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Dale P Devore

from Chelmsford, MA
Age ~82

Dale Devore Phones & Addresses

  • 3 Warwick Dr, Chelmsford, MA 01824 (978) 250-0728
  • Hartsel, CO
  • Las Vegas, NV
  • Westerly, RI
  • Decatur, GA
  • Acton, MA

Resumes

Resumes

Dale Devore Photo 1

Owner, Dv Consulting

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Location:
Chelmsford, MA
Industry:
Medical Devices
Work:
Euclid Systems Corp.
Chief Strategy Officer

Bioform Medical 2004 - 2008
Vice President of R and D

Collagenesis 1996 - 2001
Chief Strategy Officer

Dv Consulting 1996 - 2001
Owner, Dv Consulting
Education:
Rutgers University
Doctorates, Doctor of Philosophy, Biochemistry
Skills:
Medical Devices
Lifesciences
Commercialization
Clinical Trials
Biotechnology
Fda
Market Development
Iso 13485
Technology Transfer
Healthcare
Product Development
Pharmaceutical Industry
Surgery
R&D
Start Ups
Regulatory Affairs
Design Control
Biomedical Engineering
Clinical Development
Life Sciences
Clinical Research
Orthopedic
Capital Equipment
Product Launch
Business Development
Tissue Engineering
Biomaterials
Dale Devore Photo 2

Dale Devore

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Dale Devore Photo 3

Dale Devore

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Dale Devore Photo 4

Dale Devore

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Dale Devore Photo 5

Dale Devore

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Business Records

Name / Title
Company / Classification
Phones & Addresses
Dale Devore
Owner
Xium
Business Services at Non-Commercial Site
3 Warwick Dr, Kates Corner, MA 01824
Dale Devore
President, Secretary, Treasurer
Infrastructures, Inc
PO Box 27740, Las Vegas, NV 89126

Publications

Us Patents

Compound Delivery Using Rapidly Dissolving Collagen Film

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US Patent:
6448378, Sep 10, 2002
Filed:
Dec 12, 2000
Appl. No.:
09/735182
Inventors:
Dale P. DeVore - Chelmsford MA, 01824
Richard A. Eiferman - Louisville KY, 40207
Edwin U. Keates - Villanova PA, 19085
International Classification:
A61K 3817
US Classification:
530356, 530342, 530345, 530402, 514 2, 514 21, 514801, 514912, 514913
Abstract:
Disclosed herein are collagen films which rapidly dissolve at 35Â C. Also disclosed are methods for the preparation of the collagen films and their use as a vehicle for delivering a dose of therapeutic compound to a specific tissue site.

Processing Animal Tissues By Decellularizing, Increasing Surface Area And Acylating

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US Patent:
6743435, Jun 1, 2004
Filed:
Aug 28, 2001
Appl. No.:
09/941438
Inventors:
Dale P. DeVore - Chelmsford MA
Peter D. Ciarametaro - Gloucester MA
Assignee:
Collagen Matrix Technologies, Inc. - Boca Raton FL
International Classification:
A61F 200
US Classification:
424423, 435 11, 530353, 530356, 530402
Abstract:
Methods are provided for processing and dispersing animal tissues that involve exposing processed (e. g. , decellularized) tissue to an acylating agent, wherein the ratio of acylating agent to wet tissue weight is about 0. 003:1 or less. Preferably, decellularized tissue is exposed to an amount of the acylating agent of about 0. 1% to about 0. 3% of wet tissue weight for a time ranging from about 30 seconds to about 10 minutes. A dispersed tissue matrix is produced that has a high degree of resistance to digestion by non-collagenase proteases, such as trypsin. In order to produce sufficiently high yields of these trypsin-resistant compositions, the processed tissue is preferably cryomilled to increase its surface area prior to acylation. The dispersed acylated decellularized tissue may be in the form of an injectable composition that can be introduced into tissue of a subject.

