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Dos D Sarbassov

from Pearland, TX
Age ~56
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Also known as:
Dos Dilara Sarbassov, Bos Sarbassov, Dos A, Dos U, Sarbassov Bos
Phone and address:
12322 Evening Bay Dr, Pearland, TX 77584
(713) 436-1633
Related to:
Daniar D Sarbassov, 29Patricia T Smith, 56Jayme Soto, 40Alunda Smith, 59Demetrice Hall, 49
Connected to:
Hoss H Sarbaz, 53Teresa L Sarbeck, 63Diane R Sarber, 71Raymond J Sarbiewski, 73Janice L Sarbinski, 73Sara A Sarbinski, 33Gary A Sarbo, 76Linda D Sarbo, 54Radu Sarbu, 70Roxana M Sarbu, 61

Dos Sarbassov Phones & Addresses

  • 12322 Evening Bay Dr, Pearland, TX 77584 (713) 436-1633
  • 66 Stoney Hill Rd, Shrewsbury, MA 01545
  • 143 Gerry Rd, Chestnut Hill, MA 02467
  • 73 Gerry Rd, Chestnut Hill, MA 02467
  • 2420 Riverfront Dr, Little Rock, AR 72202
  • Port Jefferson Station, NY
  • New York, NY
  • Cambridge, MA
  • 12322 Evening Bay Dr, Pearland, TX 77584

Resumes

Resumes

Dos Sarbassov Photo 1

Dos Sarbassov

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Dos Sarbassov Photo 2

Assistant Professor At University Of Texas M.d. Anderson Cancer Centerr

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Location:
Houston, Texas Area
Industry:
Pharmaceuticals

Publications

Us Patents

Phosphorylation And Regulation Of Akt/Pkb By The Rictor-Mtor Complex

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US Patent:
7906308, Mar 15, 2011
Filed:
Jan 27, 2006
Appl. No.:
11/341908
Inventors:
David M. Sabatini - Cambridge MA, US
Dos D. Sarbassov - Shrewsbury MA, US
Assignee:
Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:
C12N 9/12
C12Q 1/00
C12P 21/06
C12N 15/09
C12N 9/00
A61K 38/43
A61K 39/00
A23J 1/00
US Classification:
435194, 435 4, 435 691, 435 692, 435183, 424 941, 4242771, 530412
Abstract:
In certain aspects, the invention relates to methods for identifying compounds which modulate Akt activity mediated by the rictor-mTOR complex and methods for treating or preventing a disorder that is associated with aberrant Akt activity.

Mtor Kinase-Associated Proteins

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US Patent:
8258271, Sep 4, 2012
Filed:
May 17, 2006
Appl. No.:
11/436394
Inventors:
David M. Sabatini - Cambridge MA, US
Do-Hyung Kim - Minneapolis MN, US
Dos D. Sarbassov - Shrewsbury MA, US
Assignee:
Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:
C07K 14/00
US Classification:
530827
Abstract:
The invention describes isolated mTOR-associated proteins (“mTOR-APs”) as well as isolated variants and fragments thereof and the isolated nucleic acids encoding them. The invention also describes vectors and host cells containing nucleic acid encoding an mTOR-AP polypeptide and methods for producing an mTOR-AP polypeptide. Also described are methods for screening for compounds which modulate mTOR-AP activity and methods for treating or preventing a disorder that is responsive to mTOR-AP modulation.

Methods Relating To Mammalian Raptor Polypeptide

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US Patent:
8486643, Jul 16, 2013
Filed:
Oct 7, 2010
Appl. No.:
12/900289
Inventors:
David M. Sabatini - Cambridge MA, US
Do-Hyung Kim - Minneapolis MN, US
Dos Sarbassov - Pearland TX, US
Assignee:
Whitehead Institute For Biomedical Research - Cambridge MA
International Classification:
G01N 33/53
C07K 14/435
US Classification:
435 71, 435 792, 530350
Abstract:
The present invention relates to isolated raptor nucleic acid molecules of mammalian origin (e. g. , human) and complements, portions and variants thereof. Another aspect of the invention are isolated raptor polypeptides of mammalian origin and portions thereof, and antibodies or antigen binding fragments thereof that specifically bind a raptor polypeptide. The present invention also relates to constructs and host cells comprising the nucleic acid molecules described herein. In addition, the present invention relates to uses of the nucleic acid and polypeptide molecules provided herein.

