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Brian Edwin Cathers

from San Mateo, CA
Age ~54
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Also known as:
Brian E Cathers, Brain Edwin Cathers, Brian E Cahter, Bryan Cathers, Cathers Bryan, Brian S
Related to:
Tyler HollowaySusan E Cathers, 54B Cathers, 54Todd S Larson, 55Christine M Battistoni, 54Robert E LarsonTraci L Lemke, 56Traci L Honosky, 56Harry D Holloway, 60Trevor Honosky, 58Susan L Larson, 77Deborah L Honosky, 62
Connected to:
Christopher N Cathers, 51Craig M Cathers, 41Curtis S Cathers, 52Cynthia D Cathers, 70David Catherson, 59James T Cathers, 79John D Cathers, 73Maryjane J Cathers, 81Michele C Cathers, 71Crystal L Catherwood, 42

Brian Cathers Phones & Addresses

  • San Mateo, CA
  • La Jolla, CA
  • 10040 Branford Rd, San Diego, CA 92129 (858) 484-8903 (858) 943-9175
  • 13041 Avenida Del General, San Diego, CA 92129 (858) 484-8903
  • 1216 Redman Ave, Mesquite, TX 75149
  • 1220 Redman Ave, Mesquite, TX 75149
  • 2414 Ravenwood Ct, Mansfield, TX 76063
  • Burleson, TX
  • Dallas, TX
  • Austin, TX
  • 13041 Avenida Del General, San Diego, CA 92129

Work

Position: Executive, Administrative, and Managerial Occupations

Education

Degree: Associate degree or higher

Publications

Us Patents

Methods Of Modulating Inflammatory Cell Recruitment And Gene Expression Using Haloaryl Substituted Aminopurines

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US Patent:
8440661, May 14, 2013
Filed:
May 13, 2010
Appl. No.:
12/779083
Inventors:
Brydon L. Bennett - San Diego CA, US
Kate Northcote - San Diego CA, US
Brian Edwin Cathers - San Diego CA, US
Assignee:
Signal Pharmaceuticals, LLC - San Diego CA
International Classification:
A61P 11/00
C07D 473/32
C07D 239/50
C07D 239/48
A61K 31/53
A61P 3/10
US Classification:
5142342, 5142634
Abstract:
Provided herein are Aminopurine Compounds having the following structure:.

Viral Enzyme Activated Prototoxophores And Use Of Same To Treat Viral Infections

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US Patent:
20030114385, Jun 19, 2003
Filed:
Apr 26, 2002
Appl. No.:
10/133133
Inventors:
Brian Cathers - San Diego CA, US
Saskia Neuteboon - San Diego CA, US
H. Shepard - Encinitas CA, US
International Classification:
A61K038/08
C07K007/06
C07K007/08
US Classification:
514/016000, 530/329000, 530/328000
Abstract:
A synthetic prototoxophore, which is a relatively non-toxic compound that includes a toxin moiety and a substrate domain for a viral enzyme, is provided. Upon binding of a viral enzyme to the substrate domain, the catalytic activity of the viral enzyme converts the prototoxophore to a toxophore, which is toxic to a cell. Thus, a toxophore also is provided, as is a pharmaceutical composition containing a prototoxophore, and kits containing a prototoxophore. Also provided are methods of using a prototoxophore to reduce or inhibit viral infectivity, and methods of using a prototoxophore to ameliorate the severity of a viral infection in an individual.

Methods For Identifying Therapeutic Targets For Treating Infectious Disease

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US Patent:
20030130179, Jul 10, 2003
Filed:
Jul 20, 2001
Appl. No.:
09/910345
Inventors:
H. Shepard - Encinitas CA, US
David Lackey - San Diego CA, US
Brian Cathers - San Diego CA, US
Maria Sergeeva - San Diego CA, US
International Classification:
A61K038/17
C12Q001/70
G01N033/53
US Classification:
514/012000, 435/005000, 435/007100
Abstract:
This invention provides methods and systems to identify enzymes that act as enzyme catalyzed therapeutic activators and the enzymes identified by these methods. Also provided by this invention are compounds activated by the enzymes as well as compositions containing these compounds.

Methods Of Treatment, Improvement And Prevention Using Haloaryl Substituted Aminopurines

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US Patent:
20120129807, May 24, 2012
Filed:
Oct 20, 2011
Appl. No.:
13/277282
Inventors:
Brydon L. Bennett - San Diego CA, US
Brian Edwin Cathers - San Diego CA, US
Heather Raymon - San Diego CA, US
Weilin Xie - San Diego CA, US
Jaman May Maroni - Watchung NJ, US
International Classification:
A61K 31/69
A61K 31/5377
A61P 17/00
A61K 31/551
A61P 17/06
A61P 17/04
A61P 1/04
A61P 1/00
A61P 1/10
A61P 19/02
A61P 17/14
A61P 11/00
A61P 17/02
A61P 1/12
A61K 31/52
US Classification:
514 64, 5142634, 51426322, 51426323, 51426324, 5142632, 5142342, 51425216, 514218, 51425211
Abstract:
Provided herein are Aminopurine Compounds having the following structure:wherein R, Rand Rare as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing scleroderma, keloids, UV injury, or sunburn, and methods for improving or preventing scar formation.

