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Cyrille F Kuhn

from Ridgefield, CT
Age ~58

Cyrille Kuhn Phones & Addresses

  • 20 Silver Brook Rd, Ridgefield, CT 06877 (203) 403-5200
  • 10 Murdock St, Somerville, MA 02145
  • 51 Forest St, Winchester, MA 01890
  • Cambridge, MA
  • Frazee, MN

Work

Company: Boehringer ingelheim Jun 2015 Position: Head of research beyond borders

Education

School / High School: Dyson School of Design Engineering 1996 to 1997 Specialities: Chemistry

Skills

Drug Discovery • Organic Chemistry • Medicinal Chemistry • Drug Design • Pharmaceutical Industry • Lead Change • Analytical Chemistry • Purification • R&D • Parallel Synthesis • Pharmaceutical Research

Industries

Pharmaceuticals

Resumes

Resumes

Cyrille Kuhn Photo 1

Head Of Research Beyond Borders

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Location:
2001 Manufacturing Ct, Clinton, IA 52732
Industry:
Pharmaceuticals
Work:
Boehringer Ingelheim
Head of Research Beyond Borders

Boehringer Ingelheim Jan 2013 - Jun 2015
Executive Director Research Networking and Strategic Planning

Boehringer Ingelheim Sep 2008 - Dec 2012
Director Parallel Chemistry Lead Discovery

Aeres Groep 2011 - 2011
International Expert

Anr (Agence Nationale De La Recherche) 2011 - 2011
International Expert
Education:
Dyson School of Design Engineering 1996 - 1997
Université Paris Descartes 1992 - 1996
Doctorates, Doctor of Philosophy, Chemistry
Sorbonne Université 1987 - 1991
Bachelors, Bachelor of Science, Chemistry
Skills:
Drug Discovery
Organic Chemistry
Medicinal Chemistry
Drug Design
Pharmaceutical Industry
Lead Change
Analytical Chemistry
Purification
R&D
Parallel Synthesis
Pharmaceutical Research

Publications

Us Patents

Quinoline Derivatives As Crth2 Antagonists

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US Patent:
20040132772, Jul 8, 2004
Filed:
Oct 17, 2003
Appl. No.:
10/688566
Inventors:
Mohamed Awad - Groton CT, US
Marc Bazin - Cedex, FR
Frederic Feru - Cedex, FR
Steven Goldstein - Groton CT, US
Cyrille Kuhn - Cambridge MA, US
International Classification:
A61K031/4709
A61K031/47
G01N033/53
G01N033/569
C07D215/38
US Classification:
514/313000, 546/159000, 435/007310
Abstract:
The invention relates to compounds of formula (I) wherein R, R, R, R, R, R, Rand Rare as defined in the description, their use as medicament, pharmaceutical compositions containing them and processes for their preparation.

Quinoline Derivatives As Crth2 Antagonists

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US Patent:
20070197587, Aug 23, 2007
Filed:
Apr 16, 2007
Appl. No.:
11/735686
Inventors:
Mohamed Ali Awad - Groton CT, US
Marc Bazin - Fresnes, FR
Frederic Feru - Fresnes, FR
Steven Goldstein - Groton CT, US
Cyrille Kuhn - Cambridge MA, US
International Classification:
A61K 31/47
US Classification:
514312000, 514313000
Abstract:
The invention relates to compounds of formula (I) wherein R, R, R, R, R, R, Rand Rare as defined in the description, their use as medicament, pharmaceutical compositions containing them and processes for their preparation.

Respiratory Syncytial Virus Inhibitors

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US Patent:
20190002436, Jan 3, 2019
Filed:
Jul 28, 2016
Appl. No.:
15/748606
Inventors:
- Stockholm, SE
Karolina ERSMARK - Huddinge, SE
Gennadiy KALAYANOV - Bandhagen, SE
Marie LEIJONMARCK - Hagersten, SE
Lourdes Salvador ODEN - Huddinge, SE
Hans WESTERLIND - Saltsjobaden, SE
Horst WAHLING - Huddinge, SE
Megan BERTRAND - Laval, CA
Christian BROCHU - Burlington, CA
Elise GHIRO - Laval, CA
Cyrille KUHN - Ridgefield CT, US
Claudio STURINO - Burlington, CA
Johan BYLUND - Huddinge, SE
Fernando SEHGELMEBLE - Huddinge, SE
Stina LUNDGREN - Huddinge, SE
International Classification:
C07D 401/14
C07D 471/04
C07D 471/10
C07D 471/20
C07D 487/10
A61P 31/14
Abstract:
Compounds of Formula (I): (Formula I), wherein Zis NR, CHR, CRR; one of Zand Zis CH or CR, the other is N, CH or CR; n is 0, 1 or 2; q is 0, 1 or 2; R, R, R, R, and Rare as defined herein, their use as inhibitors of RSV and related aspects.

