Clayton L Casipit

58887750, Mar 30, 1999

Apr 29, 1994

8/235178

Rony Tal - Coral Springs FL
Hing C. Wong - Ft. Lauderdale FL
Clayton Casipit - Hialeah FL
Pierre-Andre Chavaillaz - Cooper City FL
Vaughan Wittman - Ft. Lauderdale FL

Dade International Inc - Deerfield IL

A61K 3900
C12N 1562
C07K 100
C07K 1900

435 697

The present invention provides novel methods for the synthesis and isolation and purification of a peptide of interest (target peptide). In particular, the invention relates to peptide synthesis, isolation and purification methods that comprise use of penI fusion polypeptides and related gene fusion constructs that encode such polypeptides.

57632847, Jun 9, 1998

Apr 25, 1995

8/428733

Rony Tal - Coral Springs FL
Hing C. Wong - Ft. Lauderdale FL
Clayton Casipit - Hialeah FL
Pierre-Andre Chavaillaz - Cooper City FL
Vaughan Wittman - Ft. Lauderdale FL

Dade International Inc. - Deerfield IL

G01N 3353
G01N 33536
G01N 3368
C12N 1562

436501

The present invention provides novel methods for the synthesis and isolation and purification of a peptide of interest (target peptide). In particular, the invention relates to peptide synthesis, isolation and purification methods that comprise use of penI fusion polypeptides and related gene fusion constructs that encode such polypeptides.

56440359, Jul 1, 1997

Jun 7, 1995

8/477674

Kirston E. Koths - El Cerrito CA
Robert F. Halenbeck - San Rafael CA
Eric W. Taylor - Berkeley CA
Alice M. Wang - Lafayette CA
Clayton L. Casipit - Hayward CA

Chiron Corporation - Emeryville CA

C07K 100
B01D 1508

530395

A purified glycoprotein complex of over 1200 kD apparent native molecular weight having a sedimentation value of approximately 25S and having the ability to selectively bind human Mac-2 or interfere with PHA activation of lymphocytes, DNA sequences that encode the protein, and expression systems for expressing it, thus providing for medicaments that are useful for treating or diagnosing diseases, including cancer, infectious disease, and diseases of the immune system.

59653825, Oct 12, 1999

Sep 29, 1994

8/316714

Kirston E. Koths - El Cerrito CA
Robert F. Halenbeck - San Rafael CA
Eric W. Taylor - Berkeley CA
Alice M. Wang - Lafayette CA
Clayton L. Casipit - Hayward CA

Chiron Corporation - Emeryville CA

C12N 1512

435 691

A purified glycoprotein complex of over 1200 kD apparent native molecular weight having a sedimentation value of approximately 25S and having the ability to selectively bind human Mac-2 or interfere with PHA activation of lymphocytes, DNA sequences that encode the protein, and expression systems for expressing it, thus providing for medicaments that are useful for treating or diagnosing diseases, including cancer, infectious disease, and diseases of the immune system.

61275247, Oct 3, 2000

Oct 18, 1996

8/732708

Clayton L. Casipit - Hialeah FL
Hing C. Wong - Fort Lauderdale FL
Bee Y. Huang - Fort Lauderdale FL

Dade Behring Inc. - Deerfield IL

A61K 39395

5303873

The present invention features novel binding molecules and methods of improving the specific binding affinity of binding molecules, which methods do not use X-ray crystallography. For example, in one aspect, the invention features methods of making antibodies with improved specific binding affinity for a polypeptide produced during prothrombin activation. The present invention is useful for a variety of applications including, e. g. , producing binding molecules with improved binding affinity; and screening for binding molecules which are in low abundance.

57363404, Apr 7, 1998

Jun 7, 1995

8/473791

Kirston E. Koths - El Cerrito CA
Robert F. Halenbeck - San Rafael CA
Eric W. Taylor - Berkeley CA
Alice M. Wang - Lafayette CA
Clayton L. Casipit - Hayward CA

Chiron Corporation - Emeryville CA

G01N 3353

435 71

A purified glycoprotein complex of over 1200 kD apparent native molecular weight having a sedimentation value of approximately 25S and having the ability to selectively bind human Mac-2 or interfere with PHA activation of lymphocytes, DNA sequences that encode the protein, and expression systems for expressing it, thus providing for reagents that are useful for treating or diagnosing diseases, including cancer, infectious disease, and diseases of the immune system, and for monitoring the concentration of the glycoprotein in human milk.