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Elinor Dehan Phones & Addresses

  • Albany, CA
  • Chestnut Hill, MA
  • Brookline, MA
  • New York, NY
  • 142 Middlesex Rd #1, Chestnut Hill, MA 02467

Work

Position: Retired

Education

Degree: High school graduate or higher

Publications

Us Patents

Beta -Trcp1, Beta -Trcp2 And Rsk1 Or Rsk2 Inhibitors And Methods For Sensitizing Target Cells To Apoptosis

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US Patent:
20090318535, Dec 24, 2009
Filed:
Jun 4, 2009
Appl. No.:
12/478003
Inventors:
Michele Pagano - New York NY, US
Elinor Dehan - New York NY, US
Assignee:
New York University - New York NY
International Classification:
A61K 48/00
C12N 5/00
C12Q 1/02
C12Q 1/68
A61P 35/00
C07H 21/02
US Classification:
514 44 A, 435375, 435 29, 435 6, 536 231
Abstract:
The invention relates to modulating BimEL levels (Bcl-2-Interacting Mediator of cell death, Extra Long isoform) to sensitize cancer cells to cell death or apoptosis. In certain embodiments, the invention relates to increasing BimEL levels. In certain embodiments, the invention relates to inhibitors of at least one of β-TrCP1/2 or RSK1/2 proteins that sensitize tumor cells to chemotherapy-induced death or apoptosis. Additionally, the invention relates to cancer therapies, diagnostics, and methods for identifying novel drugs or drug candidates for increasing BimEL levels.
Elinor Dehan from Albany, CA, age ~51 Get Report