Search

David John Tweardy

from Houston, TX
Age ~73
Get Report
Also known as:
David J Tweardy, David Dr Tweardy, Dave J Tweardy, David Falik
Phone and address:
3769 Nottingham St, Houston, TX 77005
(713) 664-5538
Related to:
Samuel David Tweardy, 37Daniel Tweardy, 31Ruth Falik, 75David E Boyes, 59Benjamin J Tweardy, 34
Connected to:
Lynne A Tweardy, 63Michael Tweardy, 59Robert G Tweardy, 60Dolores M Tweddale, 82Mark T Tweddale, 60Edward T Tweddell, 83Sarah C Tweddle, 30Darrel R Twede, 86Michael L Twede, 68Paul V Twede, 63

David Tweardy Phones & Addresses

  • 3769 Nottingham St, Houston, TX 77005 (713) 664-5538
  • 722 Shady Ave, Pittsburgh, PA 15232 (412) 441-6169
  • University Heights, OH
  • Philadelphia, PA

Work

Company: Houston Office Address: 1 Baylor Plz, Houston, TX 77030

Education

School / High School: Harvard Medical School 1978

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Infectious Disease, 1984

Specialities

Infectious Disease Medicine

Professional Records

License Records

David John Tweardy

Address:
Houston, TX 77005
License #:
MD031144E - Expired
Category:
Medicine
Type:
Medical Physician and Surgeon

Medicine Doctors

David Tweardy Photo 1

Dr. David J Tweardy - MD (Doctor of Medicine)

View page
Specialties:
Infectious Disease Medicine
Certifications:
Infectious Disease, 1984
Internal Medicine, 1983
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
1 Baylor Plz Suite N, Houston, TX 77030

6620 Main St, Houston, TX 77030

Houston Office
1 Baylor Plz, Houston, TX 77030

Ben Taub General Hospital
1504 Taub Loop, Houston, TX 77030

The Methodist Hospital
6565 Fannin Street, Houston, TX 77030
Education:
Medical School
Harvard Medical School
Graduated: 1978
Medical School
Case Western Res-U Clevelan
Graduated: 1978
David Tweardy Photo 2

David John Tweardy, Houston TX

View page
Specialties:
Internal Medicine
Infectious Disease
Adult Medicine
Work:
One Baylor Plaza
1 Baylor Plz, Houston, TX 77030
Bimc -General Internal Medicine Baylor Clinic
6620 Main St, Houston, TX 77030
Education:
Harvard University(1978)

Resumes

Resumes

David Tweardy Photo 3

Professor, Molecular And Cellular Oncology

View page
Location:
Houston, TX
Industry:
Hospital & Health Care
Work:
Md Anderson Cancer Center
Professor, Molecular and Cellular Oncology
Md Anderson Cancer Center
Head, Division of Internal Medicine
Baylor College of Medicin
Professor
Education:
Harvard Medical School 1975 - 1978
Doctor of Medicine, Doctorates, Medicine Princeton University 1970 - 1974
Bachelors, Bachelor of Arts, Chemistry
David Tweardy Photo 4

David Tweardy

View page
David Tweardy Photo 5

Professor At Baylor College Of Medicin

View page
Position:
Professor at Baylor College of Medicin
Location:
Houston, Texas Area
Industry:
Medical Practice
Work:
Baylor College of Medicin
Professor

Business Records

Name / Title
Company / Classification
Phones & Addresses
David Tweardy
STEMMED, LTD
Identification of New Cancer Drugs
7000 Fannin St STE 1960M, Houston, TX 77030
8100 Washington Ave, Houston, TX 77007
(713) 798-8908
David John Tweardy
David Tweardy MD
Internist
6620 Main St, Houston, TX 77030
(713) 798-2500

Publications

Us Patents

Stat3 Inhibitors

View page
US Patent:
20100041685, Feb 18, 2010
Filed:
Jun 3, 2009
Appl. No.:
12/477583
Inventors:
David J. Tweardy - Houston TX, US
Xuejun Xu - Missouri City TX, US
Moses M. Kasembeli - Houston TX, US
International Classification:
A61K 31/505
A61K 31/357
A61K 31/427
A61K 31/195
A61P 35/00
A61P 11/00
A61P 1/00
A61K 31/366
US Classification:
514274, 514452, 514369, 514562, 514456
Abstract:
Small molecule inhibitors of Stat3 and their derivatives are disclosed. Also described are methods to inhibit cell growth by use of Stat3 inhibitors, and the use of Stat3 inhibitors for the prevention and/or treatment of cancer. Further, inhibitors of Stat3 that also do not inhibit Stat1 are described as well as their derivatives. Methods of screening additional compounds for Stat3 inhibition activity and/or non-inhibition of Stat1 activity are also described herein.

