Search

Elena Govorkova Phones & Addresses

  • 7591 Dexter Hills Dr, Cordova, TN 38018
  • 1046 Oakmont Pl, Memphis, TN 38107 (901) 278-8555
  • 1039 Cabana Cir, Memphis, TN 38107 (901) 278-3657
  • 1045 Cabana Cir, Memphis, TN 38107
  • Shiloh, TN
  • 7591 Dexter Hills Dr, Cordova, TN 38016 (901) 737-4547

Work

Company: St. jude children's research hospital Position: Laboratory director

Education

Degree: High school graduate or higher

Industries

Hospital & Health Care

Resumes

Resumes

Elena Govorkova Photo 1

Laboratory Director

View page
Location:
Memphis, TN
Industry:
Hospital & Health Care
Work:
St. Jude Children's Research Hospital
Laboratory Director

Publications

Us Patents

Modified Influenza Virus For Monitoring And Improving Vaccine Efficiency

View page
US Patent:
8293247, Oct 23, 2012
Filed:
Dec 9, 2010
Appl. No.:
12/964491
Inventors:
Erich Hoffmann - Galveston TX, US
Aleksandr S. Lipatov - Atlanta GA, US
Richard J. Webby - Memphis TN, US
Elena A. Govorkova - Cordova TN, US
Robert G. Webster - Memphis TN, US
Assignee:
St. Jude Children's Research Hospital - Memphis TN
International Classification:
A61K 39/145
US Classification:
4242061, 4242051, 4241991, 4241881, 4241851, 4242091, 424 936, 435 5, 435 691, 530350
Abstract:
The immunogenicity of the influenza virus hemagglutinin (HA) molecule may be increased by substitutions of amino acids in the HA sequence. The substitution of specific HA residues, such as asparagine at position 223 of H5 HA, increase the sensitivity of the hemagglutinin inhibition (HI) assay by altering receptor specificity and/or antibody-antigen binding. HA molecules containing such substitutions will be useful in the development of diagnostic reference viruses and improved influenza vaccines.

Modified Influenza Virus For Monitoring And Improving Vaccine Efficiency

View page
US Patent:
8574592, Nov 5, 2013
Filed:
Sep 13, 2012
Appl. No.:
13/614835
Inventors:
Erich Hoffmann - Galveston TX, US
Aleksandr S. Lipatov - Atlanta GA, US
Richard J. Webby - Memphis TN, US
Elena A. Govorkova - Cordova TN, US
Robert G. Webster - Memphis TN, US
Assignee:
St. Jude Children's Research Hospital - Memphis TN
International Classification:
A61K 39/145
A61K 39/12
A61K 39/00
A01N 63/00
C12Q 1/70
C12P 21/06
C07K 14/00
US Classification:
4242061, 4242051, 4241991, 4241861, 4241851, 4242091, 424 936, 435 5, 435 691, 530350
Abstract:
The immunogenicity of the influenza virus hemagglutinin (HA) molecule may be increased by substitutions of amino acids in the HA sequence. The substitution of specific HA residues, such as asparagine at position 223 of H5 HA, increase the sensitivity of the hemagglutinin inhibition (HI) assay by altering receptor specificity and/or antibody-antigen binding. HA molecules containing such substitutions will be useful in the development of diagnostic reference viruses and improved influenza vaccines.

Modified Influenza Virus For Monitoring And Improving Vaccine Efficiency

View page
US Patent:
20070031453, Feb 8, 2007
Filed:
Jul 27, 2006
Appl. No.:
11/460584
Inventors:
Erich Hoffmann - Memphis TN, US
Aleksandr Lipatov - Bartlett TN, US
Richard Webby - Memphis TN, US
Elena Govorkova - Cordova TN, US
Robert Webster - Memphis TN, US
International Classification:
A61K 39/145
C12Q 1/70
C07H 21/04
C12N 7/00
C07K 14/11
US Classification:
424209100, 435005000, 435069300, 435456000, 435325000, 530350000, 536023720, 435235100
Abstract:
The immunogenicity of the influenza virus hemagglutinin (HA) molecule may be increased by substitutions of amino acids in the HA sequence. The substitution of specific HA residues, such as asparagine at position 223 of H5 HA, increase the sensitivity of the hemagglutinin inhibition (HI) assay by altering receptor specificity and/or antibody-antigen binding. HA molecules containing such substitutions will be useful in the development of diagnostic reference viruses and improved influenza vaccines.

Modified Influenza Virus For Monitoring And Improving Vaccine Efficiency

View page
US Patent:
20140030702, Jan 30, 2014
Filed:
Oct 3, 2013
Appl. No.:
14/045097
Inventors:
Aleksandr S. Lipatov - Atlanta GA, US
Richard J. Webby - Memphis TN, US
Elena A. Govorkova - Cordova TN, US
Robert G. Webster - Memphis TN, US
Assignee:
St. Jude Children's Research Hospital - Memphis TN
International Classification:
C12Q 1/02
C07K 14/005
US Classification:
435 5, 536 2372, 530396, 4352351
Abstract:
The immunogenicity of the influenza virus hemagglutinin (HA) molecule may be increased by substitutions of amino acids in the HA sequence. The substitution of specific HA residues, such as asparagine at position 223 of H5 HA, increase the sensitivity of the hemagglutinin inhibition (HI) assay by altering receptor specificity and/or antibody-antigen binding. HA molecules containing such substitutions will be useful in the development of diagnostic reference viruses and improved influenza vaccines.
Elena A Govorkova from Cordova, TN, age ~69 Get Report