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Buket E Grau

from Arlington, MA
Age ~51

Buket Grau Phones & Addresses

  • 42 Ashland St, Arlington, MA 02476 (781) 643-3325 (781) 777-4728
  • Cambridge, MA
  • Boston, MA
  • Somerville, MA
  • 42 Ashland St, Arlington, MA 02476 (781) 777-4728

Resumes

Resumes

Buket Grau Photo 1

Buket Grau

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Location:
Greater Boston Area
Industry:
Biotechnology
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Buket Grau

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Publications

Us Patents

Pyloric Valve Devices And Methods

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US Patent:
8142385, Mar 27, 2012
Filed:
Apr 9, 2009
Appl. No.:
12/384890
Inventors:
Buket Grau - Arlington MA, US
David Robert Gale - Cambridge, GB
Sam Anne Musgrave - Cambridge, GB
George McGee Perkins - Cambridge, GB
Mark Jeffrey Edhouse - Levin, NZ
Marc Graham - Somerville MA, US
Christopher Kadamus - Jamaica Plain MA, US
Assignee:
E2 LLC - Morris Plains NJ
International Classification:
A61M 5/00
A61F 2/04
US Classification:
604 8, 604 9, 623 2365, 623 2368
Abstract:
A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having a disc-shaped inlet and a helical flange. The helical flange may be disposed in a contracted position defining a contracted length and a contracted diameter and an extended position defining an extended length and an extended diameter, wherein the extended length is longer than the contracted length and the extended diameter is smaller than the contracted diameter. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its contracted and extended positions. Insertion and removal systems are also provided for use with the pyloric valve.

Pyloric Valve Devices And Methods

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US Patent:
8182442, May 22, 2012
Filed:
Apr 9, 2009
Appl. No.:
12/384889
Inventors:
Buket Grau - Arlington MA, US
David Robert Gale - Cambridge, GB
Sam Anne Musgrave - Cambridge, GB
George McGee Perkins - Cambridge, GB
Mark Jeffrey Edhouse - Levin, NZ
Marc Graham - Somerville MA, US
Christopher Kadamus - Jamaica Plain MA, US
Assignee:
ElectroCore LLC - Morris Plains NJ
International Classification:
A61M 5/00
A61B 17/08
A61F 2/04
US Classification:
604 9, 606153, 623 2365
Abstract:
A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having a plurality of disc-shaped flanges connected in series. The blocking portion may be disposed in a contracted position wherein the plurality of disc-shaped flanges is disposed in a stacked configuration and a resting position wherein the plurality of disc-shaped flanges is disposed in a linear configuration. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its resting and contracted positions. Insertion and removal systems are also provided for use with the pyloric valve.

Pyloric Valve

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US Patent:
8226593, Jul 24, 2012
Filed:
Apr 8, 2009
Appl. No.:
12/420219
Inventors:
Marc Graham - Somerville MA, US
Buket Grau - Arlington MA, US
Assignee:
E2 LLC - Morris Plains NJ
International Classification:
A61M 5/00
A61F 2/04
US Classification:
604 9, 604 8, 623 2368
Abstract:
A pyloric valve for regulating the flow of fluids in the pyloric region a patient's gastrointestinal tract is disclosed herein. In one embodiment, a pyloric valve includes a plurality of axially connected blocking members located along a longitudinal axis of the valve in a proximal to distal direction. Each blocking member of the valve preferably includes at least one blocking portion defining at least one entryway adapted to receive fluids such as chyme therethrough. The at least one entryway of each blocking member is preferably not aligned with the at least one entryway of each blocking member adjacent thereto along the longitudinal axis. The non-alignment of the at least one entryways of the blocking members preferably creates a non-linear path for fluids such as chyme to travel through the pyloric region of the patient.