Methods Of Treatment And Prevention Using Haloaryl Substituted Aminopurines

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US Patent:
7759342, Jul 20, 2010
Filed:
Feb 15, 2007
Appl. No.:
11/708150
Inventors:
Brydon L. Bennett - San Diego CA, US
Kate Blease - San Diego CA, US
Brian Edwin Cathers - San Diego CA, US
Assignee:
Signal Pharmaceuticals, LLC - San Diego CA
International Classification:
A61P 11/00
C07D 473/32
C07D 239/50
C07D 239/48
A61K 31/53
A61P 3/10
US Classification:
5142342, 5142634
Abstract:
Provided herein are Aminopurine Compounds having the following structure:.

Antiproliferative Compounds And Methods Of Use Thereof

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US Patent:
20220280505, Sep 8, 2022
Filed:
Nov 8, 2021
Appl. No.:
17/521432
Inventors:
- Summit NJ, US
Gordon L. Bray - San Francisco CA, US
James Carmichael - Nottingham, GB
Soraya Carrancio - San Diego CA, US
Brian E. Cathers - San Diego CA, US
Matthew D. Correa - San Diego CA, US
Joshua Hansen - La Jolla CA, US
Courtney G. Havens - San Diego CA, US
Timothy S. Kercher - Longmont CO, US
Xiaoling Lu - Whippany NJ, US
Hon-Wah Man - Princeton NJ, US
Mark A. Nagy - Encinitas CA, US
Rama K. Narla - San Diego CA, US
Joseph R. Piccotti - Encinitas CA, US
Daniel W. Pierce - Belmont CA, US
Brandon W. Whitefield - San Diego CA, US
Lilly L. Wong - Solana Beach CA, US
Nanfei Zou - Fanwood NJ, US
International Classification:
A61K 31/496
A61P 35/02
A61K 31/573
A61K 38/05
C07D 401/04
A61P 35/00
Abstract:
Provided herein is 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, and methods for treating, preventing or managing multiple myeloma using such compounds. Also provided are pharmaceutical compositions comprising the compounds, and methods of use of the compositions.

Compositions And Methods For Inducing Conformational Changes In Cereblon And Other E3 Ubiquitin Ligases

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US Patent:
20210000813, Jan 7, 2021
Filed:
Apr 17, 2020
Appl. No.:
16/852360
Inventors:
- Summit NJ, US
Brian E. Cathers - San Diego CA, US
Assignee:
Celgene Corporation - Summit NJ
International Classification:
A61K 31/454
A61K 31/517
C12Q 1/37
Abstract:
Provided herein are compositions, therapeutic methods, screening methods, computational methods and biomarkers based upon the elucidation of the interaction among cereblon, its substrates and certain compounds or agents, including small molecules, peptides, and proteins.

Antiproliferative Compounds And Methods Of Use Thereof

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US Patent:
20200253964, Aug 13, 2020
Filed:
Apr 27, 2020
Appl. No.:
16/859357
Inventors:
- Summit NJ, US
Gordon L. Bray - San Francisco CA, US
James Carmichael - Nottingham, GB
Soraya Carrancio - San Diego CA, US
Brian E. Cathers - San Diego CA, US
Matthew D. Correa - San Diego CA, US
Joshua Hansen - La Jolla CA, US
Courtney G. Havens - San Diego CA, US
Timothy S. Kercher - Longmont CO, US
Xiaoling Lu - Whippany NJ, US
Hon-Wah Man - Princeton NJ, US
Mark A. Nagy - Encinitas CA, US
Rama K. Narla - San Diego CA, US
Joseph R. Piccotti - Encinitas CA, US
Daniel W. Pierce - Belmont CA, US
Brandon W. Whitefield - San Diego CA, US
Lilly L. Wong - Solana Beach CA, US
Nanfei Zou - Fanwood NJ, US
International Classification:
A61K 31/496
A61P 35/00
C07D 401/04
A61K 38/05
A61K 31/573
A61P 35/02
Abstract:
Provided herein is 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, and methods for treating, preventing or managing multiple myeloma using such compounds. Also provided are pharmaceutical compositions comprising the compounds, and methods of use of the compositions.
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Brian Edwin Cathers from San Mateo, CA, age ~54 Get Report