Chensheng M Li

6805878, Oct 19, 2004

Dec 14, 2001

10/014785

Chensheng Li - Miami FL
Viet Nguyen - Miami FL

Noven Pharmaceuticals, Inc. - Miami FL

A61F 1300

424449, 424448, 424443

Disclosed is a dermal composition comprising enalapril ethyl ester or another prodrug corresponding to a pharmaceutically active form of an ACE inhibitor in an amount corresponding to a therapeutically effective amount of enalaprilat (or other pharmaceutically active form of enalapri) or pharmaceutically active form of the ACE inhibitor in admixture with a pharmaceutically acceptable carrier. In a preferred embodiment, the carrier is a pressure-sensitive adhesive matrix comprising a polymer or polymer blend. The dermal composition is applied in a method of substantially increasing the flux of enalaprilat through the skin of a human or an animal by maintaining the dermal composition in contact with the skin.

6905016, Jun 14, 2005

Jan 18, 2002

10/051220

David P. Kanios - Miami FL, US
Juan A. Mantelle - Miami FL, US
Paul Johnson - Miami FL, US
Chensheng Li - Miami FL, US

Noven Pharmaceuticals, Inc. - Miami FL

B65D081/26

206204, 206438, 206439

A device and method for stabilizing a drug, particularly a chiral drug or the active enantiomer(s) thereof, in a carrier composition of a transdermal delivery system prior to the systems use by providing a product packaging system to prevent or control degradation reactions that can result from certain packaging materials and moisture contamination, while at the same time providing a child-resistant wrapping for the transdermal system.

8186506, May 29, 2012

May 16, 2005

11/130325

David P. Kanios - Miami FL, US
Juan A. Mantelle - Miami FL, US
Paul Johnson - Miami FL, US
Chensheng Li - Miami FL, US

Noven Pharmaceuticals, Inc. - Miami FL

B65D 81/26

206204, 206484, 2064841, 220 2383

A device and method for stabilizing a drug, particularly a chiral drug or the active enantiomer(s) thereof, in a carrier composition of a transdermal delivery system prior to the systems use by providing a product packaging system to prevent or control degradation reactions that can result from certain packaging materials and moisture contamination, while at the same time providing a child-resistant wrapping for the transdermal system.

20050100589, May 12, 2005

Oct 15, 2004

10/965226

Chensheng Li - Miami FL, US
Viet Nguyen - Miami FL, US

A61K031/401
A61K009/70

424449000, 514423000

Disclosed is a dermal composition comprising enalapril ethyl ester or another prodrug corresponding to a pharmaceutically active form of an ACE inhibitor in an amount corresponding to a therapeutically effective amount of enalaprilat (or other pharmaceutically active form of enalapri) or pharmaceutically active form of the ACE inhibitor in admixture with a pharmaceutically acceptable carrier. In a preferred embodiment, the carrier is a pressure-sensitive adhesive matrix comprising a polymer or polymer blend. The dermal composition is applied in a method of substantially increasing the flux of enalaprilat through the skin of a human or an animal by maintaining the dermal composition in contact with the skin.

60249749, Feb 15, 2000

May 27, 1997

8/863563

Chensheng Li - Miami FL

Noven Pharmaceuticals, Inc. - Miami FL

A61F 1302

424448

A transdermal composition and related method are described. Specifically, the transdermal composition is substantially free of gestodene or substantially free of isopropyl myristate and substantially free of lower alkanols and comprises: (a) a therapeutically effective amount of a pharmacologically active drug which is subject to acid catalyzed degradation; (b) a pharmaceutically acceptable carrier; and (c) a penetration enhancing effective amount of a functional derivative of a fatty acid.