Stat3 Inhibitors

View page
US Patent:
20110312984, Dec 22, 2011
Filed:
Jun 3, 2009
Appl. No.:
12/996073
Inventors:
David J. Tweardy - Houston TX, US
Wanzhi Huang - Houston TX, US
Moses M. Kasembeli - Houston TX, US
International Classification:
A61K 31/192
C12N 5/09
A61K 31/357
A61K 31/352
A61K 31/427
A61K 31/195
A61K 31/513
A61P 35/00
A61P 31/12
A61P 1/00
A61P 11/06
A61P 17/06
A61P 25/00
A61P 1/18
A61P 27/02
C12N 5/071
US Classification:
514274, 435375, 514452, 514457, 514369, 514562, 514569
Abstract:
Small molecule inhibitors of Stat3 and their derivatives are disclosed. Also described are methods to inhibit cell growth by use of Stat3 inhibitors, and the use of Stat3 inhibitors for the prevention and/or treatment of cancer. Further, inhibitors of Stat3 that also do not inhibit Stat1 are described as well as their derivatives. Methods of screening additional compounds for Stat3 inhibition activity and/or non-inhibition of Stat1 activity are also described herein.

Structural Requirements For Stat3 Binding And Recruitment To Phosphotyrosine Ligands

View page
US Patent:
20060148715, Jul 6, 2006
Filed:
Dec 20, 2005
Appl. No.:
11/313104
Inventors:
David Tweardy - Houston TX, US
Assignee:
BAYLOR COLLEGE OF MEDICINE - Houston TX
International Classification:
A61K 38/10
US Classification:
514014000
Abstract:
Inhibitors of Stat3 are disclosed, including small molecules and peptide mimetic inhibitors. Specific Stat3 inhibitors of the invention are useful as beta-turn mimetics. Also disclosed are pharmaceutical compositions of the Stat3 inhibitors of the invention, and methods for using the compounds of the invention to inhibit growth of a cell or to inhibit protein-protein interactions modulated by SH2 domains. Methods of screening for Stat3 inhibitors are also provided.

Therapeutic Compounds For Methods Of Use In Insulin Resistance

View page
US Patent:
20230077280, Mar 9, 2023
Filed:
Dec 3, 2020
Appl. No.:
17/781349
Inventors:
- Houston TX, US
David J. Tweardy - Houston TX, US
Imran Alibhai - Sugar Land TX, US
Sofia de Achaval - Missouri City TX, US
International Classification:
A61K 31/18
A61P 3/10
A61K 45/06
Abstract:
Embodiments of the disclosure encompass methods of treating insulin resistance in an individual in need thereof by administering one or more STAT3 inhibitors to the individual. In specific aspects, the methods allow for reversing insulin resistance in individuals. The STAT3 inhibitor may be one or more particular small molecules encompassed herein.

Methods For Measuring And Stabilizing Stat3 Inhibitors

View page
US Patent:
20210235688, Aug 5, 2021
Filed:
Apr 17, 2019
Appl. No.:
17/048707
Inventors:
David J. TWEARDY - Houston TX, US
David KWOK - Vancouver, CA
Assignee:
Board of Regents, The University of Texas System - Austin TX
International Classification:
A01N 1/02
G01N 33/94
Abstract:
Methods for stabilizing Stat3 inhibitors in a blood sample are provided. Methods for assessing the level of such Stat3 inhibitors are also provided.

Stat3 Inhibitors

View page
US Patent:
20210114980, Apr 22, 2021
Filed:
Apr 18, 2019
Appl. No.:
17/048602
Inventors:
- Houston TX, US
David John TWEARDY - Houston TX, US
International Classification:
C07C 311/29
Abstract:
Compounds as STAT3 inhibitors are described. A pharmaceutical composition comprising the same, methods of making the same, and a method for treating or preventing conditions such as cancer, chronic inflammation, and fibrosis using the same, are described.

Stat3 Inhibitors

View page
US Patent:
20210038544, Feb 11, 2021
Filed:
Oct 22, 2020
Appl. No.:
17/077821
Inventors:
- Houston TX, US
David John Tweardy - Houston TX, US
International Classification:
A61K 31/18
Abstract:
Compounds as STAT3 inhibitors are described. A pharmaceutical composition comprising the same, methods of making the same, and a method for treating or preventing conditions such as cancer, chronic inflammation, and fibrosis using the same, are described.
Control profile
David John Tweardy from Houston, TX, age ~73 Get Report