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Claudia L Averbuj

from San Diego, CA
Age ~58
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Also known as:
Claudia Col Averbuj, Claudia C Averbuj, Claudia J
Phone and address:
13125 Sunset Point Way, San Diego, CA 92130
(858) 259-9271
Related to:
Alon Averbuj, 27Dan Averbuj, 31Anita AverbujRoberto F Averbuj, 60Abraham Averbuj
Connected to:
Timothy D Averch, 61Colleen Averdick, 47Amanda L Averell, 40Gatton Averell, 38Jessica K Averello, 31Leann M Averell, 40Ardith E Averette, 50Brandon Y Averette, 49Brenda H Averett, 75Brent W Averett, 74

Claudia Averbuj Phones & Addresses

  • 13125 Sunset Point Way, San Diego, CA 92130 (858) 259-9271
  • 4110 Via Candidiz, San Diego, CA 92130 (858) 259-9271
  • 7655 Palmilla Dr, San Diego, CA 92122 (858) 623-0106

Work

Company: Vertex pharmaceuticals - San Diego, CA 2010 Position: Research scientist

Education

School / High School: University of California San Diego- San Diego, CA Apr 2007

Skills

Medicinal Chemistry • Drug Discovery • Organic Synthesis • Chemistry • Drug Design • Pharmaceutical Industry • Mass Spectrometry • Organometallic Chemistry • Nmr • Organic Chemistry • Hplc • Biotechnology • Protein Chemistry • Life Sciences • Chromatography • Lc Ms • Drug Development • Purification • Analytical Chemistry • Assay Development • Pharmacology • Nuclear Magnetic Resonance • Lead Change • Catalysis • Lifesciences • Adme • Heterocyclic Chemistry • High Throughput Screening • Parallel Synthesis • Synthetic Organic Chemistry

Languages

English • Spanish • Hebrew

Emails

c***[email protected]

Industries

Pharmaceuticals

Resumes

Resumes

Claudia Averbuj Photo 1

Senior Scientist

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Location:
San Diego, CA
Industry:
Pharmaceuticals
Work:
Ardelyx, Inc.
Senior Scientist
Dart Neuroscience Llc Mar 2013 - Feb 2018
Research Scientist Ii
Vertex Pharmaceuticals Oct 2010 - Jun 2012
Medicinal Chemist - Contract Research Scientist
Exelixis Mar 2007 - Mar 2010
Senior Scientist
Senomyx Jan 2005 - Mar 2007
Senior Scientist
Education:
Scripps Research 1999 - 2001
Technion - Israel Institute of Technology Jul 1998
Technion - Israel Institute of Technology 1994 - 1998
Doctorates, Doctor of Philosophy, Chemistry
Skills:
Medicinal Chemistry
Drug Discovery
Organic Synthesis
Chemistry
Drug Design
Pharmaceutical Industry
Mass Spectrometry
Organometallic Chemistry
Nmr
Organic Chemistry
Hplc
Biotechnology
Protein Chemistry
Life Sciences
Chromatography
Lc Ms
Drug Development
Purification
Analytical Chemistry
Assay Development
Pharmacology
Nuclear Magnetic Resonance
Lead Change
Catalysis
Lifesciences
Adme
Heterocyclic Chemistry
High Throughput Screening
Parallel Synthesis
Synthetic Organic Chemistry
Languages:
English
Spanish
Hebrew
Claudia Averbuj Photo 2

Claudia Averbuj San Diego, CA

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Work:
Vertex Pharmaceuticals
San Diego, CA
2010 to 2012
Research Scientist
Exelixis, Inc
San Diego, CA
2007 to 2010
Research Scientist II
Senomyx Inc
San Diego, CA
2005 to 2007
Sr. Research Scientist
Arena Pharmaceuticals

Dec 2003 to Dec 2004
Sr. Research Scientist
Arena Pharmaceuticals
San Diego, CA
2001 to 2004
Sr. Research Scientist
Arena Pharmaceuticals

Sep 2001 to Dec 2003
Research Scientist
The Scripps Research Institute
La Jolla, CA
1999 to 2001
Post-Doctoral Research Associate
Claudia Averbuj Photo 3

Claudia L . Averbuj

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Publications

Us Patents

Process For The Production Of Stereoregular Polymers And Elastomers Of Alpha-Olefins And Certain Novel Catalysts Therefor

