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Derek A Pflum

from Northville, MI
Age ~53

Derek Pflum Phones & Addresses

  • 41450 Woodridge Ct, Northville Township, MI 48167 (248) 305-8141
  • Northville, MI
  • New Haven, CT
  • Livonia, MI
  • 134 School St, Waltham, MA 02451 (781) 788-9580
  • Elbert, WV
  • Pueblo, CO
  • Boulder, CO
  • Breckenridge, CO
  • Gallup, NM

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Emails

Publications

Isbn (Books And Publications)

Modern Organic Synthesis in the Laboratory: A Collection of Standard Experimental Procedures

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Author

Derek A. Pflum

ISBN #

0195187989

Modern Organic Synthesis in the Laboratory: A Collection of Standard Experimental Procedures

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Author

Derek A. Pflum

ISBN #

0195187997

Us Patents

Methods Of Preparing Didesmethylsibutramine And Other Sibutramine Derivatives

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US Patent:
6894189, May 17, 2005
Filed:
Aug 20, 2003
Appl. No.:
10/643941
Inventors:
Chris Hugh Senanayake - Shrewsbury MA, US
Zhengxu Han - Shrewsbury MA, US
Derek Pflum - Waltham MA, US
Assignee:
Sepracor Inc. - Marlborough MA
International Classification:
C07C209/62
C07C211/17
C07C251/06
US Classification:
564248, 564338, 564415
Abstract:
This invention encompasses novel methods of preparing sibutramine and sibutramine derivatives, and stereomerically pure sibutramine derivatives in particular. Examples of sibutramine derivatives include, but are not limited to, sibutramine metabolites such as desmethylsibutramine and didesmethylsibutramine. The invention further encompasses novel compounds useful in the synthesis of sibutramine derivatives.

Glycosylated Indolocarbazole Synthesis

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US Patent:
7038043, May 2, 2006
Filed:
Jan 13, 2000
Appl. No.:
09/482235
Inventors:
John L. Wood - North Haven CT, US
Brian M. Stoltz - Auburn CA, US
Hans-Jurgen Dietrich - Zurich, CH
Derek A. Pflum - Northville MI, US
Assignee:
Yale University - New Haven CT
International Classification:
C07D 273/00
US Classification:
540545
Abstract:
Indolocarbazoles are furanosylated (e. g. , ) with acetals (e. g. , ) or their open chain congeners (e. g. , ) under conditions known to promote acetal exchange or formation, such as protic or Lewis acids. Furanosylated indolocarbazoles (e. g. , ) are also prepared via ring contraction of pyranosylated indolocarbazoles (e. g. , ) under conditions know to effect oxidation and benzylic acid type rearrangements, and pyranosylated indolocarbazoles (e. g. , ) are prepared via ring expansion of the furanosylated congeners (e. g. , ).

Methods Of Preparing Sulfinamides And Sulfoxides

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US Patent:
7064214, Jun 20, 2006
Filed:
Apr 12, 2002
Appl. No.:
10/120541
Inventors:
Chris Hugh Senanayake - Shrewsbury MA, US
Zhengxu Han - Shrewsbury MA, US
Derek Pflum - Northville MI, US
Harold Scott Wilkinson - Marlborough MA, US
Assignee:
Apsinterm LLC - Wilmington DE
International Classification:
C07D 213/02
C07D 235/04
US Classification:
546339, 548122, 548206, 5483001, 5483064
Abstract:
This invention encompasses novel methods of preparing sulfinamides and sulfoxides, particularly stereomerically pure sulfinamides and sulfoxides. The invention further encompasses novel compounds from which sulfinamides and sulfoxides can be prepared.