Light Energized Tissue Adhesive Conformal Patch

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US Patent:
6773699, Aug 10, 2004
Filed:
Oct 9, 2001
Appl. No.:
09/973385
Inventors:
Barbara A. Soltz - Spring Valley NY
Dale P. DeVore - Chelmsford MA
Braden P. DeVore - Westerly RI
Robert Soltz - Spring Valley NY
Michael A. Soltz - Pleasanton CA
Assignee:
Tissue Adhesive Technologies, Inc. - Spring Valley NY
International Classification:
A61K 3800
US Classification:
424 7803, 424426, 424486, 530356, 606213, 606229
Abstract:
Consistent with the present invention, tissue adhesive compositions and an associated laser exposure system are provided for bonding or sealing biological tissues. The compositions are comprised of chemically derivatized soluble collagen which is formulated to concentrations ranging from 300 mg/ml (30%) to 80 mg/ml (80%) collagen protein. In particular, Type I collagen, for example, is first prepared by extraction from bovine or porcine hide and purified. The collagen preparations are then chemically derivatized with sulfhydryl reagents to improve cohesive strength and with secondary derivatizing agents, such as carboxyl groups, to improve the adhesive strength of the solder to the tissue. The compositions are then formed into viscous solutions, gels or solid films which are used to encapsulate structural components such as a cojoinal network or mesh. The resultant patch which when exposed to energy generated from an infrared laser, for example, undergo thermally induced phase transitions. Solid or semi-solid protein compositions become less viscous enabling the high concentration protein to penetrate the interstices of treated biological tissue or to fill voids in tissue.

Method For Making A Light Energized Tissue Adhesive

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US Patent:
6780840, Aug 24, 2004
Filed:
Oct 9, 2001
Appl. No.:
09/973263
Inventors:
Dale P. DeVore - Chelmsford MA
Braden P. DeVore - Westerly RI
Barbara A. Soltz - Spring Valley NY
Robert Soltz - Spring Valley NY
Michael A. Soltz - Pleasanton CA
Assignee:
Tissue Adhesive Technologies, Inc. - Spring Valley NY
International Classification:
A61K 3800
US Classification:
514 2, 522 68, 530356, 424 7803, 128898
Abstract:
Consistent with the present invention, tissue adhesive compositions and an associated laser exposure system are provided for bonding or sealing biological tissues. The compositions are comprised of chemically derivatized soluble collagen which is formulated to concentrations ranging from 300 mg/ml (30%) to 800 mg/ml (80%) collagen protein. In particular, Type I collagen, for example, is first prepared by extraction from bovine or porcine hide and purified. The collagen preparations are then chemically derivatized with sulfhydryl reagents to improve cohesive strength and with secondary derivatizing agents, such as carboxyl groups, to improve the adhesive strength of the solder to the tissue. The compositions are then formed into viscous solutions, gels or solid films, which when exposed to energy generated from an infrared laser, for example, undergo thermally induced phase transitions. Solid or semi-solid protein compositions become less viscous enabling the high concentration protein to penetrate the interstices of treated biological tissue or to fill voids in tissue.

Light Energized Tissue Adhesive

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US Patent:
6875427, Apr 5, 2005
Filed:
Oct 9, 2001
Appl. No.:
09/973332
Inventors:
Dale P. DeVore - Chelmsford MA, US
Braden P. DeVore - Westerly RI, US
Barbara A. Soltz - Spring Valley NY, US
Robert Soltz - Spring Valley NY, US
Michael A. Soltz - Pleasanton CA, US
Assignee:
Tissue Adhesive Technologies, Inc. - Spring Valley NY
International Classification:
A61K038/00
US Classification:
424 7803, 522 68, 514526, 128898
Abstract:
Consistent with the present invention, tissue adhesive compositions and an associated laser exposure system are provided for bonding or sealing biological tissues. The compositions are comprised of chemically derivatized soluble collagen which is formulated to concentrations ranging from 300 mg/ml (30%) to 800 mg/ml (80%) collagen protein. In particular, Type I collagen, for example, is first prepared by extraction from bovine or porcine hide and purified. The collagen preparations are then chemically derivatized with sulfhydryl reagents to improve cohesive strength and with secondary derivatizing agents, such as carboxyl groups, to improve the adhesive strength of the solder to the tissue. The compositions are then formed into viscous solutions, gels or solid films, which when exposed to energy generated from an infrared laser, for example, undergo thermally induced phase transitions. Solid or semi-solid protein compositions become less viscous enabling the high concentration protein to penetrate the interstices of treated biological tissue or to fill voids in tissue.