Respiratory Syncytial Virus Inhibitors

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US Patent:
20160272646, Sep 22, 2016
Filed:
Oct 29, 2013
Appl. No.:
15/032855
Inventors:
- Stockholm, SE
Teddy HALMOS - Burlington, CA
Anne DECOR - Burlington, CA
Martin DUPLESSIS - Burlington, CA
Patrick DEROY - Burlington, CA
Araz JAKALIAN - Burlington, CA
Louis MORENCY - Burlington, CA
Cyrille KUHN - Ridgefield CT, US
Chantal GRAND-MAITRE - Burlington, CA
Martin TREMBLAY - Burlington, CA
Christian BROCHU - Burlington, CA
International Classification:
C07D 487/04
C07D 405/14
C07D 413/14
C07D 471/04
C07D 413/06
C07D 403/06
C07D 473/06
C07D 401/06
C07D 471/14
C07D 401/14
C07D 403/14
Abstract:
Compounds of Formula (I), wherein R, R, R, Rand n are defined herein, are useful as inhibitors of RSV.

Hepatitis C Inhibitor Compounds

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US Patent:
20150291592, Oct 15, 2015
Filed:
Aug 22, 2012
Appl. No.:
14/240636
Inventors:
- Ingelheim, DE
Chantal Grand-Maitre - Laval, CA
Marc-Andre Joly - Terrebonne, CA
Cyrille Kuhn - Ridgefield CT, US
Megan Bertrand-Laperle - Laval, CA
Marc Pesant - Laval, CA
Assignee:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH - Ingelheim am Rhein
International Classification:
C07D 487/04
A61K 31/4162
A61K 31/4545
A61K 31/4245
A61K 31/4196
A61K 31/4439
A61K 31/497
Abstract:
Compounds of Formula (I) wherein n, X, X, R, R, Y, Yand Rare defined herein, are useful for the treatment of hepatitis C viral infection.

Hepatitis C Inhibitor Compounds

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US Patent:
20140343077, Nov 20, 2014
Filed:
Aug 22, 2012
Appl. No.:
14/240641
Inventors:
Christian Brochu - Blainville, CA
Chantal Grand-Maitre - Boisbriand, CA
Lee Fader - New Milford CT, US
Cyrille Kuhn - Ridgefield CT, US
Megan Bertrand-Laperle - Laval, CA
Marc Pesant - Saint Colomban, CA
Assignee:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH - Ingelheim am Rhein
International Classification:
C07D 471/04
A61K 31/4439
C07D 405/12
A61K 31/403
C07D 403/12
A61K 31/4178
C07D 409/12
C07D 417/14
A61K 31/433
C07D 403/14
A61K 31/4196
A61K 31/437
A61K 31/4155
A61K 31/497
A61K 45/06
C07D 401/14
US Classification:
51425505, 5462767, 514339, 548448, 514411, 5483114, 514385, 548138, 514363, 5482664, 514383, 548407, 514409, 546 86, 514292, 5483647, 514406, 544405
Abstract:
A compound of formula (I) useful for the treatment or prevention of hepatitis C viral infection, (Formula (I)) wherein: Xand Xare each independently CRor N; Ris H, (C)alkyl, (C)haloalkyl, halo. —O—(C)alkyl, NH, NH(C)alkyl or N((C)alkyl); Rand Rare each independently (C)alkyl optionally mono- or di-substituted with —O—(C)alkyl, NH, NH(C)alkyl or N((C)alkyl); or Rand R, together with the carbon to which they are attached, are linked to form a (C)cycloalkyl group or a 3- to 7-membered heterocyclyl, said cycloalkyl and heterocyclyl being optionally mono- or di-substituted with —(C)alkyl; Ris —C(═O)N(R)(R), —C(═O)O(R), heterocyclyl or heteroaryl, wherein each said heterocyclyl and heteroaryl is optionally substituted 1 to 3 times with R; Rand Rare each independently H or (C)alkyl optionally mono- or di-substituted with —O—(C)alkyl, NH, NH(C)alkyl or N((C)alkyl); or Rand R, together with the carbon to which they are attached, are linked to form a (C)cycloalkyl group or a 3- to 7-membered heterocyclyl, said cycloalkyl and heterocyclyl being optionally mono- or di-substituted with —(C)alkyl; and n is 0, 1 or 2.
Cyrille F Kuhn from Ridgefield, CT, age ~58 Get Report