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Bruce Klitzman Phones & Addresses

  • 3015 Wade Rd, Durham, NC 27705 (919) 489-0680
  • Littleton, NC
  • Seattle, WA
  • New York, NY

Resumes

Resumes

Bruce Klitzman Photo 1

Assoc Professor

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Location:
Durham, NC
Industry:
Higher Education
Work:
Duke University and Profusa
Associate Professor at Duke Univ and Research Physiologist at Profusa

Duke University
Assoc Professor
Education:
University of Virginia 1974 - 1979
Doctorates, Doctor of Philosophy, Physiology
Duke University 1970 - 1974
Bachelor of Science In Engineering, Bachelors, Biomedical Engineering
Skills:
Science
Biomedical Engineering
Microscopy
Research
Teaching
Life Sciences
Public Speaking
Biomaterials
Neuroscience
Cell Culture
Biotechnology
Physiology
Clinical Research
Lifesciences
Policy Analysis
Grants
Entrepreneurship
Diabetes
Curriculum Development
Biodesign
Medical Monitoring
Medical Device Development
Medical Device Commercialization
Bruce Klitzman Photo 2

Assoc Prof At Duke Univ

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Position:
Assoc Prof at Duke Univ
Location:
Raleigh-Durham, North Carolina Area
Industry:
Higher Education
Work:
Duke Univ
Assoc Prof

Business Records

Name / Title
Company / Classification
Phones & Addresses
Bruce Klitzman
Principal
Option Technologies
Mfg Chemical Preparations
3015 Wade Rd, Durham, NC 27705
Bruce Klitzman
Director Of Surgery
Humacyte, Inc
Commercial Physical Research · Mfg Aircraft · Research and Development On Aircraft
PO Box 12695, Durham, NC 27709
7020 Kit Crk Rd, Durham, NC 27709
7020 Kit Crk Rd, Cary, NC 27560
(919) 597-6595

Publications

Us Patents

Modified Tissue Marking Pigment And Method For Modifying Tissue Marking Pigment

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US Patent:
20080028990, Feb 7, 2008
Filed:
Jul 14, 2005
Appl. No.:
11/571962
Inventors:
Bruce Klitzman - Durham NC, US
Assignee:
FREEDOM-2, LLC - New York NY
International Classification:
C09D 11/00
US Classification:
106493000, 106401000
Abstract:
The invention provides a modified tissue marking pigment and a method for preparing a modified tissue marking pigment by altering protein adsorption to the surface of the pigment particle, activation of key receptors on important immune cells or altering the pigment particle morphology.

Cellular Or Organelle-Entrapped Nanoparticles

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US Patent:
20090217840, Sep 3, 2009
Filed:
Aug 2, 2006
Appl. No.:
12/064223
Inventors:
Ljiljana Kundakovic - Brookline MA, US
Bruce Klitzman - Durham NC, US
Kim Edward Koger - Tequesta FL, US
Edith Mathiowitz - Brookline MA, US
Craig A. Drill - New York NJ, US
Assignee:
FREEDOM-2, INC. - Cherry Hill NJ
International Classification:
C09D 11/00
US Classification:
106 3103
Abstract:
The invention provides tissue marking pigment or dye particle retained within a tissue cell, the cellular cytoplasm, or one or more intracellular organelles. Also, the invention provides nanoparticles, which are phagocytosed, engulfed or otherwise entrapped by cells.

Tattoo Inks

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US Patent:
60131225, Jan 11, 2000
Filed:
Aug 18, 1998
Appl. No.:
9/135814
Inventors:
Bruce Klitzman - Durham NC
Kim Edward Koger - Tequesta FL
Assignee:
Option Technologies, Inc. - Durham NC
International Classification:
C09D 1100
US Classification:
106 3103
Abstract:
Tattoo inks are composed of pigments or dyes combined with a tattoo pigment vehicle which entraps, encases, incorporates, complexes, encapsulates, or is otherwise associated with the pigment to form pigment/vehicle complexes that retain the pigment in the tissue. The vehicle can be chosen so that pigments which alone are unsuitable for tattooing can be used for tattooing and optionally can be retained in the tissue permanently. Alternatively, the vehicle renders the tattoo erasable, wherein the tattoo disappears after imposition of an exogenous energy. Alternatively, the tattoo pigment vehicle renders the tattoo semi-permanent, so that the tattoo spontaneously disappears at a predetermined time.

