Inventors:
Richard Apodaca - San Diego CA, US
Xiaohu Deng - San Diego CA, US
Jill A. Jablonowski - San Diego CA, US
Neelakandha Mani - San Diego CA, US
Chennagiri R. Pandit - San Diego CA, US
Wei Xiao - San Diego CA, US
Assignee:
Ortho-McNeil Pharmaceutical, Inc. - Raritan NJ
International Classification:
A61K 31/54
A61K 31/445
C07D 239/02
C07D 401/02
US Classification:
514316, 514318, 514326, 514408, 514422, 546186, 546229, 548524, 548566
Abstract:
Substituted phenylalkynes of formula (I), compositions containing them, and methods of making and using them to treat histamine-mediated conditions.