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Denis Martin Sobieray

from Kalamazoo, MI
Age ~66
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Also known as:
Denis M Sobieray, Dennis M Sobieray
Phone and address:
5144 Shepherds Glen Rd, Kalamazoo, MI 49009
(269) 372-0827
Related to:
Brittany R Mccabe, 33Thomas John Mccabe, 34Aaron Sobieray, 35Claire M Sobieray, 31Ethan Sobieray, 33Joel Sobieray, 30
Connected to:
Henryk K Sobierajski, 76Marcin Sobieray, 55Michael F Sobieraj, 43Aleksandra C Sobieska, 32Ashley M Sobieski, 34Barbara K Sobieski, 81Christopher E Sobiesiak, 45Edward R Sobieski, 82Jacek J Sobieski, 86Jamie L Sobieski, 32

Denis Sobieray Phones & Addresses

  • 5144 Shepherds Glen Rd, Kalamazoo, MI 49009 (269) 372-0827
  • 5380 Telluride Rd, Kalamazoo, MI 49009 (269) 544-2818
  • 9657 Fawn Run, Brighton, MI 48114 (810) 225-3117
  • Holland, MI
  • Fort Collins, CO

Work

Company: Pfizer Position: Project manager

Skills

Organic Synthesis • Drug Discovery • Medicinal Chemistry • Adme • Hplc • Lc Ms • Organic Chemistry • Pharmaceutical Industry • Lead Change • Drug Design • Drug Development • Glp • Nmr • Purification • Parallel Synthesis • Analytical Chemistry • Gmp • Chemistry • Chromatography • Sop • Pharmaceutical Research • Technology Transfer • Mass Spectrometry

Industries

Pharmaceuticals

Resumes

Resumes

Denis Sobieray Photo 1

Denis Sobieray

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Location:
Kalamazoo, MI
Industry:
Pharmaceuticals
Work:
Pfizer
Project Manager
Skills:
Organic Synthesis
Drug Discovery
Medicinal Chemistry
Adme
Hplc
Lc Ms
Organic Chemistry
Pharmaceutical Industry
Lead Change
Drug Design
Drug Development
Glp
Nmr
Purification
Parallel Synthesis
Analytical Chemistry
Gmp
Chemistry
Chromatography
Sop
Pharmaceutical Research
Technology Transfer
Mass Spectrometry

Publications

Us Patents

Gaba And L-Glutamic Acid Analogs For Antiseizure Treatment

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US Patent:
6342529, Jan 29, 2002
Filed:
Feb 4, 1999
Appl. No.:
09/243946
Inventors:
Richard B. Silverman - Morton Grove IL
Ryszard Andruszkiewicz - Sopot, PL
Denis Martin Sobieray - Holland MI
Lloyd Charles Franklin - Hamilton MI
Mark Alan Schwindt - Holland MI
Assignee:
Northwestern University - Evanston IL
Pfizer, Inc. - Ann Arbor MI
International Classification:
A61K 31195
US Classification:
514561
Abstract:
A compound of the formula wherein R is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R is hydrogen or methyl; and R is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.

Gaba And L-Glutamic Acid Analogs For Antiseizure Treatment

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US Patent:
6359169, Mar 19, 2002
Filed:
Oct 16, 1996
Appl. No.:
08/732065
Inventors:
Richard B. Silverman - Morton Grove IL
Ryszard Andruszkiewicz - Sopot, PL
Denis Martin Sobieray - Holland MI
Lloyd Charles Franklin - Hamilton MI
Mark Alan Schwindt - Holland MI
Assignee:
Northwestern University - Evanston IL
Warner-Lambert Company - Ann Arbor MI
International Classification:
C07C 6934
US Classification:
560190
Abstract:
A compound of the formula wherein R is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R is hydrogen or methyl; and R is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.

Methods Of Making Dihydropyrone Hiv Protease Inhibitors

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US Patent:
6380400, Apr 30, 2002
Filed:
Oct 31, 2000
Appl. No.:
09/674381
Inventors:
Victor Fedij - Holland MI, 49424
Christopher Andrew Gajda - Ann Arbor MI, 48104
Brian Keith Huckabee - Holland MI, 49424
Brian Stuart Moon - Holland MI, 49424
Kenneth Thomas Porter - Holland MI, 49424
Denis Martin Sobieray - Holland MI, 48424
Timothy Lee Stuk - Holland MI, 49424
Bradley Dean Tait - Canton MI, 48187
James Norton Wemple - Holland MI, 49424
International Classification:
C07D30932
US Classification:
549292, 558234, 558241, 560308
Abstract:
The present invention relates to methods of making dihydropyrone HIV inhibitors.

