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Daniel M Retz

from Yorba Linda, CA
Age ~62
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Also known as:
Daniel Martin Retz, Daniel M V Ketz, Daniel M Reiz, Daniel M Ritz, Wendy Retz
Phone and address:
5964 Jacaranda Ln, Yorba Linda, CA 92887
(714) 970-0121
Related to:
Iliana Fernandez, 70Daniel Fernandez, 40Joanna I LaneaveVinh Hoang, 55Minh L Hoang, 70
Connected to:
Denise K Retz, 38Jayne Retz, 58Jill K Retz, 57Keith P Retz, 93Roger E Retz, 85Wendy A Retz, 57Andrew Retzer, 34Duane C Retzer, 81Jeffery M Retzer, 57Shawn C Retzer, 49

Daniel Retz Phones & Addresses

  • 5964 Jacaranda Ln, Yorba Linda, CA 92887 (714) 970-0121
  • Henderson, NV
  • 201 Longfellow St, Thousand Oaks, CA 91360 (805) 493-5111
  • 736 Camino Manzanas, Thousand Oaks, CA 91360 (805) 375-5894
  • Newbury Park, CA
  • Manzanita, CA
  • 4761 Whitesell Dr, Troy, MI 48007 (248) 680-9165
  • Orange, CA
  • Ventura, CA
  • 5964 Jacaranda Ln, Yorba Linda, CA 92887 (805) 493-5111

Work

Position: Service Occupations

Education

Degree: Associate degree or higher

Emails

t***[email protected]

Resumes

Resumes

Daniel Retz Photo 1

Senior Research Scientist

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Location:
5964 Jacaranda Ln, Yorba Linda, CA 92887
Industry:
Pharmaceuticals
Work:
Moravek Biochemicals Inc
Senior Research Scientist
Amgen 1997 - 2007
Senior Research Associate
Parke Davis Pharmaceuticals Division of Warner Lambert Oct 1988 - Apr 1997
Senior Research Associate
Education:
The Ohio State University 1985 - 1988
Master of Science, Masters, Organic Chemistry Andrews University 1981 - 1985
Bachelors, Bachelor of Science, Chemistry
Skills:
Drug Discovery
Drug Development
Medicinal Chemistry
Purification
Languages:
English
Daniel Retz Photo 2

Daniel Retz

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Publications

Us Patents

Aminopyrimidine Compounds And Methods Of Use

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US Patent:
7786132, Aug 31, 2010
Filed:
Dec 16, 2005
Appl. No.:
11/304901
Inventors:
Adrian Leonard Smith - Simi Valley CA, US
Paul Edward Brennan - Littlebourne, GB
Frenel Fils DeMorin - Thousand Oaks CA, US
Gang Liu - Oak Park CA, US
Nick A. Paras - Santa Monica CA, US
Daniel Martin Retz - Thousand Oaks CA, US
Elizabeth Rainbeau - Port Hueneme CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07D 409/14
C07D 417/14
A61K 31/506
A61P 19/02
A61P 35/00
US Classification:
514269, 514275, 514256, 544316, 544331, 544333
Abstract:
The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation.

Aminopyrimidine Compounds And Methods Of Use

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US Patent:
7858785, Dec 28, 2010
Filed:
Sep 18, 2009
Appl. No.:
12/562853
Inventors:
Adrian Leonard Smith - Simi Valley CA, US
Paul Edward Brennan - Canterbury, GB
Fenel F. Fils - Thousand Oaks CA, US
Gang Liu - Oak Park CA, US
Nick A. Paras - Glendale CA, US
Daniel Martin Retz - Newbury Park CA, US
Elizabeth Rainbeau - Port Hueneme CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07D 417/14
A61K 31/506
A61P 19/02
A61P 35/00
US Classification:
544316, 544331, 544333, 514275, 514256, 514269
Abstract:
The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation.

Substituted Pyrimidine Compounds As Raf Inhibitors And Methods Of Use

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US Patent:
8440674, May 14, 2013
Filed:
Jun 17, 2011
Appl. No.:
13/163666
Inventors:
Frenel F. De Morin - Thousand Oaks CA, US
Jian J. Chen - Camarillo CA, US
Elizabeth M. Doherty - Thousand Oaks CA, US
Stephen A. Hitchcock - Juniper FL, US
Qi Huang - Moorpark CA, US
Joseph L. Kim - Wayland MA, US
Gang Liu - Oak Park CA, US
Thomas Nixey - Newbury Park CA, US
Nick A. Paras - San Francisco CA, US
Jeffrey Petkus - Reseda CA, US
Daniel Martin Retz - Yorba Linda CA, US
Adrian Leonard Smith - Simi Valley CA, US
Jiawang Zhu - Shanghai, CN
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A01N 43/54
US Classification:
514256, 544242, 544283, 546148, 546152, 5462681, 548152, 548247, 5483731, 548469, 549398
Abstract:
The present invention comprises a new class of compounds capable of modulating Raf kinase and, accordingly, useful for treatment of Raf kinase mediated diseases, including melanomas, tumors and other cancer-related conditions. The compounds have a general Formula I.

