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Celine M Bonnefous

from San Diego, CA
Age ~51

Celine Bonnefous Phones & Addresses

  • 4425 Via Sepulveda, San Diego, CA 92122 (858) 638-9255
  • 3937 Nobel Dr, San Diego, CA 92122
  • Houston, TX
  • La Jolla, CA
  • 4425 Via Sepulveda UNIT 3, San Diego, CA 92122

Work

Company: Wilson sonsini goodrich & rosati Nov 2013 Position: Patent agent

Education

Degree: Masters School / High School: University of Houston 1995 to 1999 Specialities: Chemistry

Skills

Drug Discovery • Assay Development • Lifesciences • Pharmaceutical Industry • Molecular Biology • Cell Culture • Clinical Development • Oncology • Hplc • Organic Synthesis

Languages

French

Industries

Pharmaceuticals

Resumes

Resumes

Celine Bonnefous Photo 1

Patent Agent

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Location:
San Diego, CA
Industry:
Pharmaceuticals
Work:
Wilson Sonsini Goodrich & Rosati
Patent Agent

Aragon Pharmaceutical Jul 2009 - Sep 2013
Medicinal Chemistry Scientist

Kalypsys May 2005 - May 2009
Scientist

Merck Sep 1999 - Jun 2005
Research Associate
Education:
University of Houston 1995 - 1999
Masters, Chemistry
Ecole Supérieure De Chimie Organique Et Minérale 1991 - 1996
Bachelors, Bachelor of Science, Chemistry
Skills:
Drug Discovery
Assay Development
Lifesciences
Pharmaceutical Industry
Molecular Biology
Cell Culture
Clinical Development
Oncology
Hplc
Organic Synthesis
Languages:
French

Publications

Us Patents

Aza-Cyclic Compounds As Modulators Of Acetylcholine Receptors

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US Patent:
7408067, Aug 5, 2008
Filed:
Jul 29, 2002
Appl. No.:
10/500517
Inventors:
Peter Charles Astles - Basingstoke, GB
Stephen Richard Baker - Basingstoke, GB
Celine Bonnefous - San Diego CA, US
Jean Michel Vernier - San Diego CA, US
Martine Keenan - Basingstoke, GB
Adam Jan Sanderson - Basingstoke, GB
Assignee:
Merck + Co., Inc. - Rahway NJ
International Classification:
C07D 211/22
C07D 401/00
US Classification:
546196, 546197, 546198, 546199, 546201, 546192
Abstract:
Compounds comprising an aza-cyclic portion and an aromatic portion linked via a sulphur atom are disclosed. The compounds disclosed are selective modulators of beta 4 subtype nicotinic acetylcholine receptors and are useful for the treatment of dysfunctions of the central and autonomic nervous systems.

Benzoxazinyl-Amidocyclopentyl-Heterocyclic Modulators Of Chemokine Receptors

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US Patent:
7700591, Apr 20, 2010
Filed:
May 13, 2005
Appl. No.:
11/129512
Inventors:
Stephen D. Goble - Edison NJ, US
Sander G. Mills - Scotch Plains NJ, US
Lihu Yang - Edison NJ, US
Alexander Pasternak - Princeton NJ, US
Celine Bonnefous - San Diego CA, US
Theodore M Kamenecka - Palm Beach Gardens FL, US
Jean-Michel Vernier - Laguna Niguel CA, US
John H. Hutchinson - LaJolla CA, US
Essa Hu - Camarillo CA, US
Steven Govek - San Diego CA, US
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 31/535
C07D 265/12
C07D 498/00
US Classification:
5142295, 544 90
Abstract:
Cyclopentyl compounds linked to a benzoxazinyl group through an amido moiety utilizing the ring nitrogen of the benzoxazine, and further substituted with a heterocyclic moiety, such compounds represented by formula I:.

Estrogen Receptor Modulators And Uses Thereof

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US Patent:
8299112, Oct 30, 2012
Filed:
Sep 15, 2011
Appl. No.:
13/234035
Inventors:
Nicholas D. Smith - San Diego CA, US
Mehmet Kahraman - La Jolla CA, US
Steven P. Govek - San Diego CA, US
Johnny Y. Nagasawa - San Diego CA, US
Andiliy G. Lai - San Diego CA, US
Jackaline D. Julien - Del Mar CA, US
Celine Bonnefous - San Diego CA, US
Assignee:
Aragon Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31/416
C07D 231/56
US Classification:
514406, 5483611
Abstract:
Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Estrogen Receptor Modulators And Uses Thereof

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US Patent:
8455534, Jun 4, 2013
Filed:
Sep 13, 2012
Appl. No.:
13/613467
Inventors:
Nicholas D. Smith - San Diego CA, US
Mehmet Kahraman - La Jolla CA, US
Steven P. Govek - San Diego CA, US
Johnny Y. Nagasawa - San Diego CA, US
Andiliy G. Lai - San Diego CA, US
Jackaline D. Julien - Del Mar CA, US
Celine Bonnefous - San Diego CA, US
Assignee:
Aragon Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31/416
C07D 231/56
US Classification:
514406, 5483611
Abstract:
Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Metabotropic Glutamate Receptor-5 Modulators

