Inventors:
Buket Grau - Arlington MA, US
David Robert Gale - Cambridge, GB
Sam Anne Musgrave - Cambridge, GB
George McGee Perkins - Cambridge, GB
Mark Jeffrey Edhouse - Levin, NZ
Marc Graham - Somerville MA, US
Christopher Kadamus - Jamaica Plain MA, US
Assignee:
E2 LLC - Morris Plains NJ
International Classification:
A61M 5/00
A61F 2/04
US Classification:
604 8, 604 9, 623 2365, 623 2368
Abstract:
A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having a disc-shaped inlet and a helical flange. The helical flange may be disposed in a contracted position defining a contracted length and a contracted diameter and an extended position defining an extended length and an extended diameter, wherein the extended length is longer than the contracted length and the extended diameter is smaller than the contracted diameter. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its contracted and extended positions. Insertion and removal systems are also provided for use with the pyloric valve.