Pyloric Valve

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US Patent:
8517972, Aug 27, 2013
Filed:
Jun 22, 2012
Appl. No.:
13/530253
Inventors:
Marc Graham - Somerville MA, US
Buket Grau - Arlington MA, US
Assignee:
E2 LLC - Morris Plains NJ
International Classification:
A61F 2/04
US Classification:
604 8, 623 2368
Abstract:
A pyloric valve for regulating the flow of fluids in the pyloric region a patient's gastrointestinal tract is disclosed herein. In one embodiment, a pyloric valve includes a plurality of axially connected blocking members located along a longitudinal axis of the valve in a proximal to distal direction. Each blocking member of the valve preferably includes at least one blocking portion defining at least one entryway adapted to receive fluids such as chyme therethrough. The at least one entryway of each blocking member is preferably not aligned with the at least one entryway of each blocking member adjacent thereto along the longitudinal axis. The non-alignment of the at least one entryways of the blocking members preferably creates a non-linear path for fluids such as chyme to travel through the pyloric region of the patient.

Pyloric Valve Devices And Methods

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US Patent:
8579849, Nov 12, 2013
Filed:
Feb 1, 2012
Appl. No.:
13/363509
Inventors:
Buket Grau - Arlington MA, US
David Robert Gale - Cambridge, GB
Sam Anne Musgrave - Cambridge, GB
George McGee Perkins - Cambridge, GB
Mark Jeffrey Edhouse - Levin, NZ
Marc Graham - Somerville MA, US
Christopher Kadamus - Jamaica Plain MA, US
Assignee:
E2 LLC - Morris Plains NJ
International Classification:
A61M 5/00
A61F 2/04
US Classification:
604 9, 604 8, 623 2365, 623 2368
Abstract:
A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having a disc-shaped inlet and a helical flange. The helical flange may be disposed in a contracted position defining a contracted length and a contracted diameter and an extended position defining an extended length and an extended diameter, wherein the extended length is longer than the contracted length and the extended diameter is smaller than the contracted diameter. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its contracted and extended positions. Insertion and removal systems are also provided for use with the pyloric valve.

Pyloric Valve Devices And Methods

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US Patent:
20090259239, Oct 15, 2009
Filed:
Apr 9, 2009
Appl. No.:
12/384898
Inventors:
Buket Grau - Arlington MA, US
David Robert Gale - Cambridge, GB
Sam Anne Musgrave - Cambridge, GB
George McGee Perkins - Cambridge, GB
Mark Jeffrey Edhouse - Levin, NZ
Marc Graham - Somerville MA, US
Christopher Kadamus - Jamaica Plain MA, US
Assignee:
Stryker Development LLC - Cambridge MA
International Classification:
A61B 17/08
US Classification:
606153
Abstract:
A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having at least one axially-aligned annular flange defining a central opening and a support having a rim and a support surface. The support may be disposed in a nested position wherein the support surface is disposed within the central opening and an inverted position wherein the support surface is disposed away from the central opening. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its inverted and nested positions. Insertion and removal systems are also provided for use with the pyloric valve.

Pyloric Valve Devices And Methods

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US Patent:
20130006381, Jan 3, 2013
Filed:
Dec 23, 2011
Appl. No.:
13/336196
Inventors:
Buket Grau - Arlington MA, US
David Robert Gale - Cambridge, GB
Sam Anne Musgrave - Cambridge, GB
George McGee Perkins - Cambridge, GB
Mark Jeffrey Edhouse - Levin, NZ
Marc Graham - Somerville MA, US
Christopher Kadamus - Jamaica Plain MA, US
Assignee:
E2 LLC - Morris Plains NJ
International Classification:
A61F 2/04
US Classification:
623 2368
Abstract:
A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having at least one axially-aligned annular flange defining a central opening and a support having a rim and a support surface. The support may be disposed in a nested position wherein the support surface is disposed within the central opening and an inverted position wherein the support surface is disposed away from the central opening. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its inverted and nested positions. Insertion and removal systems are also provided for use with the pyloric valve.
Buket E Grau from Arlington, MA, age ~51 Get Report