US Patent:
20110033501, Feb 10, 2011
Inventors:
Roy Curtiss iii - Paradise Valley AZ, US
Melha Mellata - Tempe AZ, US
Bereket Zekarias - Mesa AZ, US
Zhaoxing Shi - Tempe AZ, US
Christine Branger - Phoenix AZ, US
Kenneth Roland - Mesa AZ, US
Assignee:
The Arizona Board of Regents for and on behalf of Arizona State University - Tempe AZ
International Classification:
A61K 39/112
C12N 1/21
A61P 37/04
Abstract:
The present invention relates to a recombinant bacterium that is capable of eliciting an immune response against at least two enteric pathogens, without substantially inducing an immune response specific to the serotype of the bacterium. The invention also relates to methods of making such a bacterium and vaccines and methods of using such a bacterium.