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Dennis T Drayna

from Santa Rosa, CA
Age ~72
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Also known as:
Dennis Theodore Drayna, Dennis T Korda
Related to:
Timothy K Drayna, 37Katherine V Korda, 75Garrett K Drayna, 37
Connected to:
Arlene M Drayna, 60Nicholas S Drayson, 34Adam J Drayton, 40Alishia Drayton, 30Alphonzo E Drayton, 37Andrea J Drayton, 48Anthony J Drayton, 37Ben Drayton, 115Brandy W Drayton, 39Brittany N Drayton, 34

Dennis Drayna Phones & Addresses

  • Santa Rosa, CA
  • Polebridge, MT
  • Oakland City, IN
  • 10600 Cloverbrooke Dr, Potomac, MD 20854 (301) 251-4406
  • Rockville, MD
  • Tennyson, IN
  • San Mateo, CA
  • Bethesda, MD
  • 10600 Cloverbrooke Dr, Potomac, MD 20854

Work

Position: Executive, Administrative, and Managerial Occupations

Education

Degree: Associate degree or higher

Emails

d***[email protected]

Publications

Wikipedia References

Dennis Drayna Photo 2

Dennis Drayna

Us Patents

Phenylthiocarbamide (Ptc) Taste Receptor

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US Patent:
7314725, Jan 1, 2008
Filed:
Jul 19, 2002
Appl. No.:
10/484525
Inventors:
Dennis Drayna - Potomac MD, US
Mark Leppert - Salt Lake City UT, US
Assignee:
The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC
International Classification:
C07K 14/705
C12N 15/12
G01N 33/566
US Classification:
435 721, 435 691, 435 697, 4352523, 4353201, 530350, 536 234, 536 235
Abstract:
The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.

Variants Of Human Taste Receptor Genes

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US Patent:
7579453, Aug 25, 2009
Filed:
Jun 18, 2004
Appl. No.:
10/561487
Inventors:
Dennis Drayna - Potomac MD, US
Assignee:
The United States of America as represented by the Secretary of the Dapartment of Health and Human Services - Washington DC
International Classification:
C07H 21/04
C12N 15/63
C12N 15/85
C12Q 1/68
US Classification:
536 2431, 536 231, 536 235, 4353201, 435325, 435 6, 435810
Abstract:
Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.

Phenylthiocarbamide (Ptc) Taste Receptor

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US Patent:
7666601, Feb 23, 2010
Filed:
Oct 11, 2007
Appl. No.:
11/871131
Inventors:
Dennis Drayna - Potomac MD, US
Mark Leppert - Salt Lake City UT, US
Assignee:
The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC
The University of Utah Research Foundation - Salt Lake City UT
International Classification:
C12Q 1/68
G01N 33/53
G01N 33/48
C07K 14/705
US Classification:
435 6, 435 71, 436 63
Abstract:
The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.

Phenylthiocarbamide (Ptc) Taste Receptor

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US Patent:
8148082, Apr 3, 2012
Filed:
Jan 20, 2010
Appl. No.:
12/690286
Inventors:
Dennis Drayna - Potomac MD, US
Mark Leppert - Salt Lake City UT, US
Assignee:
The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC
The University of Utah Research Foundation - Salt Lake City UT
International Classification:
C12Q 1/68
US Classification:
435 617, 435 61, 435 611
Abstract:
The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.

Variants Of Human Taste Receptor Genes

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US Patent:
8309701, Nov 13, 2012
Filed:
Aug 3, 2009
Appl. No.:
12/534505
Inventors:
Dennis Drayna - Potomac MD, US
Assignee:
The United States of America as represented by the Secrectary of the Department of Health and Human Services - Washington DC
International Classification:
C07H 21/04
C12N 15/63
C12N 15/85
C12Q 1/68
US Classification:
536 2431, 536 231, 536 235, 4353201, 435325, 435 61
Abstract:
Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.

Diagnostic And Therapeutic Uses Of Gnptab, Gnptg, And Nagpa In Stuttering

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US Patent:
8530167, Sep 10, 2013
Filed:
Feb 8, 2010
Appl. No.:
13/148340
Inventors:
Dennis T. Drayna - Potomac MD, US
Changsoo Paul Kang - Gaithersburg MD, US
Sheikh Riazuddin - Lahore, PK
Assignee:
The United States of America, as represented by the Secretary, Department of Health and Human Services - Washington DC
Centre of Excellence in Molecular Biology Together With All Allied Components, University of Punjab - Lahore
International Classification:
C12Q 1/68
C07H 21/04
US Classification:
435 613, 435 61, 536 232
Abstract:
The allelic variants or mutations in three genes: GNPTAB, GNPTG and NAGPA, that correlate with stuttering in humans, as well as the encoded mutated polypeptides and related vectors, host cells, antibodies, antibody-producing cell lines and methods of diagnosing, prognosticating and treating stuttering are provided.

Human Sweet And Umami Taste Receptor Variants

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US Patent:
20080287310, Nov 20, 2008
Filed:
Apr 13, 2006
Appl. No.:
11/911517
Inventors:
Dennis T. Drayna - Potomac MD, US
Un-Kyung Kim - Daegu, KR
International Classification:
C40B 30/04
C12N 15/11
C07K 14/00
C12N 15/00
C12N 5/06
G01N 33/00
G01N 33/566
C40B 40/08
US Classification:
506 9, 536 235, 530350, 4353201, 435369, 435358, 436 94, 436 86, 436501, 506 17
Abstract:
Identified herein are different forms of sweet and umami receptor encoding sequences that occur in different human populations. In particular, there are provided several single nucleotide polymorphisms (SNPs) that occur within the exons/coding sequence (and are therefore coding SNPs, cSNPs) of one of the three T1R genes. Some SNPs cause amino acid substitutions, while others introduce a chain termination codon, rendering a truncated product. Differences in these genes are believed to affect the sense of taste of individuals, such that individuals with different SNPs (or different haplotypes) are believed to perceive the taste of sweet or umami (e.g., glutamate) substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define groups and populations who perceive tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level.
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Dennis T Drayna from Santa Rosa, CA, age ~72 Get Report