US Patent:
20170335415, Nov 23, 2017
Inventors:
- LIVERMORE CA, US
Nicholas A. BE - OAKLAND CA, US
Brian BENNION - TRACY CA, US
Tim CARPENTER - LIVERMORE CA, US
Heather Ann ENRIGHT - LIVERMORE CA, US
Felice LIGHTSTONE - FREMONT CA, US
Mike MALFATTI - SAN RAMON CA, US
Margaret Windy MCNERNEY - PLEASANTON CA, US
Tuan H. NGUYEN - LIVERMORE CA, US
International Classification:
C07C 251/58
A61K 31/4192
A61K 31/15
C07D 241/04
A61K 31/221
C07D 213/20
Abstract:
Described herein are oxime compounds capable of inactivating a nerve agent, blood brain barrier (BBB)-penetration, and/or reactivation of nerve agent-inhibited acetylcholinesterase (AChE) and related methods, systems and compositions for inactivation of one or more nerve agents, therapeutic and/or prophylactic treatment of an individual, and/or decomposition of nerve agent for decontamination.