US Patent:
20030054042, Mar 20, 2003
Inventors:
Elaine Liversidge - West Chester PA, US
Linden Wei - Exton PA, US
International Classification:
A61K009/14
Abstract:
Methods for stabilizing chemical compounds, particularly pharmaceutical agents, using nanoparticulate compositions are described. The nanoparticulate compositions comprise a chemical compound, such as a pharmaceutical agent, and at least one surface stabilizer. The component chemical compound exhibits chemical stability, even following prolonged storage, repeated freezing-thawing cycles, exposure to elevated temperatures, or exposure to non-physiological pH conditions.