US Patent:
20040180844, Sep 16, 2004
Inventors:
Stephen Fesik - Gurnee IL, US
Donald Halbert - Libertyville IL, US
Randy Metzger - Gurnee IL, US
Jeffrey McDowell - Grayslake IL, US
Mark Schurdak - Antioch IL, US
Aparna Sarthy - Waukegan IL, US
International Classification:
A61K048/00
Abstract:
A method of killing cancer cells comprising inhibiting the function of a gene selected from the group consisting of CDK8, STK33, PRKCM, PRKACA, ACVR1B, CDK5R1, CDC42BPB, MPP6, and CDC42BPA; pharmaceutical compositions comprising an inhibitor of the same, and a method of detecting cellular hyperplasia.