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US Patent:
20050065340, Mar 24, 2005
Filed:
Nov 26, 2002
Appl. No.:
10/497452
Inventors:
Jeannie Arruda - San Diego CA, US
Celine Bonnefous - San Diego CA, US
Brian Campbell - San Diego CA, US
Rowena Cube - San Diego CA, US
Benito Munoz - San Diego CA, US
Brian Stearns - San Diego CA, US
Jean-Michel Vernier - San Diego CA, US
Bowei Wang - San Diego CA, US
Xiumin Zhao - San Diego CA, US
International Classification:
C07D471/02
C07D417/02
C07D413/02
C07D043/02
US Classification:
544127000, 546116000, 546117000, 548217000, 548181000, 546272700, 544139000, 544333000, 546198000, 546119000, 548306100
Abstract:
Phenyl compounds substituted at the 1-position with a fused bicyclo moeity formed from a five-membered heterocycle fused to a six-membered carbocycle, to a six-membered aryl, or to a six-membered hetaryl, and further optionally substituted at 2 the 3,4 positions, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, and panic, as well as in the treatment of pain and other diseases.

Multicyclic Sulfonamide Compounds As Inhibitors Of Histone Deacetylase For The Treatment Of Disease

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US Patent:
20070027184, Feb 1, 2007
Filed:
Jul 27, 2006
Appl. No.:
11/496784
Inventors:
James Malecha - San Diego CA, US
Stewart Noble - San Diego CA, US
Brandon Wiley - Philadelphia PA, US
Timothy Hoffman - San Diego CA, US
Celine Bonnefous - San Diego CA, US
Michael Sertic - Euclid OH, US
Paul Wash - San Diego CA, US
Nicholas Smith - San Diego CA, US
Christian Hassig - Mira Mesa CA, US
Shawn Scranton - San Diego CA, US
Joseph Payne - Oceanside CA, US
Jeffery Hager - San Diego CA, US
International Classification:
A61K 31/47
C07D 215/12
C07D 319/14
A61K 31/36
US Classification:
514311000, 514465000, 514452000, 546176000, 549362000, 549454000
Abstract:
Disclosed herein are sulfonamide compounds of Formula VII as described herein. Methods and compositions are disclosed for treating disease states including, but not limited to cancers, autoimmune diseases, tissue damage, central nervous system disorders, neurodegenerative disorders, fibrosis, bone disorders, polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, cardiovascular conditions, and disorders in which angiogenesis play a role in pathogenesis, using the compounds of the invention. In addition, methods of modulating the activity of histone deacetylase (HDAC) are also disclosed.

Bipyridyl Amines And Ethers As Modulators Of Metabotropic Glutamate Receptor-5

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US Patent:
20070027321, Feb 1, 2007
Filed:
Aug 27, 2004
Appl. No.:
10/570068
Inventors:
Theodore Kamenecka - San Diego CA, US
Jean-Michel Vernier - San Diego CA, US
Celine Bonnefous - San Diego CA, US
Steven Govek - San Diego CA, US
John Hutchinson - La Jolla CA, US
International Classification:
A61K 31/4743
C07D 471/02
C07D 401/02
C07D 417/14
US Classification:
546114000, 546264000, 546261000, 546256000
Abstract:
The present invention is directed to novel bipyridyl amine and ether compounds such as those of Formula (I): (I) (where R?1#191, R?2#191, R?3#191, X and Y are as defined herein) which are mGluR5 modulators useful in the treatment or prevention of diseases and conditions in which mGluR5 is involved, including but not limited to psychiatric and mood disorders such as schizophrenia, anxiety, depression, bipolar disorders, and panic, as well as in the treatment of pain, Parkinson's disease, cognitive dysfunction, epilepsy, circadian rhythm and sleep disorders, such as shift-work induced sleep disorder and jet-lag, drug addiction, drug abuse, drug withdrawal, obesity and other diseases. The invention is also directed to pharmaceutical compositions comprising these compounds. This invention further provides a method of treatment of these disorders and conditions by the administration of an effective amount of these novel bipyridyl amine and/or ether compounds and/or compositions containing these compounds.

Alkyne Derivatives As Tracers For Metabotropic Glutamate Receptor Binding

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US Patent:
20070060618, Mar 15, 2007
Filed:
Oct 24, 2003
Appl. No.:
10/532634
Inventors:
Nicholas David Cosford - San Diego CA, US
Terence Hamill - Lansdale PA, US
Theodore Kamenecka - San Diego CA, US
Thomas Seiders - San Diego CA, US
Jeffrey Roppe - Temecula CA, US
Celine Bonnefous - San Diego CA, US
Donald Burns - Harleysville PA, US
Matthew Braun - Scotch Plains NJ, US
Dennis Dean - Cranford NJ, US
Joseph Simeone - Harrington Park NJ, US
Assignee:
MERCK & CO., INC. - RAHWAY NJ
International Classification:
A61K 31/444
A61K 31/4439
A61K 31/426
A61K 51/00
C07D 417/14
US Classification:
514332000, 514342000, 514369000, 546255000, 546256000, 546269700, 548201000
Abstract:
The present invention is directed to isotopically labeled alkyne derivative compounds, particularly C, C, C, F, O, N, S, H, and H labeled compounds. In particular, the present invention is directed to C, C, C, F, O, N, S, H, and H labeled heterocyclic alkynes and methods of their preparation. The present invention further includes a method of use of the C, F, O, or N labeled heterocyclic alkyne compounds as tracers in positron emission tomography (PET) imaging, particularly in the study of metabolic conditions in mammals, specifically conditions modulated by metabotropic glutamate receptors subtype 5 (mGluR5).
Celine M Bonnefous from San Diego, CA, age ~51 Get Report