Intravascular Membrane Oxygenator Catheter With Oscillating Hollow Fiber Membranes

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US Patent:
20230110567, Apr 13, 2023
Filed:
Oct 10, 2022
Appl. No.:
17/962966
Inventors:
- Durham NC, US
Stewart Farling - Durham NC, US
Bruce Klitzman - Durham NC, US
Marc Deshusses - Durham NC, US
Travis Vesel - Durham NC, US
Ira Cheifetz - Durham NC, US
International Classification:
A61M 60/122
Abstract:
The present disclosure describes intravascular oxygenation systems and methods with one or more of improved oxygen diffusion flux, improved resistance to bubble formation on the surface of non-porous hollow fibers, and reduced size. The systems and methods include a pneumatic inlet coupled to a pneumatic source that provides a gas containing oxygen at a high pressure. A plurality of hollow fiber membranes (HFM) are in pneumatic communication with the pneumatic inlet to receive the gas containing oxygen and with an outlet to exhaust a partially deoxygenated gas. An electronic controller drives the motor to oscillate the plurality of HFMs to cause a diffusive flux of the gas containing oxygen from the plurality of HFMs into a region of interest of a subject. The electronic controller may drive the motor according to an oscillation pattern, which may include a macro-oscillation with superimposed micro-oscillations.

Compositions For Real-Time Oxygen Measurements And Methods Of Making And Using Same

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US Patent:
20200061214, Feb 27, 2020
Filed:
Feb 23, 2018
Appl. No.:
16/488434
Inventors:
- Durham NC, US
John Wu - Durham NC, US
Ryan Schweller - Durham NC, US
Bruce Klitzman - Durham NC, US
International Classification:
A61K 49/00
A61B 5/00
A61B 5/1455
Abstract:
The present disclosure provides compositions and methods for real-time oxygen measurements. More particularly, the present disclosure relates to oxygen-sensing compositions including a metalloporphyrin compound.

Device And Method For Reducing Intraocular Pressure

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US Patent:
20190358086, Nov 28, 2019
Filed:
Aug 5, 2019
Appl. No.:
16/532436
Inventors:
- Research Triangle Park NC, US
Rand Allingham - Durham NC, US
Bruce Klitzman - Durham NC, US
Sanjay Asrani - Chapel Hill NC, US
International Classification:
A61F 9/007
Abstract:
An apparatus is provided for draining aqueous humor from an eye for reducing intraocular pressure. The draining apparatus comprises a tube defining a passage for fluid flow between an inlet end and an outlet end. An outlet assembly contacts the conjunctival layer externally of the eyeball. The outlet assembly comprises a housing in fluid communication with the outlet end of the tube and having an aperture for allowing egress of aqueous humor onto the external ocular surface. A resistive component is disposed in the housing for providing resistance to a flow of aqueous humor. A pair of tabs project outwardly and are adapted to be disposed subconjunctivally for securing the draining apparatus relative to the eyeball.

Intravascular Membrane Oxygenator Catheter Systems And Methods

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US Patent:
20190314567, Oct 17, 2019
Filed:
Apr 11, 2018
Appl. No.:
15/950517
Inventors:
- Durham NC, US
Ken Gall - Durham NC, US
Bruce Klitzman - Durham NC, US
Ira Cheifetz - Durham NC, US
Roy Glenn Morris - Conway AR, US
Travis Vesel - Durham NC, US
Jennifer Chien - Durham NC, US
International Classification:
A61M 1/16
Abstract:
Intravascular membrane oxygenator catheter systems and methods are disclosed, along with methods of making and using the same. A catheter system includes a catheter shaft having a wall that extends from a proximal end to a distal end along a longitudinal axis to define a lumen, a plurality of hollow fiber membrane loops each having a proximal portion positioned within the lumen of the catheter shaft and a distal portion extending beyond the lumen of the catheter shaft, the hollow fiber membrane loops are nonporous with solid walls; a pneumatic source in pneumatic communication with the hollow fiber membrane loops. The pneumatic source provides a gas containing oxygen at a pressure sufficient to cause a diffusive flux of the gas containing oxygen from an interior of the hollow fiber membrane loops to a fluid exterior to the hollow fiber membrane loops in a region of interest of a subject.

Device And Method For Reducing Intraocular Pressure

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US Patent:
20180325733, Nov 15, 2018
Filed:
Jul 23, 2018
Appl. No.:
16/043099
Inventors:
- Research Triangle Park NC, US
Rand Allingham - Durham NC, US
Bruce Klitzman - Durham NC, US
Sanjay Asrani - Chapel Hill NC, US
International Classification:
A61F 9/007
Abstract:
An apparatus is provided for draining aqueous humor from an eye for reducing intraocular pressure. The draining apparatus comprises a tube defining a passage for fluid flow between an inlet end and an outlet end. An outlet assembly contacts the conjunctival layer externally of the eyeball. The outlet assembly comprises a housing in fluid communication with the outlet end of the tube and having an aperture for allowing egress of aqueous humor onto the external ocular surface. A resistive component is disposed in the housing for providing resistance to a flow of aqueous humor. A pair of tabs project outwardly and are adapted to be disposed subconjunctivally for securing the draining apparatus relative to the eyeball.
Bruce Maurice Klitzman from Durham, NC, age ~73 Get Report