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Cheryl F Dreyfus

from Short Hills, NJ
Age ~79

Cheryl Dreyfus Phones & Addresses

  • 310 Long Hill Dr, Short Hills, NJ 07078 (973) 912-8387
  • Tenafly, NJ

Publications

Us Patents

Method Of Utilizing Neurotrophins To Manipulate Reproductive Capacity

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US Patent:
7378388, May 27, 2008
Filed:
Oct 5, 2005
Appl. No.:
11/243619
Inventors:
David B. Seifer - Holmdel NJ, US
Robert Shelden - Kendall Park NJ, US
Bo Feng - Edison NJ, US
Cheryl Dreyfus - Short Hills NJ, US
Assignee:
University of Medicine and Dentistry of New Jersey - Somerset NJ
International Classification:
A01N 37/00
A61K 38/00
US Classification:
514 2, 514 7, 514 8, 514 12
Abstract:
Methods and kits are provided for manipulating and predicting the reproductive capacity of a female subject. The presence of endogenous neurotrophins and addition of exogenous neurotrophins, particularly BDNF, NT-4/5, and NGF, increase the reproductive capacity of a female patient by binding to receptors on the oocytes and stimulating maturation of the oocytes. Administration of antagonists act as a contraceptive because the antagonists prevent the neurotrophins from binding to oocyte receptors. Neurotrophins may also be used to stimulate the maturation of oocyte in vitro.

Method Of Utilizing Neurotrophins To Manipulate Reproductive Capacity

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US Patent:
20030049244, Mar 13, 2003
Filed:
Jul 31, 2002
Appl. No.:
10/209779
Inventors:
David Seifer - Holmdel NJ, US
Robert Shelden - Kendall Park NJ, US
Bo Feng - Edison NJ, US
Cheryl Dreyfus - Short Hills NJ, US
International Classification:
A61K038/43
A61K038/18
US Classification:
424/094100, 514/012000
Abstract:
Methods and kits are provided for manipulating and predicting the reproductive capacity of a female subject. The presence of endogenous neurotrophins and addition of exogenous neurotrophins, particularly BDNF, NT-4/5, and NGF, increase the reproductive capacity of a female patient by binding to receptors on the oocytes and stimulating maturation of the oocytes. Administration of antagonists act as a contraceptive because the antagonists prevent the neurotrophins from binding to oocyte receptors. Neurotrophins may also be used to stimulate the maturation of oocyte in vitro.
Cheryl F Dreyfus from Short Hills, NJ, age ~79 Get Report