Samuel Sawan - Tyngsboro MA, US Tadmor Shalon - Palo Alto CA, US Dean Hung - Cupertino CA, US Norm Sokoloff - Los Altos Hills CA, US
International Classification:
A61K033/38 A61K031/155
US Classification:
424618000, 514636000
Abstract:
Methods of treatment for medical indications having a microbial etiology are provided using polybiguanides, particularly water insoluble and complexed with a water insoluble antimicrobial metal material. The compositions are contacted with mucosal or dermal tissue susceptible to infection or infected in an amount sufficient to inhibit proliferation and with a spaced-apart regimen due to the persistence of the composition.