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Christian Stehlik

from Los Angeles, CA
Age ~56
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Also known as:
Christain Stehlik, Christian Stehuk
Phone and address:
6610 Maryland Dr, Los Angeles, CA 90048
Related to:
Christain Stehlik, 56
Connected to:
Debra Stehlik, 55Milan S Stehlik, 51Noreene C Stehlik, 69Angelica B Stehling, 60Donna M Stehlin, 63Edward J Stehling, 57James L Stehlin, 64John A Stehlin, 96Mark L Stehling, 47Sarah C Stehlin, 43

Christian Stehlik Phones & Addresses

  • 6610 Maryland Dr, Los Angeles, CA 90048
  • Chicago, IL
  • Oak Park, IL
  • Morgantown, WV
  • La Jolla, CA
  • San Diego, CA

Business Records

Name / Title
Company / Classification
Phones & Addresses
Christian Stehlik
Associate Professor
Virginia West University
General Hospital
Wv Hlth Scncs Ctr, Morgantown, WV 26506

Publications

Us Patents

Card Domain Containing Polypeptides, Encoding Nucleic Acids, And Methods Of Use

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US Patent:
7196182, Mar 27, 2007
Filed:
May 23, 2001
Appl. No.:
09/864921
Inventors:
John C. Reed - San Diego CA, US
Frederick F. Pio - Vancouver, CA
Adam Godzik - San Diego CA, US
Christian Stehlik - San Diego CA, US
Jason S. Damiano - San Diego CA, US
Sug Hyung Lee - San Diego CA, US
Vasco A. Oliveira - San Diego CA, US
Hideki Hayashi - Nagasaki, JP
Krzysztof Pawlowski - Malmo, SE
Assignee:
The Burnham Institute - La Jolla CA
International Classification:
C07H 21/02
C12Q 1/68
US Classification:
536 231, 435 6
Abstract:
The invention provides caspase recruitment domain (CARD)-containing polypeptides, CARD, NB-ARC, ANGIO-R, LRR and SAM domains therefrom, as well as encoding nucleic acid molecules and specific antibodies. The invention also provides related screening, diagnostic and therapeutic methods.

Card Domain Containing Polypeptides, Encoding Nucleic Acids, And Methods Of Use

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US Patent:
7626001, Dec 1, 2009
Filed:
Mar 26, 2007
Appl. No.:
11/728892
Inventors:
John C. Reed - Rancho Santa Fe CA, US
Frederick F. Pio - Vancouver, CA
Adam Godzik - San Diego CA, US
Christian Stehlik - San Diego CA, US
Jason S. Damiano - La Jolla CA, US
Sug Hyung Lee - San Diego CA, US
Vasco A. Oliveira - San Diego CA, US
Hideki Hayashi - Nagasaki, JP
Kryzysztof Pawlowski - Malmo, SE
Assignee:
Burnham Institute for Medical Research - La Jolla CA
International Classification:
C07K 14/00
US Classification:
530350
Abstract:
The invention provides caspase recruitment domain (CARD)-containing polypeptides, CARD, NB-ARC, ANGIO-R, LRR and SAM domains therefrom, as well as encoding nucleic acid molecules and specific antibodies. The invention also provides related screening, diagnostic and therapeutic methods.

Paad Domain-Containing Polypeptides, Encoding Nucleic Acids, And Methods Of Use

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US Patent:
20030077699, Apr 24, 2003
Filed:
Sep 25, 2001
Appl. No.:
09/965621
Inventors:
John Reed - San Diego CA, US
Adam Godzik - San Diego CA, US
Zhi-Liang Chu - San Diego CA, US
Krzysztof Pawlowski - Malmo, SE
Loredana Fiorentino - San Diego CA, US
Maria Ariza - San Diego CA, US
Christian Stehlik - San Diego CA, US
International Classification:
G01N033/53
C12P021/02
C12N005/06
C07H021/04
C07K014/705
US Classification:
435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:
The invention provides isolated nucleic acid molecules encoding PAAD-domain containing polypeptides and functional fragments thereof, including fragments containing PAAD domains, NB-ARC domains and LRR domains, encoded polypeptides, and antibodies. Also provided are methods of identifying polypeptides and agents that associate with a PAAD-domain containing polypeptide or fragment thereof, or that alter an association of a PAAD domain-containing polypeptides. Further provided are methods of identifying agents that modulate PAAD domain-mediated inhibition of NF B activity, or modulate an activity of an NB-ARC domain of a PAAD domain-containing polypeptide. Also provided are methods of modulating NF B transcriptional activity in a cell, and methods of altering expression of a PAAD domain-containing polypeptide in a cell.