Nucleic Acids Encoding A Mammalian Raptor Polypeptide And Uses Therefor

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US Patent:
20040072207, Apr 15, 2004
Filed:
May 13, 2003
Appl. No.:
10/437421
Inventors:
David Sabatini - Cambridge MA, US
Do-Hyung Kim - Brookline MA, US
Dos Sarbassov - Chestnut Hill MA, US
Assignee:
Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:
C12Q001/68
C07H021/04
C07K014/705
C07K016/28
C12P021/02
C12N005/06
US Classification:
435/006000, 435/069100, 435/320100, 435/325000, 530/350000, 530/388220, 536/023500
Abstract:
The present invention relates to isolated raptor nucleic acid molecules of mammalian origin (e.g., human) and complements, portions and variants thereof. Another aspect of the invention are isolated raptor polypeptides of mammalian origin and portions thereof, and antibodies or antigen binding fragments thereof that specifically bind a raptor polypeptide. The present invention also relates to constructs and host cells comprising the nucleic acid molecules described herein. In addition, the present invention relates to uses of the nucleic acid and polypeptide molecules provided herein.

Mtor Kinase-Associated Proteins

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US Patent:
20040253677, Dec 16, 2004
Filed:
Feb 18, 2004
Appl. No.:
10/782244
Inventors:
David Sabatini - Cambridge MA, US
Do-Hyung Kim - Cambridge MA, US
Dos Sarbassov - Shrewsbury MA, US
Assignee:
Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:
C07K014/705
C07H021/04
US Classification:
435/069100, 536/023500, 530/350000, 435/320100, 435/325000
Abstract:
The invention describes isolated mTOR-associated proteins (“mTOR-APs”) as well as isolated variants and fragments thereof and the isolated nucleic acids encoding them. The invention also describes vectors and host cells containing nucleic acid encoding an mTOR-AP polypeptide and methods for producing an mTOR-AP polypeptide. Also described are methods for screening for compounds which modulate mTOR-AP activity and methods for treating or preventing a disorder that is responsive to mTOR-AP modulation.

Nucleic Acids Encoding A Mammalian Raptor Polypeptide And Uses Therefor

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US Patent:
20080260721, Oct 23, 2008
Filed:
Apr 18, 2007
Appl. No.:
11/788024
Inventors:
David M. Sabatini - Cambridge MA, US
Do-Hyung Kim - Brookline MA, US
Dos Sarbassov - Chestnut Hill MA, US
International Classification:
A61K 39/395
C07K 14/435
C12N 15/63
C12P 21/00
C07K 16/18
C12Q 1/68
A61P 35/00
C12N 1/21
C12N 1/19
C12N 5/10
A61K 38/17
A61K 31/70
US Classification:
4241301, 536 235, 530350, 4353201, 435 691, 5303871, 435 6, 4352523, 4352542, 435348, 435325, 514 12, 514 44
Abstract:
The present invention relates to isolated raptor nucleic acid molecules of mammalian origin (e.g., human) and complements, portions and variants thereof. Another aspect of the invention are isolated raptor polypeptides of mammalian origin and portions thereof, and antibodies or antigen binding fragments thereof that specifically bind a raptor polypeptide. The present invention also relates to constructs and host cells comprising the nucleic acid molecules described herein. In addition, the present invention relates to uses of the nucleic acid and polypeptide molecules provided herein.

Phosphorylation And Regulation Of Akt/Pkb By The Rictor-Mtor Complex

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US Patent:
20100173928, Jul 8, 2010
Filed:
Jul 15, 2008
Appl. No.:
12/218629
Inventors:
David M. Sabatini - Cambridge MA, US
Dos D. Sarbassov - Shrewsbury MA, US
Michael Andreeff - Houston TX, US
Marina Konopleva - Houston TX, US
Zhihong Zeng - Houston TX, US
Francis J. Giles - San Antonio TX, US
International Classification:
A61K 31/436
C12N 5/00
C12Q 1/02
A61P 35/00
US Classification:
514291, 435375, 435 29
Abstract:
In certain aspects, the invention relates to methods for identifying compounds which modulate Akt activity mediated by the rictor-mTOR complex and methods for treating or preventing a disorder that is associated with aberrant Akt activity.

Nucleic Acids Encoding A Mammalian Raptor Polypeptide And Uses Therefor

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US Patent:
20140004532, Jan 2, 2014
Filed:
Jun 14, 2013
Appl. No.:
13/918424
Inventors:
Do-Hyung Kim - Brookline MA, US
Dos Sarbassov - Chestnut Hill MA, US
Assignee:
Whitehead Institute For Biomedical Research - Cambridge MA
International Classification:
G01N 33/50
US Classification:
435 78, 435 15, 435375, 435 29, 530350
Abstract:
The present invention relates to isolated raptor nucleic acid molecules of mammalian origin (e.g., human) and complements, portions and variants thereof. Another aspect of the invention are isolated raptor polypeptides of mammalian origin and portions thereof, and antibodies or antigen binding fragments thereof that specifically bind a raptor polypeptide. The present invention also relates to constructs and host cells comprising the nucleic acid molecules described herein. In addition, the present invention relates to uses of the nucleic acid and polypeptide molecules provided herein.
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Dos D Sarbassov from Pearland, TX, age ~56 Get Report