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Edward V Quadros

from Brooklyn, NY
Age ~77

Edward Quadros Phones & Addresses

  • 232 76Th St, Brooklyn, NY 11209 (718) 238-7408
  • Washington, DC

Industries

Biotechnology

Public records

Vehicle Records

Edward Quadros

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Address:
232 76 St, Brooklyn, NY 11209
Phone:
(718) 238-7408
VIN:
WDDGF8BB0BR134134
Make:
MERCEDES-BENZ
Model:
C-CLASS
Year:
2011

Resumes

Resumes

Edward Quadros Photo 1

Edward Quadros

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Location:
Greater New York City Area
Industry:
Biotechnology

Publications

Us Patents

Method For Detecting The Affinity Of Folate Receptor Auto Antibodies

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US Patent:
7846672, Dec 7, 2010
Filed:
Nov 7, 2003
Appl. No.:
10/534303
Inventors:
Sheldon P. Rothenberg - New York NY, US
Maria da Costa - New York NY, US
Jeffrey Sequeira - Brooklyn NY, US
Edward V. Quadros - Brooklyn NY, US
International Classification:
G01N 33/53
G01N 33/567
G01N 33/48
US Classification:
435 71, 435 72, 435 77, 435 4051
Abstract:
The present invention identifies autoantibodies to folate receptors. Methods to identify these autoantibodies to the human folate receptors are also provided. The present invention also contemplates diagnostic methods and test kits to be used in a clinical setting for identifying a subject at risk of folate-sensitive abnormalities or disorders as observed in neural tube defect complicated pregnancies. In addition, infertility, spontaneous abortion, male sterility, unsuccessful in vitro fertilization, neurologic disorders and impaired folate absorption may also be associated with these autoantibodies to folate receptors.

Transcobalamin Receptor Polypeptides, Nucleic Acids, And Modulators Thereof, And Related Methods Of Use In Modulating Cell Growth And Treating Cancer And Cobalamin Deficiency

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US Patent:
8524454, Sep 3, 2013
Filed:
Apr 5, 2007
Appl. No.:
12/296254
Inventors:
Edward V. Quadros - Brooklyn NY, US
Jeffrey M. Sequeira - Brooklyn NY, US
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
G01N 33/53
G01N 33/567
US Classification:
435 71, 435 72, 435 721, 436505
Abstract:
The present invention provides the amino acid and polynucleotide sequences of the transcobalamin receptor, as well as modulators of the transcobalamin receptor. Accordingly, the present invention provides compositions and methods for the treatment and prevention of diseases and disorders associated with cobalamin deficiency, including compositions and methods that promote cobalamin uptake. In addition, the present invention provides compositions and methods for the detection, treatment, and prevention of diseases associated with deregulated cell growth, including, e. g. , cancer and autoimmune disorders, including compositions and methods that inhibit cobalamin uptake.

Growth Blocking Agents

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US Patent:
20050169910, Aug 4, 2005
Filed:
Oct 1, 2004
Appl. No.:
10/956735
Inventors:
A. Morgan - Edmonds WA, US
Edward Quadros - Brooklyn NY, US
Sheldon Rothenberg - New York NY, US
Assignee:
Kyto Biopharma, Inc. - Palm Beach Gardens FL
State University of New York - Brooklyn NY
International Classification:
A61K039/395
C07K016/18
US Classification:
424130100, 530388100
Abstract:
There is disclosed anti-receptor and growth blocking agents to the vitamin B/transcobalamin II receptor and binding sites. The anti-receptor and growth blocking agents antagonize or modulate the vitamin B/transcobalamin II receptor or binding sites, causing cellular depletion of vitamin B, thus inhibiting cell division or causing apoptosis. Anti-receptor and growth blocking agents of the present invention include proteins (such as antibodies and antibody derivatives), peptides and small organic molecules. In a preferred embodiment, the anti-receptor agent is an antibody to the vitamin B/transcobalamin II receptor.

Antibodies To The B12-Transcobalamin Receptor

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US Patent:
20130164309, Jun 27, 2013
Filed:
Jul 20, 2012
Appl. No.:
13/554780
Inventors:
Edward V. Quadros - Brooklyn NY, US
Jeffrey M. Sequeira - Brooklyn NY, US
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
C07K 16/30
G01N 33/82
A61K 47/48
US Classification:
4241741, 5303897, 5303873, 53038822, 5303917, 5303913, 536 2353, 4241781, 4353201, 435334, 43525233, 435377, 436501, 435 721
Abstract:
The present invention provides anti-TCblR antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of cancer, tumors and other proliferative diseases and disorders.
Edward V Quadros from Brooklyn, NY, age ~77 Get Report