Gaba And L-Glutamic Acid Analogs For Antiseizure Treatment

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US Patent:
6414024, Jul 2, 2002
Filed:
Feb 4, 1999
Appl. No.:
09/244700
Inventors:
Richard B. Silverman - Morton Grove IL
Ryszard Andruszkiewicz - Sopot, PL
Denis Martin Sobieray - Holland MI
Lloyd Charles Franklin - Hamilton MI
Mark Alan Schwindt - Holland MI
Assignee:
Northwestern University - Evanston IL
Warner-Lambert Company - Ann Arbor MI
International Classification:
A61K 31195
US Classification:
514561, 514567, 514568
Abstract:
A compound of the formula wherein R is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R is hydrogen or methyl; and R is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.

Gaba And L-Glutamic Acid Analogs For Antiseizure Treatment

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US Patent:
6525096, Feb 25, 2003
Filed:
Feb 4, 1999
Appl. No.:
09/244313
Inventors:
Richard B. Silverman - Morton Grove IL
Ryszard Andruszkiewicz - Sopot, PL
Denis Martin Sobieray - Holland MI
Lloyd Charles Franklin - Hamilton MI
Mark Alan Schwindt - Holland MI
Assignee:
Northwestern University - Evanston IL
Warner-Lambert Company - Ann Arbor MI
International Classification:
A61K 31195
US Classification:
514561
Abstract:
A compound of the formula wherein R is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R is hydrogen or methyl; and R is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.

Method Of Making (S)-3-(Aminomethyl) -5- Methylhexanoic Acid

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US Patent:
20010016665, Aug 23, 2001
Filed:
Oct 5, 1999
Appl. No.:
09/412258
Inventors:
TODD MICHEL GROTE - HOLLAND MI, US
BRIAN KEITH HUCKABEE - HOLLAND MI, US
THOMAS MULHERN - HUDSONVILLE MI, US
DENIS MARTIN SOBIERAY - HOLLAND MI, US
ROBERT DANIEL TITUS - INDIANAPOLIS IN, US
International Classification:
C07C255/00
US Classification:
558/441000, 558/443000
Abstract:
A method of making ()-3-(aminomethyl)-5-methylhexanoic acid that comprises condensing isovaleraldehyde with to form primarily reacting the with a cyanide source to form decarboxylating the to form hydrolyzing the with an alkali or alkaline earth metal hydroxide to form an alkali or alkaline earth metal carboxylate salt; and hydrogenating the alkali or alkaline earth metal carboxylate salt to form ()--(aminomethyl)--methylhexanoic acid, wherein Rand Rare the same or different and are hydrogen, C-Calkyl, aryl, benzyl, or C-Ccycloalkyl. The present invention also provides a method of making ()--(aminomethyl)--methylhexanoic acid that comprises condensing isovaleraldehyde with to form primarily reacting the with a cyanide source to form decarboxylating the to form an alkali or alkaline earth metal carboxylate salt; and hydrogenating the alkali or alkaline earth metal carboxylate salt to form ()--(aminomethyl)--methylhexanoic acid.

Gaba And L-Glutamic Acid Analogs For Antiseizure Treatment

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US Patent:
20030225161, Dec 4, 2003
Filed:
Apr 28, 2003
Appl. No.:
10/424443
Inventors:
Richard Silverman - Morton Grove IL, US
Ryszard Andruszkiewicz - Sopot, PL
Denis Sobieray - Holland MI, US
Lloyd Franklin - Hamilton MI, US
Mark Schwindt - Holland MI, US
International Classification:
A61K031/195
C07C229/04
C07C229/32
C07C229/34
US Classification:
514/561000, 562/553000, 514/567000, 562/443000, 562/507000
Abstract:
A compound of the formula wherein Ris a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; Ris hydrogen or methyl; and Ris hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.

Gaba And L-Glutamic Acid Analogs For Antiseizure Treatment

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US Patent:
60282142, Feb 22, 2000
Filed:
Apr 21, 1998
Appl. No.:
9/063834
Inventors:
Richard B. Silverman - Morton Grove IL
Ryszard Andruszkiewicz - Sopot, PL
Denis Martin Sobieray - Holland MI
Lloyd Charles Franklin - Hamilton MI
Mark Alan Schwindt - Holland MI
Assignee:
Northwestern University - Evanston IL
Warner-Lambert Company - Ann Arbor MI
International Classification:
C07C 6966
US Classification:
560188
Abstract:
A compound of the formula ##STR1## wherein R. sub. 1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R. sub. 2 is hydrogen or methyl; and R. sub. 3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are also disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are further disclosed.
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Denis Martin Sobieray from Kalamazoo, MI, age ~66 Get Report