Methods Of Preparing Sulfinamides And Sulfoxides

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US Patent:
7256297, Aug 14, 2007
Filed:
Jan 27, 2006
Appl. No.:
11/340551
Inventors:
Chris Hugh Senanayake - Shrewsbury MA, US
Zhengxu Han - Shrewsbury MA, US
Derek Pflum - Northville MI, US
Harold Scott Wilkinson - Marlborough MA, US
Assignee:
Apsinterm, LLC. - Wilmington DE
International Classification:
C07D 291/04
US Classification:
548122
Abstract:
This invention encompasses novel methods of preparing sulfinamides and sulfoxides, particularly stereomerically pure sulfinamides and sulfoxides. The invention further encompasses novel compounds from which sulfinamides and sulfoxides can be prepared.

Methods Of Preparing Didesmethylsibutramine And Other Sibutramine Derivatives

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US Patent:
20020183554, Dec 5, 2002
Filed:
Apr 12, 2002
Appl. No.:
10/120503
Inventors:
Chris Senanayake - Shrewsbury MA, US
Zhengxu Han - Shrewsbury MA, US
Derek Pflum - Northville MI, US
International Classification:
C08B037/16
C07D211/08
C07C211/26
US Classification:
564/338000, 546/192000, 548/576000, 536/046000
Abstract:
This invention encompasses novel methods of preparing sibutramine and sibutramine derivatives, and stereomerically pure sibutramine derivatives in particular. Examples of sibutramine derivatives include, but are not limited to, sibutramine metabolites such as desmethylsibutramine and didesmethylsibutramine. The invention further encompasses novel compounds useful in the synthesis of sibutramine derivatives.

Heterocyclic Substituted Piperazines For The Treatment Of Schizophrenia

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US Patent:
20040138230, Jul 15, 2004
Filed:
Sep 12, 2003
Appl. No.:
10/660908
Inventors:
Tonja Andreana - Somerville MA, US
Stephen Yong Cho - Saline MI, US
James Graham - Ann Arbor MI, US
Tracy Gregory - Parma MI, US
Harry Howard - Bristol CT, US
Brian Kornberg - Ann Arbor MI, US
Sham Nikam - Ann Arbor MI, US
Derek Pflum - Northville MI, US
International Classification:
A61K031/496
C 07D 4 3/14
US Classification:
514/253070, 544/363000, 514/314000, 546/157000
Abstract:
This invention relates to compounds of the formula 1 wherein X, Y, Z, A, R, R, R, R, R, Wand Ware defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system and other disorders.

C1-Symmetric Bisphosphine Ligands And Their Use In The Asymmetric Synthesis Of Pregabalin

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US Patent:
20050228190, Oct 13, 2005
Filed:
Mar 11, 2005
Appl. No.:
11/078228
Inventors:
Jian Bao - Chesterfield MO, US
Vladimir Beylin - Ann Arbor MI, US
Derek Greene - Canton MI, US
Garrett Hoge - Ann Arbor MI, US
William Kissel - Ypsilanti MI, US
Mark Marlatt - Grass Lake MI, US
Derek Pflum - Northville MI, US
He-Ping Wu - Edison NJ, US
International Classification:
C07C253/30
C07C229/06
US Classification:
558410000, 562401000, 562557000
Abstract:
Materials and methods for preparing (S)-(+)-3-(aminomethyl)-5-methyl-hexanoic acid and structurally related compounds via enantioselective hydrogenation of prochiral olefins are disclosed. The methods employ novel chiral catalysts, which include C-symmetric bisphosphine ligands bound to transition metals.

Methods Of Preparing Sulfinamides And Sulfoxides

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US Patent:
20070293682, Dec 20, 2007
Filed:
Jul 30, 2007
Appl. No.:
11/830166
Inventors:
Chris Senanayake - Shrewsbury MA, US
Zhengxu Han - Shrewsbury MA, US
Derek Pflum - Northville MI, US
Harold Wilkinson - Marlborough MA, US
International Classification:
C07D 401/12
C07D 235/28
C07D 291/08
US Classification:
546273700, 548122000, 548307100
Abstract:
This invention encompasses novel methods of preparing sulfinamides and sulfoxides, particularly stereomerically pure sulfinamides and sulfoxides. The invention further encompasses novel compounds from which sulfinamides and sulfoxides can be prepared.
Derek A Pflum from Northville, MI, age ~53 Get Report