Composite Tissue Adhesive

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US Patent:
6939364, Sep 6, 2005
Filed:
Oct 9, 2001
Appl. No.:
09/973335
Inventors:
Barbara A. Soltz - Spring Valley NY, US
Dale P. DeVore - Chelmsford MA, US
Braden P. DeVore - Westerly RI, US
Robert Soltz - Spring Valley NY, US
Michael A. Soltz - Pleasanton CA, US
Assignee:
Tissue Adhesive Technologies, Inc. - Spring Valley NY
International Classification:
A61B017/03
US Classification:
606214, 424422, 606213, 606215
Abstract:
Consistent with the present invention, tissue adhesive compositions and an associated laser exposure system are provided for bonding or sealing biological tissues. The compositions are comprised of chemically derivatized soluble collagen which is formulated to concentrations ranging from 300 mg/ml (30%) to 800 mg/ml (80%) collagen protein. In particular, Type I collagen, for example, is first prepared by extraction from bovine or porcine hide and purified. The collagen preparations are then chemically derivatized with sulfhydryl reagents to improve cohesive strength and with secondary derivatizing agents, such as carboxyl groups, to improve the adhesive strength of the solder to the tissue. The compositions are then formed into viscous solutions, gels or solid films, which when exposed to energy generated from an infrared laser, for example, undergo thermally induced phase transitions. Solid or semi-solid protein compositions become less viscous enabling the high concentration protein to penetrate the interstices of treated biological tissue or to fill voids in tissue.

Preparation Of Hyaluronic Acid From Eggshell Membrane

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US Patent:
6946551, Sep 20, 2005
Filed:
Jul 9, 2003
Appl. No.:
10/616278
Inventors:
Frank Daniel Long - Neosho MO, US
Randall Gene Adams - Carthage MO, US
Dale Paul DeVore - Chelmsford MA, US
Assignee:
New Life Resources, LLC - Carthage MO
International Classification:
A61K031/728
C08B037/00
US Classification:
536 553, 514 53, 514 54, 536 551, 536 552
Abstract:
Compositions and methods of preparing compositions containing hyaluronic acid derived from eggshell membrane are disclosed. The compositions can contain essentially pure hyaluronic acid or hyaluronic acid in combination with other naturally occurring constituents derived from eggshell membrane. In another aspect, the invention is directed to a method of treating a mammal that will benefit from the administration of hyaluronic acid, which includes administering to the mammal a composition containing hyaluronic acid derived from eggshell membrane.

Method For Localized Staining Of An Intact Corneal Tissue Surface

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US Patent:
7015013, Mar 21, 2006
Filed:
May 14, 2004
Appl. No.:
10/846742
Inventors:
Dale Paul DeVore - Chelmsford MA, US
Braden Patrick DeVore - Las Vegas NV, US
Assignee:
3D Vision Systems, LLC - Norwood MA
International Classification:
G01N 1/30
US Classification:
435 405, 435 30
Abstract:
The present disclosure describes novel methods for localized and controlled staining of intact corneal tissue surfaces to provide therapeutic benefits in ophthalmic applications, such as for example, the correction of iris defects, the correction of corneal tissue scarring, and the creation of a pupil in aniridia. A first method for staining tissue surfaces is directed to covalently bonding sulfonic acid dyes to deprotonated proteins in tissue. Another disclosed method is directed to staining corneal tissue surfaces with black sulfonic acid dye compositions, particularly for forming black rings on the corneal surface.
Dale P Devore from Chelmsford, MA, age ~82 Get Report