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Clague P Hodgson

from Omaha, NE
Age ~78
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Also known as:
Clague Dr Hodgson, Clague Kristi Hodgson, Claque P Hodgson, Claue Hodgson, Corrin Hodgson, Clague Hodgeson, Hodgson Clague, E Hodson, Pitman Hodgson Clague
Phone and address:
101 54Th St, Omaha, NE 68132
(402) 553-4607
Related to:
Riley C Hodgson, 47Kristi K Hodgson, 69Corrin Hodgson, 37
Connected to:
Angelene Hodgson, 38Angus M Hodgson, 72Barry Hodgson, 81Becky S Hodgson, 64Blake S Hodgson, 41Brenton Hodgson, 55Cabot L Hodgson, 60Carrie R Hodgson, 65Clayton W Hodgson, 51Dawnette L Hodgson, 58

Clague Hodgson Phones & Addresses

  • 101 54Th St, Omaha, NE 68132 (402) 553-4607
  • 201 54Th St, Omaha, NE 68132
  • Palos Verdes Estates, CA
  • Lincoln, NE
  • Wooster, OH
  • 101 S 54Th St, Omaha, NE 68132

Work

Company: Nature technology corporation Mar 1999 Position: President and chief executive officer at nature technology corp

Education

School / High School: Baylor College of Medicine 2018 to 2022

Skills

Biotechnology • Biopharmaceuticals • Vaccines • Genetics • Dna • Cell • Technology Transfer • Patents • Life Sciences • Molecular Biology • Lifesciences • Management • Biochemistry • Drug Discovery • Start Ups • Cell Biology • Protein Chemistry • Virology • Technical Writing • Aviation • Immunology • Commercialization • Genomics • Clinical Development • Gmp • Laboratory • Cancer • Gene Therapeutics • Therapists • Drug Development • Protein Purification • Microbiology • Infectious Diseases • Corporate Management • Pcr • Purification • Bioinformatics • Startups • Brewing • Vector Design • Cell Culture • Pharmaceutical Industry • Research • Polymerase Chain Reaction • R&D • Science • Clinical Trials

Interests

Bioprocessing • Genetically Targeted Medicines • Aviation • Plasmids • Gemology • Dna Vaccines • Enology • Instrument Rated • Gia • Biologics • Brewing

Industries

Biotechnology

Resumes

Resumes

Clague Hodgson Photo 1

President And Chief Executive Officer At Nature Technology Corp

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Location:
4701 Innovation Dr, Lincoln, NE 68521
Industry:
Biotechnology
Work:
Nature Technology Corporation
President and Chief Executive Officer at Nature Technology Corp
Creighton University School of Medicine Jul 1991 - Feb 1999
Associate Professor of Biomedical Sciences
The Ohio State University Mar 1985 - May 1991
Assistant Professor
Mayo Clinic 1978 - 1983
Predoctoral Fellow
Education:
Baylor College of Medicine 2018 - 2022
Baylor College of Medicine 1983 - 1985
University of Minnesota 1978 - 1983
Doctorates, Doctor of Philosophy, Biology Mayo Clinic School of Health Sciences 1978 - 1983
Doctorates, Doctor of Philosophy, Biology University of Minnesota 1975 - 1976
Bachelors, Bachelor of Science, Microbiology
Skills:
Biotechnology
Biopharmaceuticals
Vaccines
Genetics
Dna
Cell
Technology Transfer
Patents
Life Sciences
Molecular Biology
Lifesciences
Management
Biochemistry
Drug Discovery
Start Ups
Cell Biology
Protein Chemistry
Virology
Technical Writing
Aviation
Immunology
Commercialization
Genomics
Clinical Development
Gmp
Laboratory
Cancer
Gene Therapeutics
Therapists
Drug Development
Protein Purification
Microbiology
Infectious Diseases
Corporate Management
Pcr
Purification
Bioinformatics
Startups
Brewing
Vector Design
Cell Culture
Pharmaceutical Industry
Research
Polymerase Chain Reaction
R&D
Science
Clinical Trials
Interests:
Bioprocessing
Genetically Targeted Medicines
Aviation
Plasmids
Gemology
Dna Vaccines
Enology
Instrument Rated
Gia
Biologics
Brewing