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US Patent:
6653413, Nov 25, 2003
Filed:
Jan 27, 2000
Appl. No.:
09/492033
Inventors:
Moris Eisen - Tyvon, IL
Victoria Volkis - Haifa, IL
Michal Shmulinson - Ramat Almogi Haifa, IL
Claudia Averbuj - San Diego CA
Edith Tish - Ashkelon, IL
Assignee:
Technion Research and Development Foundation Ltd. - Haifa
International Classification:
C08F 400
US Classification:
526 73, 526161, 526172, 526351, 502117, 502155
Abstract:
A process for the polymerization of one or more alpha-olefins having at least 3 carbon atoms, which comprises contacting the monomer or monomers in a polar or non-polar solvent under polymerization conditions with a homogeneous catalyst system including (a) a cationic form of a racemic mixture of a chiral octahedral transition metal complex or of a non chiral octahedral transition metal complex, comprising 1, 2 or 3 bidentate chelating ligands and no cyclopentadienyl ligands and having C , C , or C symmetry; and (b) an anion of a Lewis acid or a BrÃnsted acid; and adjusting the pressure so as to obtain either a highly stereoregular polymer or copolymer or an elastomer.

Bis-Aromatic Amides And Their Uses As Sweet Flavor Modifiers, Tastants, And Taste Enhancers

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US Patent:
7842324, Nov 30, 2010
Filed:
Jun 15, 2006
Appl. No.:
11/455314
Inventors:
Catherine Tachdjian - San Diego CA, US
Andrew P. Patron - San Marcos CA, US
Farid Bakir - San Diego CA, US
Claudia Averbuj - San Diego CA, US
Chad Priest - Encinitas CA, US
Qing Chen - San Diego CA, US
Vincent Darmohusodo - San Diego CA, US
Rachel D. A. Kimmich - Carlsbad CA, US
Xiao-Qing Tang - San Diego CA, US
Rhondi Shigemura - Encinitas CA, US
Assignee:
Senomyx, Inc. - La Jolla CA
International Classification:
A23L 1/236
US Classification:
426548, 514 43, 514 79
Abstract:
The inventions disclosed herein relate to man-made bi-aromatic amide compounds that, when contacted with comestible food or drinks or pharmaceutical compositions at concentrations preferably on the order of about 100 ppm or lower, serve as sweet taste modifiers, sweet flavoring agents, or sweet flavor enhancers, for use in foods, beverages, and other comestible products, or orally administered medicinal products or compositions, optionally in the presence of or in mixtures with conventional flavoring agents such as known natural saccharide sweeteners and previously known artificial sweeteners.

Process For The Production Of Stereoregular Polymers And Elastomers Of Alpha-Olefins And Certain Novel Catalysts Therefor

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US Patent:
20010029232, Oct 11, 2001
Filed:
May 31, 2001
Appl. No.:
09/870022
Inventors:
Moris Eisen - Tyvon, IL
Victoria Volkis - Haifa, IL
Michal Shmulinson - Ramat Almogi Haifa, IL
Claudia Averbuj - San Diego CA, US
Edith Tish - Ashkelon, IL
International Classification:
B01J031/00
B01J037/00
C08F004/02
C08F004/60
US Classification:
502/103000, 502/102000, 502/117000, 502/158000, 502/167000
Abstract:
A process for the polymerization of one or more alpha-olefins having at least 3 carbon atoms, which comprises contacting the monomer or monomers in a polar or non-polar solvent under polymerization conditions with a homogeneous catalyst system including (a) a cationic form of a racemic mixture of a chiral octahedral transition metal complex or of a non chiral octahedral transition metal complex, comprising 1, 2 or 3 bidentate chelating ligands and no cyclopentadienyl ligands and having C, C, or Csymmetry; and (b) an anion of a Lewis acid or a Brönsted acid; and adjusting the pressure so as to obtain either a highly stereoregular polymer or copolymer or an elastomer.

5-Substituted 2H-Pyrazone-3-Carbixylic Acid Derivatives As Antilipolytic Agents For The Treatment Of Metabolic-Related Disorders Such As Dyslipidemia

