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Christopher L Schardl

from Lexington, KY
Age ~67
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Also known as:
Christopher Lewis Schardl, Christopher Lew Schardl, Chris L Schardl, Christopher L Schard, Christoph L Schardi, Christopher L, Christoph L
Phone and address:
113 Shawnee Pl, Lexington, KY 40503
(859) 277-5944
Related to:
Tao Schardl, 37Anisa H Schardl, 39Chen Kuey, 70Anisa Schardl, 67
Connected to:
Donovan D Schardt, 80Gayle A Schardt, 79Jamie I Schardt, 43Linsey Schardt, 41Melissa A Schardt, 47Michael Schardt, 71Peter C Schardt, 86Ralph H Schardt, 104Stefan W Schardt, 60Todd D Schardt, 50

Christopher Schardl Phones & Addresses

  • 113 Shawnee Pl, Lexington, KY 40503 (859) 277-5944
  • 158 Wabash Dr, Lexington, KY 40503 (859) 253-9950
  • Bethel, NY
  • Fremont Center, NY
  • Swan Lake, NY
  • Long Eddy, NY
  • 113 Shawnee Pl, Lexington, KY 40503 (859) 466-6692

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Emails

a***[email protected]

Resumes

Resumes

Christopher Schardl Photo 1

Professor

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Location:
Lexington, KY
Industry:
Higher Education
Work:
University of Kentucky since 1985
Professor
Education:
University of California, Davis 1978 - 1983
Doctor of Philosophy (Ph.D.), Biochemistry Cornell University 1974 - 1978
Bachelor of Science (B.S.), Biochemistry
Skills:
Phylogenetics
Molecular Genetics
Molecular Biology
Bioinformatics
Biochemistry
Functional Genomics
Christopher Schardl Photo 2

Professor

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Location:
Lexington, KY
Industry:
Higher Education
Work:
University of Kentucky
Professor

Publications

Us Patents

Loline Alkaloid Gene Clusters Of The Fungal Endophyte Neotyphodium Uncinatum

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US Patent:
7183098, Feb 27, 2007
Filed:
Jun 24, 2003
Appl. No.:
10/601700
Inventors:
Christopher L. Schardl - Lexington KY, US
Heather H. Wilkinson - College Station TX, US
Martin J. Spiering - Lexington KY, US
Assignee:
University of Kentucky Research Foundation - Lexington KY
International Classification:
C12P 17/14
C07H 21/04
A63B 69/36
US Classification:
4352523, 435120, 4353201, 43525233, 4352528, 43525411, 536 232
Abstract:
Loline alkaloids (LA), which are 1-aminopyrrolizidines with an oxygen bridge, are produced by (anamorph=) species, endophytes of grasses. LA are insecticidal, thus helping protect host plants from insect herbivory. Suppression subtractive hybridization PCR was used to isolate transcripts up-regulated during loline alkaloid production in cultures of. Subtracted cDNAs were cloned, and a λ-phage cDNA library from an LA-expressing culture was screened with subtracted cDNA. In BLAST searches, several cDNAs identified had sequence similarities to aspartate kinases, and another with O-acetylhomoserine-(thiol)lyase. Differential expression of these two genes in LA-producing cultures of was confirmed, and in a survey of 23 isolates from 21 and species these two genes strictly correlated with LA production. Two nucleic acid molecules encoding two loline alkaloid gene clusters have been identified.

Endophyte Ergot Alkaloid Synthetic Compounds, Compounds Which Encode Therefor And Related Methods

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US Patent:
6335188, Jan 1, 2002
Filed:
Mar 3, 2000
Appl. No.:
09/518657
Inventors:
Christopher L. Schardl - Lexington KY
Jinghung Wang - Lexington KY
Assignee:
University of Kentucky Research Foundation - Lexington KY
International Classification:
C12P 2106
US Classification:
435193, 435 691, 435183, 4352523, 4352541, 43525411, 4353201, 435410, 435419, 536 232, 536 236, 536 237, 536 2374
Abstract:
The present invention provides, inter alia, dmaW nucleic acid sequences and the proteins for which they encode. Also provided are methods for the utilization of knockout mutants of the sequences which are useful for engineering ergot alkaloid-deficient fungal symbionts (endophytes) of plants. Other methods and materials related to these sequences are also provided.
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Christopher L Schardl from Lexington, KY, age ~67 Get Report