Business Records

Name / Title
Company / Classification
Phones & Addresses
4701 Innovation Dr #103, Lincoln, NE 68521
Clague P. Hodgson
Principal
Bois Brule, LLC
Business Services at Non-Commercial Site
101 S 54 St, Omaha, NE 68132
Clague Hodgson
President/Owner, CTO
Nature Technology Corporation
Biotechnology · Biotechnology and Gene Therapy Research & Development · Laboratory Apparatus and Furniture · Other Technical Consulting Svcs · Pharmaceutical Preparations · Commercial Physical Research
4701 Innovation Dr SUITE PB-103, Lincoln, NE 68521
(402) 472-6530, (402) 323-6289, (888) 949-2264, (402) 472-4200

Publications

Us Patents

Self-Assembling Genes, Vectors And Uses Thereof

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US Patent:
6410220, Jun 25, 2002
Filed:
Aug 26, 1999
Appl. No.:
09/380190
Inventors:
Clague P. Hodgson - Lincoln NE
Mary Ann Zink - Lincoln NE
Guoping Xu - Lincoln NE
Assignee:
Nature Technology Corp - Omaha NE
International Classification:
C12Q 100
US Classification:
435 4, 435 6, 4353201, 536 231, 536 241
Abstract:
The invention relates to a method for directing the self-assembly of a gene or gene assembly having three and preferably six or more fragments in a directionally and spatially ordered fashion to produce a gene, gene vector or large nucleic acid molecule. The method can be used to create libraries, such as combinatorial libraries. In another embodiment of the invention a vector is described for the incorporation and screeming of endogenous mouse promoter elements for the identification of cell-specific promoters.

Chimeric Viral Packaging Signal Without Gag Gene Sequences

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US Patent:
6573091, Jun 3, 2003
Filed:
Sep 18, 2000
Appl. No.:
09/554572
Inventors:
Clague Hodgson - Lincoln NE
Mary Ann Zink - Lincoln NE
Guoping Xu - Lincoln NE
Assignee:
Nature Technology Corporation - Lincoln NE
International Classification:
C12N 1500
US Classification:
4353201, 4241851, 4241871, 4241991, 435 691, 435456, 514 44, 536 231, 536 234, 536 2372
Abstract:
A chimeric viral packaging signal is described for the transmission of genetic materials via retrovirus. The packaging signal contains an essential packaging nucleic acid sequence and a non-essential nucleic acid sequence. The packaging signal lacks gag gene sequences, and has approximately one order of magnitude greater infectivity than retrovirus-derived packaging signals without gag gene sequences. The packaging signal of the invention can be used to transmit genetic material for gene therapy, cell therapy, or other biotechnological applications.

Vectors For Gene-Self-Assembly

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US Patent:
20020025561, Feb 28, 2002
Filed:
Apr 17, 2001
Appl. No.:
09/836737
Inventors:
Clague Hodgson - Omaha NE, US
International Classification:
C12P019/34
C12N015/86
G06F019/00
G01N033/48
G01N033/50
US Classification:
435/091100, 435/320100, 702/020000
Abstract:
The present invention provides novel vectors and methods for assembling complex DNA molecules starting with a plurality of input gene sequences. The input gene sequences (which overlap with each other by a defined number of bases) are cloned into a vector at a unique restriction site that is flanked on each side by class IIS restriction endonuclease sites. When the clones are digested with the class IIS restriction enzyme, the inserts are released from the vector with a defined number of bases removed from either the 5′ or 3′ termini, corresponding to the overlap sequences. The overlap sequences, which are unique, non-palindromic sequence strings, permit the fragments to self-assemble. When the fragments are ligated, a seamless, unambiguous linear array fragments is created. The invention can be used for assembling synthetic genes, constructs, vectors and chromosomes.