Substituted Heterocyclic Compounds And Methods Of Use

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US Patent:
20060069110, Mar 30, 2006
Filed:
Sep 27, 2005
Appl. No.:
11/237513
Inventors:
Denise Andersen - Simi Valley CA, US
Catherine Chang - Ann Arbor MI, US
James Falsey - Moorpark CA, US
Michael Frohn - Thousand Oaks CA, US
Hongyu Liao - Thousand Oaks CA, US
Longbin Liu - Thousand Oaks CA, US
Patricia Lopez - West Hills CA, US
Daniel Retz - Thousand Oaks CA, US
Gilbert Rishton - Malibu CA, US
Robert Rzasa - Ventura CA, US
Aaron Siegmund - Oxnard CA, US
Seifu Tadesse - Simi Valley CA, US
Nuria Tamayo - Newbury Park CA, US
Christopher Tegley - Thousand Oaks CA, US
International Classification:
A61K 31/506
C07D 403/14
C07D 403/04
US Classification:
514275000, 544296000, 544328000
Abstract:
The present invention relates to pyridines, pyrimidines and derivatives thereof, and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic β cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.

Vanilloid Receptor Ligands And Their Use In Treatments

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US Patent:
20060235036, Oct 19, 2006
Filed:
Apr 17, 2006
Appl. No.:
11/406437
Inventors:
Elizabeth Doherty - Thousand Oaks CA, US
Hongyu Liao - Thousand Oaks CA, US
Mark Norman - Thousand Oaks CA, US
Daniel Retz - Thousand Oaks CA, US
International Classification:
A61K 31/506
A61K 31/501
C07D 403/14
US Classification:
514275000, 514252050, 544238000, 544329000
Abstract:
Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

Vanilloid Receptor Ligands And Their Use In Treatments

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US Patent:
20060241296, Oct 26, 2006
Filed:
Apr 25, 2006
Appl. No.:
11/411366
Inventors:
Elizabeth Doherty - Thousand Oaks CA, US
Jodie Katon - Woodland Hills CA, US
Mark Norman - Thousand Oaks CA, US
Daniel Retz - Thousand Oaks CA, US
Xianghong Wang - Moorpark CA, US
Yunxin Bo - Thousand Oaks CA, US
Nuria Tamayo - Newbury Park CA, US
Nobuko Nishimura - West Hills CA, US
Hongyu Liao - Thousand Oaks CA, US
International Classification:
A61K 31/506
C07D 403/02
US Classification:
544295000, 544324000, 544331000
Abstract:
Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

Nitrogen-Containing Bicyclic Heteroaryl Compounds And Methods Of Use

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US Patent:
20070185324, Aug 9, 2007
Filed:
Dec 20, 2006
Appl. No.:
11/643261
Inventors:
Frenel De Morin - Thousand Oaks CA, US
Jian Chen - , US
Elizabeth Doherty - Thousand Oaks CA, US
Stephen Hitchcock - Westlake Village CA, US
Qi Huang - Moorpark CA, US
Joseph Kim - Wayland MA, US
Gang Liu - Oak Park CA, US
Thomas Nixey - Newbury Park CA, US
Nick Paras - Thousand Oaks CA, US
Jeffrey Petkus - Reseda CA, US
Daniel Retz - Newbury Park CA, US
Adrian Smith - Simi Valley CA, US
Andrew Tasker - Simi Valley CA, US
Jiawang Zhu - Thousand Oaks CA, US
International Classification:
A61K 31/541
A61K 31/5377
C07D 417/02
C07D 403/02
US Classification:
544060000, 544255000, 544257000, 544279000, 544296000, 544120000, 544324000, 544295000, 544238000, 544284000
Abstract:
The present invention comprises a new class of compounds capable of modulating Raf kinase and, accordingly, useful for treatment of Raf kinase mediated diseases, including melanomas, tumors and other cancer-related conditions. The compounds have a general Formula I wherein Ris and A, A, A, A, X, Z, Z′, R, R, R, R, Rand Rare defined herein. The invention further comprises pharmaceutical compositions, methods for treatment of Raf kinase mediated diseases, and intermediates and processes useful for the preparation of compounds of the invention.
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Daniel M Retz from Yorba Linda, CA, age ~62 Get Report