Paad Domain-Containing Polypeptides, Encoding Nucleic Acids, And Methods Of Use

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US Patent:
20040142374, Jul 22, 2004
Filed:
Feb 17, 2004
Appl. No.:
10/781294
Inventors:
John Reed - San Diego CA, US
Adam Godzik - San Diego CA, US
Zhi-Liang Chu - San Diego CA, US
Krzysztof Pawlowski - Malmo, SE
Loredana Fiorentino - San Diego CA, US
Maria Ariza - San Diego CA, US
Christian Stehlik - San Diego CA, US
Assignee:
THE BURNHAM INSTITUTE.
International Classification:
C12Q001/68
C07H021/04
C12N001/18
C07K014/47
US Classification:
435/006000, 435/069100, 435/320100, 435/254200, 530/350000, 536/023500
Abstract:
The invention provides isolated nucleic acid molecules encoding PAAD-domain containing polypeptides and functional fragments thereof, including fragments containing PAAD domains, NB-ARC domains and LRR domains, encoded polypeptides, and antibodies. Also provided are methods of identifying polypeptides and agents that associate with a PAAD-domain containing polypeptide or fragment thereof, or that alter an association of a PAAD domain-containing polypeptides. Further provided are methods of identifying agents that modulate PAAD domain-mediated inhibition of NFkB activity, or modulate an activity of an NB-ARC domain of a PAAD domain-containing polypeptide. Also provided are methods of modulating NFkB transcriptional activity in a cell, and methods of altering expression of a PAAD domain-containing polypeptide in a cell.

Card3X-2 Polypeptides, Encoding Nucleic Acids, And Methods Of Use

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US Patent:
20050037378, Feb 17, 2005
Filed:
Jan 27, 2004
Appl. No.:
10/766682
Inventors:
John Reed - Rancho Santa Fe CA, US
Frederick Pio - British Columbia, CA
Adam Godzik - San Diego CA, US
Christian Stehlik - Morgantown WV, US
Jason Damiano - San Diego CA, US
Sug Lee - Seoul, KR
Vasco Oliveira - San Diego CA, US
Hideki Hayashi - Nagasaki City, JP
Kryzysztof Pawlowski - Malmo, SE
International Classification:
C12Q001/68
C07H021/04
C12N009/64
US Classification:
435006000, 435069100, 435226000, 435320100, 435325000, 536023200
Abstract:
The invention provides a polypeptide corresponding to a newly identified splice variant of the CARD3X gene, termed CARD3X-2. Also provided by the invention is an encoding nucleic acid molecule, as well as a CARD3X-2 specific antibody. The invention further provides related screening, diagnostic and therapeutic methods.

Compositions And Methods For Modulation Of Immune Response

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US Patent:
20200397858, Dec 24, 2020
Filed:
Jun 18, 2019
Appl. No.:
16/444909
Inventors:
- Evanston IL, US
Christian Stehlik - Evanston IL, US
International Classification:
A61K 38/17
Abstract:
Provided herein are compositions and methods for modulation of immune response via PYRIN domain-only proteins POP1 and/or POP3. In particular, POP1 and/or POP3 are inhibited to enhance an immune response (e.g., to treat or prevent infection), or POP1 and/or POP3 are administered or activated to reduce an immune response (e.g., to treat or prevent autoimmune or inflammatory disease).

Compositions And Methods For Modulation Of Immune Response

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US Patent:
20160354437, Dec 8, 2016
Filed:
Feb 13, 2015
Appl. No.:
15/117629
Inventors:
- Evanston IL, US
Christian Stehlik - Evanston IL, US
Assignee:
Northwestern University - Evanston IL
International Classification:
A61K 38/17
Abstract:
Provided herein are compositions and methods for modulation of immune response via PYRIN domain-only proteins POP1 and/or POP3. In particular, POP1 and/or POP3 are inhibited to enhance an immune response (e.g., to treat or prevent infection), or POP1 and/or POP3 are administered or activated to reduce an immune response (e.g., to treat or prevent autoimmune or inflammatory disease).
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Christian Stehlik from Los Angeles, CA, age ~56 Get Report