Vectors For Gene Transfer

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US Patent:
20030190753, Oct 9, 2003
Filed:
Aug 21, 2001
Appl. No.:
09/934113
Inventors:
Clague Hodgson - Omaha NE, US
Assignee:
Nature Technology Corporation
International Classification:
C12N015/86
C12N007/00
US Classification:
435/456000, 435/235100, 435/320100
Abstract:
Improved recombinant retrotransposon vectors for gene transfer are disclosed. The synthetic vectors are truncated so as to reduce or altogether eliminate homologous recombination with retroviral helper sequences found in helper cells used to propagate the vectors, making them safer for use in humans and providing more space for therapeutic genes. The vectors transmit foreign DNA efficiently, are stable, enable abundant RNA expression from the retrotransposon transcriptional promoter, and through their diversity permit many useful applications in therapeutics and transgenics. Methods are described for rescuing tissue-specifics promoters obtaining expression in primary cells, mapping the genome and other techniques of therapeutic and transgenic utility.

Rna Transfection Of Sperm Cells

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US Patent:
20040031070, Feb 12, 2004
Filed:
Oct 15, 2001
Appl. No.:
09/977179
Inventors:
Corrado Spadafora - Rome, IT
Clague Hodgson - Omaha NE, US
Rodolfo Lorenzini - Rome, IT
International Classification:
A01K067/027
C12N015/86
US Classification:
800/021000, 435/456000
Abstract:
A method is described for transferring expressible foreign genes into multi-cellular organisms by means of RNA uptake by sperm cells, followed by endogenous reverse transcription of RNA into cDNA. cDNA molecules are transferred to embryos through fertilization, and are transmitted to born animals and their progeny. The cDNA sequences are mosaically distributed in the cells and tissue of the organisms, and are preferentially expressed in target tissues.

Strains Of E. Coli For Plasmid Dna Production

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US Patent:
20070249042, Oct 25, 2007
Filed:
Aug 15, 2005
Appl. No.:
11/573756
Inventors:
James Williams - Lincoln NE, US
Clague Hodgson - Omaha NE, US
International Classification:
C12N 15/74
C12N 1/21
US Classification:
435320100
Abstract:
A general method and strains of bacteria are described, by means of which it is possible to dramatically purify plasmid DNA with respect to genomic DNA, and RNA. In one preferred embodiment, lysis and nuclease removal of host nucleic acids is an integral component of the fermentation/harvest process, and as such, achieves increased yield and purity with simplified down-stream purification and reduced waste streams, thus reducing production costs.

E. Coli Plasmid Dna Production

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US Patent:
20100184157, Jul 22, 2010
Filed:
May 22, 2008
Appl. No.:
12/601504
Inventors:
James A. Williams - Lincoln NE, US
Clague P. Hodgson - Omaha NE, US
Aaron E. Carnes - Lincoln NE, US
Assignee:
NATURE TECHNOLOGY CORPORATION - Lincoln NE
International Classification:
C12N 15/64
C12N 1/21
US Classification:
435 914, 4352523, 43525233
Abstract:
General methods and strains of bacteria are described, that dramatically simplify and streamline plasmid DNA production. In one preferred embodiment, endolysin mediated plasmid extraction combined with flocculation mediated removal of cell debris and host nucleic acids achieves increased yield and purity with simplified downstream purification and reduced waste streams, thus reducing production costs.

Method Of Gene Transfer Using Retrotransposons

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US Patent:
53546741, Oct 11, 1994
Filed:
Oct 29, 1992
Appl. No.:
7/968259
Inventors:
Clague P. Hodgson - Wooster OH
Assignee:
Creighton University - Omaha NE
International Classification:
C12N 1500
C12N 500
C12N 700
US Classification:
4351723
Abstract:
A process for the transfer and/or expression of any gene into cells, organisms or species is disclosed. The process involves isolating the gene, introducing the gene into a vector comprised of at least one retrotransposon genetic element to provide a hybrid gene. The hybrid gene is introduced into a donor cell capable of packaging and transmitting the retrotransposon to other cells, organisms or species. The hybrid gene is transferred to a recipient cell wherein the hybrid gene replicates by reverse transcription and is inserted into the recipient cell's genome. The gene is preferably expressed as RNA and/or protein, giving the phenotype of the gene.

Isbn (Books And Publications)

Retro-Vectors for Human Gene Therapy

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Author

Clague P. Hodgson

ISBN #

3540606858

Control profile
Clague P Hodgson from Omaha, NE, age ~78 Get Report