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US Patent:
20060167270, Jul 27, 2006
Filed:
Oct 9, 2003
Appl. No.:
10/530902
Inventors:
Graeme Semple - San Diego CA, US
Claudia Averbuj - San Diego CA, US
Philip Skinner - San Diego CA, US
Tawfik Gharbaoui - Escondido CA, US
Young-Jun Shin - San Diego CA, US
Assignee:
Arena Pharmaceuticals Inc. - San Diego CA
International Classification:
C07D 231/08
US Classification:
548364100, 548369400
Abstract:
The present invention relates to certain pyrazole carboxylic acid derivatives of Formula (Ia), and pharmaceutically acceptable salts thereof, as antilipolytic agents and against for the receptor RUP25, wherein: Ris H, halogen, Calkyl or Chaloalkyl; and Ris Ccycloalkyl, Calkyl, Chaloalkyl, Ccycloalkyl-C-alkylene, aryl-C-alkylene or heteroaryl-C-alkylene, wherein said aryl-C-alkylene and heteroaryl-C-alkylene can be optionally substituted 1 to 5 substituents selected from the substituents listed in the claims. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, insulin resistance, type 2 diabetes, Syndrome-X and the like. In addition, the present invention also provides for pharmaceutical compositions in combination with other active agents, for example, those agents belonging to the class of α-glucosidase inhibitors, aldose reductase inhibitors, biguanides, HMG-CoA reductase inhibitors, squalene synthesis inhibitors, fibrates, LDL catabolism enhancers, angiotensin converting enzyme (ACE) inhibitors, insulin secretion enhancers, thiazolidinedione and the like.

5-Substituted 2H-Pyrazole-3-Carboxylic Acid Derivatives As Agonists For The Acid Receptor Rup25 For The Treatment Of Dyslipidemia And Related Diseases

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US Patent:
20070032537, Feb 8, 2007
Filed:
Jun 10, 2004
Appl. No.:
10/560332
Inventors:
Graeme Semple - San Diego CA, US
Tawfik Gharbaoui - San Diego CA, US
Young-Jun Shin - San Diego CA, US
Marc Decaire - San Diego CA, US
Claudia Averbuj - San Diego CA, US
Philip Skinner - San Diego CA, US
Assignee:
Arena Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31/4152
C07D 231/02
US Classification:
514406000, 548374100
Abstract:
The present invention relates to certain pyrazole carboxylic acid and ester derivatives, and pharmaceutically acceptable salts thereof, which exhibit useful pharmaceutical properties, for example as agonists for the RUP25 receptor. (I) Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the prophylaxis or treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, insulin resistance, type 2 diabetes, Syndrome-X and the like. In addition, the present invention also provides for the use of the compounds of the invention in combination with other active agents such as those belonging to the class of α-glucosidase inhibitors, aldose reductase inhibitors, biguanides, HMG-CoA reductase inhibitors, squalene synthesis inhibitors, fibrates, LDL catabolism enhancers, angiotensin converting enzyme (ACE) inhibitors, insulin secretion enhancers and the like the substituents are defined in claim

Process For Preparing Substituted Phenylpyrazole Ureas

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US Patent:
20080194836, Aug 14, 2008
Filed:
Jan 25, 2006
Appl. No.:
11/883043
Inventors:
Tawfik Gharbaoui - Escondido, CA
Claudia Averbuj - San Diego CA, US
Marlony Carlos - Santee CA, US
Edward A. Lally - La Jolla CA, US
Dipanjan Sengupta - San Diego CA, US
John Robert Fritch - Romona CA, US
International Classification:
C07D 231/10
US Classification:
5483751
Abstract:
The present invention is directed to processes for the preparation of substituted phenylpyrazole ureas of Formula (I) that are useful as 5-HTserotonin receptor modulators for the treatment of disease.

Lxr Modulators

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US Patent:
20160289222, Oct 6, 2016
Filed:
Mar 14, 2014
Appl. No.:
14/774839
Inventors:
- Princeton NJ, US
- South San Francisco CA, US
Raju Mohan - Encinitas CA, US
Brett B. Busch - San Diego CA, US
Claudia Averbuj - San Diego CA, US
Meriah Valente - Pennington NJ, US
Nicholas Wurtz - Pennington NJ, US
Prasanna Savanor Maddu Rao - Karnataka, IN
Jeevanprakash Shetty - Karnataka, IN
Alla Venu - Karnataka, IN
Assignee:
BRISTOL-MYERS SQUIBB COMPANY - Princeton NJ
EXELIXIS PATENT COMPANY LLC - South San Francisco CA
International Classification:
C07D 413/14
C07D 405/14
C07D 413/10
C07D 403/10
Abstract:
The present invention provides compounds of Formula I and Formula II: or pharmaceutically acceptable salts or solvates thereof, as modulators of liver X receptors (LXRs), and compositions comprising any of such novel compounds and methods of use thereof. These compounds are useful as medicaments for treatment and/or prophylaxis for diseases or conditions related to activity of LXRs.
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Claudia L Averbuj from San Diego, CA, age ~58 Get Report