurality of k-space samples and each comprising ghost artifacts.

7155271, Dec 26, 2006

Apr 28, 2003

10/424093

Henry R. Halperin - Baltimore MD, US
Ronald D. Berger - Baltimore MD, US
Ergin Atalar - Columbia MD, US
Elliot R. McVeigh - Potomac MD, US
Albert Lardo - Baldwin MD, US
Hugh Calkins - Baltimore MD, US
Joao Lima - Timonium MD, US

Johns Hopkins University School of Medicine - Baltimore MD

A61B 5/055

600411, 324307, 324309, 324318, 600421

A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention is particularly applicable to catheter ablation, e. g. , ablation of atrial fibrillation. In embodiments which are useful for catheter ablation, the combined electrophysiology and imaging antenna catheter may further include an ablation tip, and such embodiment may be used as an intracardiac device to both deliver energy to selected areas of tissue and visualize the resulting ablation lesions, thereby greatly simplifying production of continuous linear lesions. The invention further includes embodiments useful for guiding electrophysiologic diagnostic and therapeutic procedures other than ablation.

7253620, Aug 7, 2007

Mar 8, 2005

11/075415

John Andrew Derbyshire - Silver Spring MD, US
Daniel Alfredo Herzka - Rockville MD, US
Elliot R. McVeigh - Phoenix MD, US

United States of America, as represented by the Secretary, Department of Health and Human Services - Washington DC

G01V 3/00

324307, 324309

A method that exploits the intrinsic selectivity of steady-state free precession (SSFP) to perform spectral suppression is disclosed. Such a method avoids the need to incorporate additional spectrally selective pulse sequence elements. The scheme is based on breaking the FISP imaging sequence into short trains having, for example, 8–64 RF pulses. At the moment of echo formation (i. e. , TE=TR/2) after the last full RF pulse of the train, water signal is z-stored. Residual transverse magnetization, which include isochromats phase-opposed to the on-resonance water, is gradient crushed and RF spoiled. The stored magnetization is subsequently re-excited with little disturbance to the on-resonance steady-state water signal. The additional time required to perform the steady-state interruption is typically as little as a single TR, minimally affecting the efficiency of the imaging process. The sequence can be employed repetitively, greatly reducing the amplitude of fat signals throughout a real-time or cine imaging process.

7285954, Oct 23, 2007

Sep 14, 2005

11/227406

Reza Nezafat - Newton MA, US
Richard B. Thompson - Edmonton, CA
Elliot R. McVeigh - Phoenix MD, US

The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC

G01V 3/00

324309, 324307

Phase contrast magnetic resonance images are produced using interleaved spiral k-space scanning with a bipolar phase contrast gradient. Spiral scanning is configured so that acquisition impulse response defines a central alias free portion in a partial field of view, and signal acquisition is arranged so that moving spins are contained with this central alias free portion. First and second signals are acquired with alternate phase encodings, and a complex difference of the acquired signals is obtained. The complex difference is substantially free of aliasing artifacts within the central portion.